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environment: from emerging problem to. Ann Pharmacol Pharm 2(14):1–3
2. Wongrakpanich S et al (2018) A comprehensive review of non-steroidal anti-inflammatory drug
use in the elderly. Aging Dis 9(1):143. https://doi.org/10.14336/AD.2017.0306
3. Pirlamarla P, Bond RM (2016) FDA labeling of NSAIDs: review of nonsteroidal antiinflammatory drugs in cardiovascular disease. Trends Cardiovasc Med 26(8):675–680.
https://doi.org/10.1016/j.tcm.2016.04.011
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jhazmat.2009.10.100
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7. Chatterjee N, Walker GC (2017) Agriculture’s food safety and inspection service. Environ Mol
Mutagen 368:363–368
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(8–9):1109–1115. https://doi.org/10.1016/j.dnarep.2004.03.002
9. Sinha S et al (2007) Uptake and translocation of metals in Spinacia oleracea L. grown on
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chemosphere.2006.08.026
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org/10.1042/BJ20151227
11. Zhang W, Xiao S, Ahn DU (2013) Protein oxidation: basic principles and implications for meat
quality. Crit Rev Food Sci Nutr 53(11):1191–1201. https://doi.org/10.1080/10408398.2011.
577540
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Proteins Proteomics 1703(2):93–109. https://doi.org/10.1016/j.bbapap.2004.08.007
13. Shacter E (2000) Quantification and significance of protein oxidation in biological samples.
Drug Metab Rev 32(3–4):307–326. https://doi.org/10.1081/DMR-100102336
14. Burton GJ, Jauniaux E (2011) Oxidative stress. Best Pract Res Clin Obstet Gynaecol 25
(3):287–299. https://doi.org/10.1016/j.bpobgyn.2010.10.016
15. Doi H et al (2002) Chemiluminescence associated with the oxidative metabolism of salicylic
acid in rat liver microsomes. Chem Biol Interact 140(2):109–119. https://doi.org/10.1016/
S0009-2797(02)00004-2
16. Jifa W et al (2006) Response of integrated biomarkers of fish (Lateolabrax japonicus) exposed
to benzo[a]pyrene and sodium dodecylbenzene sulfonate. Ecotoxicol Environ Saf 65
(2):230–236. https://doi.org/10.1016/j.ecoenv.2005.08.002
17. Ayala A, Muñoz MF, Argüelles S (2014) Lipid peroxidation: production, metabolism, and
signaling mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal. Oxid Med Cell Longev
2014:360438. https://doi.org/10.1155/2014/360438
18. Devaki M, Nirupama R, Yajurvedi H (2011) Reduced antioxidant status for prolonged period
due to repeated stress exposure in rat. J Stress Physiol Biochem 7(2):139–147
19. Emad S et al (2017) Attenuation of stress induced memory deficits by nonsteroidal antiinflammatory drugs (NSAIDs) in rats: Role of antioxidant enzymes. Pharmacol Rep 69
(2):300–305. https://doi.org/10.1016/j.pharep.2016.11.009
20. Stadtman ER (1990) Mechanism and biological consequences. Free Radic Biol Med 9
(1987):315–325
21. Matés JM, Pérez-Gómez C, De Castro IN (1999) Antioxidant enzymes and human diseases.
Clin Biochem 32(8):595–603. https://doi.org/10.1016/S0009-9120(99)00075-2
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1. Sharma K, Kaushik G (2017) Annals of pharmacology and pharmaceutics NSAIDS in the
environment: from emerging problem to. Ann Pharmacol Pharm 2(14):1–3
2. Wongrakpanich S et al (2018) A comprehensive review of non-steroidal anti-inflammatory drug
use in the elderly. Aging Dis 9(1):143. https://doi.org/10.14336/AD.2017.0306
3. Pirlamarla P, Bond RM (2016) FDA labeling of NSAIDs: review of nonsteroidal antiinflammatory drugs in cardiovascular disease. Trends Cardiovasc Med 26(8):675–680.
https://doi.org/10.1016/j.tcm.2016.04.011
4. Santos LHMLM et al (2010) Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J Hazard Mater 175(1–3):45–95. https://doi.org/10.1016/j.
jhazmat.2009.10.100
5. Khetan SK, Collins TJ (2007) Human pharmaceuticals in the aquatic environment: a challenge
to green chemistry. Chemi Rev 107(6):2319–2364. https://doi.org/10.1021/cr020441w
6. Sanganyado E et al (2017) Chiral pharmaceuticals: a review on their environmental occurrence
and fate processes. Water Res 124:527–542. https://doi.org/10.1016/j.watres.2017.08.003
7. Chatterjee N, Walker GC (2017) Agriculture’s food safety and inspection service. Environ Mol
Mutagen 368:363–368
8. Barzilai A, Yamamoto K-I (2004) DNA damage responses to oxidative stress. DNA Repair 3
(8–9):1109–1115. https://doi.org/10.1016/j.dnarep.2004.03.002
9. Sinha S et al (2007) Uptake and translocation of metals in Spinacia oleracea L. grown on
tannery sludge-amended and contaminated soils: effect on lipid peroxidation, morphoanatomical changes and antioxidants. Chemosphere 67(1):176–187. https://doi.org/10.1016/j.
chemosphere.2006.08.026
10. Davies MJ (2016) Protein oxidation and peroxidation. Biochem J 473(7):805–825. https://doi.
org/10.1042/BJ20151227
11. Zhang W, Xiao S, Ahn DU (2013) Protein oxidation: basic principles and implications for meat
quality. Crit Rev Food Sci Nutr 53(11):1191–1201. https://doi.org/10.1080/10408398.2011.
577540
12. Davies MJ (2005) The oxidative environment and protein damage. Biochim Biophys Acta
Proteins Proteomics 1703(2):93–109. https://doi.org/10.1016/j.bbapap.2004.08.007
13. Shacter E (2000) Quantification and significance of protein oxidation in biological samples.
Drug Metab Rev 32(3–4):307–326. https://doi.org/10.1081/DMR-100102336
14. Burton GJ, Jauniaux E (2011) Oxidative stress. Best Pract Res Clin Obstet Gynaecol 25
(3):287–299. https://doi.org/10.1016/j.bpobgyn.2010.10.016
15. Doi H et al (2002) Chemiluminescence associated with the oxidative metabolism of salicylic
acid in rat liver microsomes. Chem Biol Interact 140(2):109–119. https://doi.org/10.1016/
S0009-2797(02)00004-2
16. Jifa W et al (2006) Response of integrated biomarkers of fish (Lateolabrax japonicus) exposed
to benzo[a]pyrene and sodium dodecylbenzene sulfonate. Ecotoxicol Environ Saf 65
(2):230–236. https://doi.org/10.1016/j.ecoenv.2005.08.002
17. Ayala A, Muñoz MF, Argüelles S (2014) Lipid peroxidation: production, metabolism, and
signaling mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal. Oxid Med Cell Longev
2014:360438. https://doi.org/10.1155/2014/360438
18. Devaki M, Nirupama R, Yajurvedi H (2011) Reduced antioxidant status for prolonged period
due to repeated stress exposure in rat. J Stress Physiol Biochem 7(2):139–147
19. Emad S et al (2017) Attenuation of stress induced memory deficits by nonsteroidal antiinflammatory drugs (NSAIDs) in rats: Role of antioxidant enzymes. Pharmacol Rep 69
(2):300–305. https://doi.org/10.1016/j.pharep.2016.11.009
20. Stadtman ER (1990) Mechanism and biological consequences. Free Radic Biol Med 9
(1987):315–325
21. Matés JM, Pérez-Gómez C, De Castro IN (1999) Antioxidant enzymes and human diseases.
Clin Biochem 32(8):595–603. https://doi.org/10.1016/S0009-9120(99)00075-2
112
N. SanJuan-Reyes et al.