310
Acknowledgments
This work has been co-financed by the European Union and Greek
national funds through the program “Support for Researchers
with Emphasis on Young Researchers” (call code: EDBM34, ΚΕ
14995) and under the research title “Preparation and study of
innovative forms of administration of pharmaceutical molecules
targeting at improved pharmacological properties.”
References
1. Fotakis C, Christodouleas D, Zoumpoulakis
P, Kritsi E, Benetis NP, Mavromoustakos T,
Reis H, Gili A, Papadopoulos MG, Zervou
M (2011) Comparative biophysical studies of
Sartan class drug molecules losartan and candesartan (CV-11974) with membrane bilayers.
10 12 14 16 18
20 22 24 26 28 30 32 ºC
10 12 14 16 18
20 22 24 26 28 30 32 ºC
Heat
flow,
Endothem
Heat
flow,
Endothem
=
_
V h = 2°C/min
a
b
c
d
e
a
b
c
d
e
Fig. 5 DSC thermograms of fully hydrated DMPC/DPPG (97:3 molar ratio) lipid
bilayers with varying amounts: (a) 0%, (b) 2, (c) 5%, (d) 10%, (e) 20% (molar)
of CPDs, I—G3; II—G4. Adapted from Ref. [26]
Maria Chountoulesi et al.
Acknowledgments
This work has been co-financed by the European Union and Greek
national funds through the program “Support for Researchers
with Emphasis on Young Researchers” (call code: EDBM34, ΚΕ
14995) and under the research title “Preparation and study of
innovative forms of administration of pharmaceutical molecules
targeting at improved pharmacological properties.”
References
1. Fotakis C, Christodouleas D, Zoumpoulakis
P, Kritsi E, Benetis NP, Mavromoustakos T,
Reis H, Gili A, Papadopoulos MG, Zervou
M (2011) Comparative biophysical studies of
Sartan class drug molecules losartan and candesartan (CV-11974) with membrane bilayers.
10 12 14 16 18
20 22 24 26 28 30 32 ºC
10 12 14 16 18
20 22 24 26 28 30 32 ºC
Heat
flow,
Endothem
Heat
flow,
Endothem
=
_
V h = 2°C/min
a
b
c
d
e
a
b
c
d
e
Fig. 5 DSC thermograms of fully hydrated DMPC/DPPG (97:3 molar ratio) lipid
bilayers with varying amounts: (a) 0%, (b) 2, (c) 5%, (d) 10%, (e) 20% (molar)
of CPDs, I—G3; II—G4. Adapted from Ref. [26]
Maria Chountoulesi et al.
