18 Nutraceutical and Pharmaceutical Applications of Carotenoids
467
Nagaki, Y., Mihara, M., Takahashi, J., Kitamura, A., Horita, Y., Sugiura, Y., et al. (2005). The
effect of astaxanthin on retinal capillary blood flow in normal volunteers. Journal of Clinical
Therapeutics Medicine, 21, 537–542.
Nagaki, Y., Mihara, M., Tsukahara, H., & Ono, S. (2006). The supplementation effect of astaxanthin
on accommodation and asthenopia. Journal of Clinical Therapeutics Medicine, 22, 41–54.
Nakamura, M., Sugiura, M., & Aoki, N. (2006). High β-carotene and β-cryptoxanthin are associated
with low pulse wave velocity. Atherosclerosis, 184, 363–369.
Nakazawa, Y., Sashima, T., Hosokawa, M., & Miyashita, K. (2009). Comparative evaluation of
growth inhibitory effect of stereoisomers of fucoxanthin in human cancer cell lines. Journal of
Functional Foods, 1, 88–97.
Narisawa, T., Fukaura, Y., Hasebe, M., Nomura, S., Oshima, S., & Inakuma, T. (2000). Prevention of
N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin
and capsanthin-rich paprika juice. Proceedings of the Society for Experimental Biology and
Medicine, 224, 116–122.
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., et al. (1996).
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease.
The New England Journal of Medicine, 334, 1150–1155.
Ono, M., Honda, M., Yasuda, K., Kanda, H., & Goto, M. (2018). Production of β-carotene
nanosuspensions using supercritical CO 2 and improvement of its efficiency by Z-isomerization
pre-treatment. Journal of Supercritical Fluids, 138, 124–131.
Østerlie, M., Bjerkeng, B., & Liaaen-Jensen, S. (2000). Plasma appearance and distribution of
astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration
of astaxanthin. Journal of Nutritional Biochemistry, 11, 482–490.
Ouchi, A., Aizawa, K., Iwasaki, Y., Inakuma, T., Terao, J., Nagaoka, S. I., et al. (2010). Kinetic study
of the quenching reaction of singlet oxygen by carotenoids and food extracts in solution. Development of a singlet oxygen absorption capacity (SOAC) assay method. Journal of Agriculture
and Food Chemistry, 58, 9967–9978.
Palozza, P., Parrone, N., Simone, R. E., & Catalano, A. (2010). Lycopene in atherosclerosis prevention: An integrated scheme of the potential mechanisms of action from cell culture studies.
Archives of Biochemistry and Biophysics, 504, 26–33.
Palozza, P., Torelli, C., Boninsegna, A., Simone, R., Catalano, A., Mele, M. C., et al. (2009). Growthinhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer
cells. Cancer Letters, 283, 108–117.
Perry, A., Rasmussen, H., & Johnson, E. J. (2009). Xanthophyll (lutein, zeaxanthin) content in
fruits, vegetables and corn and egg products. Journal of Food Composition and Analysis, 22,
9–15.
Rahman, S. O., Panda, B. P., Parvez, S., Kaundal, M., Hussain, S., Akhtar, M., et al. (2019).
Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in
animal model of Alzheimer’s disease. Biomedicine & Pharmacotherapy, 110, 47–58.
Rammuni, M. N., Ariyadasa, T. U., Nimarshana, P. H. V., & Attalage, R. A. (2019). Comparative assessment on the extraction of carotenoids from microalgal sources: Astaxanthin from H.
pluvialis and β-carotene from D. salina. Food Chemistry, 277, 128–134.
Relevy, N. Z., Rühl, R., Harari, A., Grosskopf, I., Barshack, I., Ben-Amotz, A., et al. (2015). 9-cis
β-Carotene inhibits atherosclerosis development in female LDLR-/-Mice. Functional Foods in
Health and Disease, 5, 67–79.
Roberts, R. L., Green, J., & Lewis, B. (2009). Lutein and zeaxanthin in eye and skin health. Clinics
in Dermatology, 27, 195–201.
Sachindra, N. M., Sato, E., Maeda, H., Hosokawa, M., Niwano, Y., Kohno, M., et al. (2007).
Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and
its metabolites. Journal of Agriculture and Food Chemistry, 55, 8516–8522.
Shirakura, Y., Takayanagi, K., Mukai, K., Tanabe, H., & Inoue, M. (2011). β-Cryptoxanthin
suppresses the adipogenesis of 3T3-L1 cells via RAR activation. Journal of Nutritional Science
and Vitaminology, 57, 426–431.
467
Nagaki, Y., Mihara, M., Takahashi, J., Kitamura, A., Horita, Y., Sugiura, Y., et al. (2005). The
effect of astaxanthin on retinal capillary blood flow in normal volunteers. Journal of Clinical
Therapeutics Medicine, 21, 537–542.
Nagaki, Y., Mihara, M., Tsukahara, H., & Ono, S. (2006). The supplementation effect of astaxanthin
on accommodation and asthenopia. Journal of Clinical Therapeutics Medicine, 22, 41–54.
Nakamura, M., Sugiura, M., & Aoki, N. (2006). High β-carotene and β-cryptoxanthin are associated
with low pulse wave velocity. Atherosclerosis, 184, 363–369.
Nakazawa, Y., Sashima, T., Hosokawa, M., & Miyashita, K. (2009). Comparative evaluation of
growth inhibitory effect of stereoisomers of fucoxanthin in human cancer cell lines. Journal of
Functional Foods, 1, 88–97.
Narisawa, T., Fukaura, Y., Hasebe, M., Nomura, S., Oshima, S., & Inakuma, T. (2000). Prevention of
N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin
and capsanthin-rich paprika juice. Proceedings of the Society for Experimental Biology and
Medicine, 224, 116–122.
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., et al. (1996).
Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease.
The New England Journal of Medicine, 334, 1150–1155.
Ono, M., Honda, M., Yasuda, K., Kanda, H., & Goto, M. (2018). Production of β-carotene
nanosuspensions using supercritical CO 2 and improvement of its efficiency by Z-isomerization
pre-treatment. Journal of Supercritical Fluids, 138, 124–131.
Østerlie, M., Bjerkeng, B., & Liaaen-Jensen, S. (2000). Plasma appearance and distribution of
astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration
of astaxanthin. Journal of Nutritional Biochemistry, 11, 482–490.
Ouchi, A., Aizawa, K., Iwasaki, Y., Inakuma, T., Terao, J., Nagaoka, S. I., et al. (2010). Kinetic study
of the quenching reaction of singlet oxygen by carotenoids and food extracts in solution. Development of a singlet oxygen absorption capacity (SOAC) assay method. Journal of Agriculture
and Food Chemistry, 58, 9967–9978.
Palozza, P., Parrone, N., Simone, R. E., & Catalano, A. (2010). Lycopene in atherosclerosis prevention: An integrated scheme of the potential mechanisms of action from cell culture studies.
Archives of Biochemistry and Biophysics, 504, 26–33.
Palozza, P., Torelli, C., Boninsegna, A., Simone, R., Catalano, A., Mele, M. C., et al. (2009). Growthinhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer
cells. Cancer Letters, 283, 108–117.
Perry, A., Rasmussen, H., & Johnson, E. J. (2009). Xanthophyll (lutein, zeaxanthin) content in
fruits, vegetables and corn and egg products. Journal of Food Composition and Analysis, 22,
9–15.
Rahman, S. O., Panda, B. P., Parvez, S., Kaundal, M., Hussain, S., Akhtar, M., et al. (2019).
Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in
animal model of Alzheimer’s disease. Biomedicine & Pharmacotherapy, 110, 47–58.
Rammuni, M. N., Ariyadasa, T. U., Nimarshana, P. H. V., & Attalage, R. A. (2019). Comparative assessment on the extraction of carotenoids from microalgal sources: Astaxanthin from H.
pluvialis and β-carotene from D. salina. Food Chemistry, 277, 128–134.
Relevy, N. Z., Rühl, R., Harari, A., Grosskopf, I., Barshack, I., Ben-Amotz, A., et al. (2015). 9-cis
β-Carotene inhibits atherosclerosis development in female LDLR-/-Mice. Functional Foods in
Health and Disease, 5, 67–79.
Roberts, R. L., Green, J., & Lewis, B. (2009). Lutein and zeaxanthin in eye and skin health. Clinics
in Dermatology, 27, 195–201.
Sachindra, N. M., Sato, E., Maeda, H., Hosokawa, M., Niwano, Y., Kohno, M., et al. (2007).
Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and
its metabolites. Journal of Agriculture and Food Chemistry, 55, 8516–8522.
Shirakura, Y., Takayanagi, K., Mukai, K., Tanabe, H., & Inoue, M. (2011). β-Cryptoxanthin
suppresses the adipogenesis of 3T3-L1 cells via RAR activation. Journal of Nutritional Science
and Vitaminology, 57, 426–431.