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75. Van Den Brink FWB, Van Der Velde G (1986) Observations on the seasonal and yearly
occurrence and the distribution of Atyaephyra desmarestii (Millet, 1831) (Crustacea,
Decapoda, Natantia) in the Netherlands. Hydrobiol Bull 19:193–198
76. CEC (1996) (Commission of The European Communities) Technical Guidance Document in
Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances and Commission Regulation (EC) No 1488/94 on Risk Assessment for Existing
Substances. Part II: Environmental Risk Assessment, Office for Official Publications of
European Communities, Luxembourg
77. Sathishkumar P, Meena RAA, Palanisami T, Ashokkumar V, Palvannan T, Gu FL (2020)
Occurrence, interactive effects and ecological risk of diclofenac in environmental compartments and biota - a review. Sci Total Environ 698:134057
78. Biel-Maeso M, Baena-Nogueras RM, Corada-Fernandez C, Lara-Martin PA (2018) Occurrence, distribution and environmental risk of pharmaceutically active compounds (PhACs) in
coastal and ocean waters from the Gulf of Cadiz (SW Spain). Sci Total Environ 612:649–659
79. Guruge KS, Goswami P, Tanoue R, Nomiyama K, Wijesekara RGS, Dharmaratne TS (2019)
First nationwide investigation and environmental risk assessment of 72 pharmaceuticals and
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80. Ma R, Wang B, Lu S et al (2016) Characterization of pharmaceutically active compounds in
Dongting Lake, China: occurrence, chiral profiling and environmental risk. Sci Total Environ
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81. Mutiyar PK, Gupta SK, Mittal AK (2018) Fate of pharmaceutical active compounds (PhACs)
from River Yamuna, India: an ecotoxicological risk assessment approach. Ecotoxicol Environ
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82. Quinn B, Gagné F, Blaise C (2008) An investigation into the acute and wastewater effluent on
the cnidarians, Hydra attenuate. Sci Total Environ 14:306–389
83. Braunbeck T, Kais B, Lammer E, Otte J, Pelka K, Stengel D, Strecker R (2014) The fish
embryo test (FET): origin, applications, and future. Environ Sci Pollut Res 22:16247–16261
84. Ramesh M, Anitha S, Poopala RK, Shobana C (2018) Evaluation of acute and sublethal effects
of chloroquine (C18H26CIN3) on certain enzymological and histopathological biomarker
responses of a freshwater fish Cyprinus carpio. Toxicol Rep 5:18–27
85. Nieto E, Hampel M, González-Ortegón E, Drake P, Blasco J (2016) Influence of temperature
on toxicity of single pharmaceuticals and mixtures, in the crustacean A. desmarestii. J Hazard
Mater 313(5):159–169
86. Eades C, Waring CP (2010) The effects of diclofenac on the physiology of the greenshore crab
Carcinus maenas. Mar Environ Res 69(1):S46–S48
87. González-Ortegón E, Blasco J, Nieto E, Hampel M, Giménez L (2016) Individual and mixture
effects of selected pharmaceuticals on larval development of the estuarine shrimp Palaemon
longirostris. Sci Total Environ 540(1):260–266
88. Radović TT, Grujić SD, Kovačević SR, Laušević MD, Dimkić MA (2016) Sorption of
selected pharmaceuticals and pesticides on different river sediments. Environ Sci Pollut Res
23:25232–25244
89. Hampel M, Moreno-Garrido I, González-Mazo E, Blasco J (2009) Suitability of the marine
prosobranch snail Hydrobia ulvae for sediment toxicity assessment: A case study with the
anionic surfactant linear alkylbenzene sulphonate (LAS). Ecotoxicol Environ Saf
72:1303–1308
90. Gilroy ÈAM, Balakrishnan VK, Solomon KR, Sverko E, Sibley PK (2012) Behaviour of
pharmaceuticals in spiked lake sediments – effects and interactions with benthic invertebrates.
Chemosphere 86:578–584
91. Heye K, Becker D, Lütke Eversloh C, Durmaz V, Ternes TA, Oetken M, Oehlmann J (2016)
Effects of carbamazepine and two of its metabolites on the non-biting midge Chironomus
riparius in a sediment full life cycle toxicity test. Water Res 98:19–27
188
C. Trombini et al.
Mémoires de la Sociétéd'Agriculture, Sciences et Arts d'Angers 1:55–57
75. Van Den Brink FWB, Van Der Velde G (1986) Observations on the seasonal and yearly
occurrence and the distribution of Atyaephyra desmarestii (Millet, 1831) (Crustacea,
Decapoda, Natantia) in the Netherlands. Hydrobiol Bull 19:193–198
76. CEC (1996) (Commission of The European Communities) Technical Guidance Document in
Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances and Commission Regulation (EC) No 1488/94 on Risk Assessment for Existing
Substances. Part II: Environmental Risk Assessment, Office for Official Publications of
European Communities, Luxembourg
77. Sathishkumar P, Meena RAA, Palanisami T, Ashokkumar V, Palvannan T, Gu FL (2020)
Occurrence, interactive effects and ecological risk of diclofenac in environmental compartments and biota - a review. Sci Total Environ 698:134057
78. Biel-Maeso M, Baena-Nogueras RM, Corada-Fernandez C, Lara-Martin PA (2018) Occurrence, distribution and environmental risk of pharmaceutically active compounds (PhACs) in
coastal and ocean waters from the Gulf of Cadiz (SW Spain). Sci Total Environ 612:649–659
79. Guruge KS, Goswami P, Tanoue R, Nomiyama K, Wijesekara RGS, Dharmaratne TS (2019)
First nationwide investigation and environmental risk assessment of 72 pharmaceuticals and
personal care products from Sri Lankan surface waterways. Sci Total Environ 690:683–695
80. Ma R, Wang B, Lu S et al (2016) Characterization of pharmaceutically active compounds in
Dongting Lake, China: occurrence, chiral profiling and environmental risk. Sci Total Environ
557–558:268–275
81. Mutiyar PK, Gupta SK, Mittal AK (2018) Fate of pharmaceutical active compounds (PhACs)
from River Yamuna, India: an ecotoxicological risk assessment approach. Ecotoxicol Environ
Saf 150:297–304
82. Quinn B, Gagné F, Blaise C (2008) An investigation into the acute and wastewater effluent on
the cnidarians, Hydra attenuate. Sci Total Environ 14:306–389
83. Braunbeck T, Kais B, Lammer E, Otte J, Pelka K, Stengel D, Strecker R (2014) The fish
embryo test (FET): origin, applications, and future. Environ Sci Pollut Res 22:16247–16261
84. Ramesh M, Anitha S, Poopala RK, Shobana C (2018) Evaluation of acute and sublethal effects
of chloroquine (C18H26CIN3) on certain enzymological and histopathological biomarker
responses of a freshwater fish Cyprinus carpio. Toxicol Rep 5:18–27
85. Nieto E, Hampel M, González-Ortegón E, Drake P, Blasco J (2016) Influence of temperature
on toxicity of single pharmaceuticals and mixtures, in the crustacean A. desmarestii. J Hazard
Mater 313(5):159–169
86. Eades C, Waring CP (2010) The effects of diclofenac on the physiology of the greenshore crab
Carcinus maenas. Mar Environ Res 69(1):S46–S48
87. González-Ortegón E, Blasco J, Nieto E, Hampel M, Giménez L (2016) Individual and mixture
effects of selected pharmaceuticals on larval development of the estuarine shrimp Palaemon
longirostris. Sci Total Environ 540(1):260–266
88. Radović TT, Grujić SD, Kovačević SR, Laušević MD, Dimkić MA (2016) Sorption of
selected pharmaceuticals and pesticides on different river sediments. Environ Sci Pollut Res
23:25232–25244
89. Hampel M, Moreno-Garrido I, González-Mazo E, Blasco J (2009) Suitability of the marine
prosobranch snail Hydrobia ulvae for sediment toxicity assessment: A case study with the
anionic surfactant linear alkylbenzene sulphonate (LAS). Ecotoxicol Environ Saf
72:1303–1308
90. Gilroy ÈAM, Balakrishnan VK, Solomon KR, Sverko E, Sibley PK (2012) Behaviour of
pharmaceuticals in spiked lake sediments – effects and interactions with benthic invertebrates.
Chemosphere 86:578–584
91. Heye K, Becker D, Lütke Eversloh C, Durmaz V, Ternes TA, Oetken M, Oehlmann J (2016)
Effects of carbamazepine and two of its metabolites on the non-biting midge Chironomus
riparius in a sediment full life cycle toxicity test. Water Res 98:19–27
188
C. Trombini et al.