138
4 Applications of Nitrile Imine Derivatives
Si
OH
N
N
NPh
N
O
HN
PhMe
80 o C, 2 h
OH
OH
Si(OEt)3
Si
O
OH
O
Si(OEt)2
(EtO)2Si
HN
NH
O
O
N
N
NPh
N
N
N
NPh
N
rt, 10 min
Si
O
O H O
(EtO)2Si
Si(OEt)2
NH
H
N
O
O
PhN
N
N
PhN
N N
OH
OH
HO
OH
OH
OH
h
Mirror
Scheme 4.45 The application of NI chemistry and microcontact printing in the patterning of
surfaces
=
N 3
N
O
O
O
O
O
N
O
O
O
O
O
N
N
N
N
O
O
O
O
N
N
N
Si
O
OH
O
Si(OEt) 2
(EtO) 2 Si
HN
NH
O
O
N
N
NPh
N
N
N
NPh
N
CuBr, PMDETA,
THF,
50
o C, 1 h
DMF
130
o
C, 1 h
Si
O
OH
O
Si(OEt) 2
(EtO) 2 Si
HN
NH
O
O
N
NPh
N
NPh
N
N
O
O
O
O
o-DCB
rt, 10 min
h
N
O
n
Scheme 4.46 Direct polymer ligation using NI-maleimide cycloaddition