4 Experimental Data
31
1.2h Methyl tosylglycinate
The product was prepared from 381 mg (2 mmol) 4-methylbenzenesulfonyl chloride, 281 mg (2 mmol) glycine methyl ester hydrochloride and 506 mg (5 mmol)
trimethylamine in 91% (445 mg) yield according to the general procedure B. All
spectroscopic properties are in good accordance with reported data.
[47]
1.2i N-Methyl-2-nitrobenzenesulfonamide
The product was prepared from 665 mg (3 mmol) 2-nitrobenzenesulfonyl chloride
and 4.5 mL (9 mmol) methylamine (in THF 2 M) in 93% (600 mg) yield according
to the general procedure B. All spectroscopic properties are in good accordance
with reported data.
[48]
1.2j N-Methylnaphthalene-2-sulfonamide
The product was prepared from 453 mg (2 mmol) naphthalene-2-sulfonyl chloride
and 3 mL (6 mmol) methylamine (in THF 2 M) in 96% (423 mg) yield according
to the general procedure B. All spectroscopic properties are in good accordance
with reported data.
[49]
The synthesis of pyridine derived sulfonamides 1.2l,m is a modified version
of Wright et al.’s method.
[50]