Table of Contents
Foreword ............................................................................................. V
Preface ............................................................................................. VII
Table of Abbreviations .................................................................... XI
1 Introduction ................................................................................... 1
1.1
Umpolung ....................................................................................... 1
1.2
Amide Activation ............................................................................ 5
1.3
Smiles Rearrangement .................................................................... 9
2 Results and Discussion ................................................................ 11
2.1
Nucleophilic α-Functionalisation of Amides ................................ 11
2.1.1 Amination ......................................................................... 11
2.1.2 Oxygenation...................................................................... 17
2.2
Arylation via a Smiles rearrangement ........................................... 19
3 Conclusion and Perspectives ...................................................... 25
3.1
Conclusion .................................................................................... 25
3.2
Enantioselective -Amination ...................................................... 25
3.3
-Amination .................................................................................. 26
4 Experimental Data ...................................................................... 27
References ......................................................................................... 57