464
M. Honda
of a mixture of optical 3 and 3 R/S isomers of astaxanthin fatty acyl diesters. Comparative
Biochemistry and Physiology Part C: Toxicology & Pharmacology, 139, 99–110.
Darvin, M., Patzelt, A., Gehse, S., Schanzer, S., Benderoth, C., Sterry, W., et al. (2008). Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. European
Journal of Pharmaceutics and Biopharmaceutics, 69, 943–947.
Deming, D. M., Teixeira, S. R., & Erdman, J. W., Jr. (2002). All-trans β-carotene appears to be
more bioavailable than 9-cis or 13-cis β-carotene in gerbils given single oral doses of each isomer.
Journal of Nutrition, 132, 2700–2708.
Dhankhar, J., Kadian, S. S., & Sharma, A. (2012). Astaxanthin: A potential carotenoid. International
Journal of Pharmaceutical Sciences and Research, 3, 1246–1259.
Di Mascio, P., Kaiser, S., & Sies, H. (1989). Lycopene as the most efficient biological carotenoid
singlet oxygen quencher. Archives of Biochemistry and Biophysics, 274, 532–538.
D’Orazio, N., Gemello, E., Gammone, M., de Girolamo, M., Ficoneri, C., & Riccioni, G. (2012).
Fucoxantin: A treasure from the sea. Marine Drugs, 10, 604–616.
D’Odorico, A., Martines, D., Kiechl, S., Egger, G., Oberhollenzer, F., Bonvicini, P., et al. (2000).
High plasma levels of α-and β-carotene are associated with a lower risk of atherosclerosis: Results
from the Bruneck study. Atherosclerosis, 153, 231–239.
Druesne-Pecollo, N., Latino-Martel, P., Norat, T., Barrandon, E., Bertrais, S., Galan, P., et al. (2010).
β-carotene supplementation and cancer risk: A systematic review and metaanalysis of randomized
controlled trials. International Journal of Cancer, 127, 172–184.
During, A., Hussain, M. M., Morel, D. W., & Harrison, E. H. (2002). Carotenoid uptake and
secretion by CaCo-2 cells β-carotene isomer selectivity and carotenoid interactions. Journal of
Lipid Research, 43, 1086–1095.
Esatbeyoglu, T., & Rimbach, G. (2017). Canthaxanthin: From molecule to function. Molecular
Nutrition & Food Research, 61, 1600469.
Etminan, M., Takkouche, B., & Caamano-Isorna, F. (2004). The role of tomato products and
lycopene in the prevention of prostate cancer: A meta-analysis of observational studies. Cancer
Epidemiology, Biomarkers & Prevention, 13, 340–345.
Folman, Y., Ascarelli, I., Kraus, D., & Barash, H. (1987). Adverse effect of β-carotene in diet on
fertility of dairy cows. Journal of Dairy Science, 70, 357–366.
Gallicchio, L., Boyd, K., Matanoski, G., Tao, X., Chen, L., Lam, T. K., et al. (2008). Carotenoids and
the risk of developing lung cancer: A systematic review. American Journal of Clinical Nutrition,
88, 372–383.
Ganesan, P., Matsubara, K., Sugawara, T., & Hirata, T. (2013). Marine algal carotenoids inhibit
angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial
cells. Molecular and Cellular Biochemistry, 380, 1–9.
Ganesan, P., Noda, K., Manabe, Y., Ohkubo, T., Tanaka, Y., Maoka, T., et al. (2011). Siphonaxanthin,
a marine carotenoid from green algae, effectively induces apoptosis in human leukemia (HL-60)
cells. Biochimica et Biophysica Acta, 1810, 497–503.
Gaziano, J. M., Johnson, E. J., Russell, R. M., Manson, J. E., Stampfer, M. J., Ridker, P. M., et al.
(1995). Discrimination in absorption or transport of β-carotene isomers after oral supplementation
with either all-trans-or 9-cis-β-carotene. American Journal of Clinical Nutrition, 61, 1248–1252.
Hama, S., Takahashi, K., Inai, Y., Shiota, K., Sakamoto, R., Yamada, A., et al. (2012). Protective
effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation
on ultraviolet-induced skin damage. Journal of Pharmaceutical Sciences, 101, 2909–2916.
Harari, A., Harats, D., Marko, D., Cohen, H., Barshack, I., Kamari, Y., et al. (2008). A 9-cis βcarotene–enriched diet inhibits atherogenesis and fatty liver formation in LDL receptor knockout
mice. Journal of Nutrition, 138, 1923–1930.
Honda, M., Kodama, T., Kageyama, H., Hibino, T., Wahyudiono, Kanda, H., & Goto, M. (2018a).
Enhanced solubility and reduced crystallinity of carotenoids, β-carotene and astaxanthin, by
Z-isomerization. The European Journal of Lipid Science and Technology, 120(1800191), 1–8.
Honda, M., Murakami, K., Watanabe, Y., Higashiura, T., Fukaya, T., Wahyudiono, Kanda, H., &
Goto, M. (2017a). The E/Z isomer ratio of lycopene in foods and effect of heating with edible
M. Honda
of a mixture of optical 3 and 3 R/S isomers of astaxanthin fatty acyl diesters. Comparative
Biochemistry and Physiology Part C: Toxicology & Pharmacology, 139, 99–110.
Darvin, M., Patzelt, A., Gehse, S., Schanzer, S., Benderoth, C., Sterry, W., et al. (2008). Cutaneous concentration of lycopene correlates significantly with the roughness of the skin. European
Journal of Pharmaceutics and Biopharmaceutics, 69, 943–947.
Deming, D. M., Teixeira, S. R., & Erdman, J. W., Jr. (2002). All-trans β-carotene appears to be
more bioavailable than 9-cis or 13-cis β-carotene in gerbils given single oral doses of each isomer.
Journal of Nutrition, 132, 2700–2708.
Dhankhar, J., Kadian, S. S., & Sharma, A. (2012). Astaxanthin: A potential carotenoid. International
Journal of Pharmaceutical Sciences and Research, 3, 1246–1259.
Di Mascio, P., Kaiser, S., & Sies, H. (1989). Lycopene as the most efficient biological carotenoid
singlet oxygen quencher. Archives of Biochemistry and Biophysics, 274, 532–538.
D’Orazio, N., Gemello, E., Gammone, M., de Girolamo, M., Ficoneri, C., & Riccioni, G. (2012).
Fucoxantin: A treasure from the sea. Marine Drugs, 10, 604–616.
D’Odorico, A., Martines, D., Kiechl, S., Egger, G., Oberhollenzer, F., Bonvicini, P., et al. (2000).
High plasma levels of α-and β-carotene are associated with a lower risk of atherosclerosis: Results
from the Bruneck study. Atherosclerosis, 153, 231–239.
Druesne-Pecollo, N., Latino-Martel, P., Norat, T., Barrandon, E., Bertrais, S., Galan, P., et al. (2010).
β-carotene supplementation and cancer risk: A systematic review and metaanalysis of randomized
controlled trials. International Journal of Cancer, 127, 172–184.
During, A., Hussain, M. M., Morel, D. W., & Harrison, E. H. (2002). Carotenoid uptake and
secretion by CaCo-2 cells β-carotene isomer selectivity and carotenoid interactions. Journal of
Lipid Research, 43, 1086–1095.
Esatbeyoglu, T., & Rimbach, G. (2017). Canthaxanthin: From molecule to function. Molecular
Nutrition & Food Research, 61, 1600469.
Etminan, M., Takkouche, B., & Caamano-Isorna, F. (2004). The role of tomato products and
lycopene in the prevention of prostate cancer: A meta-analysis of observational studies. Cancer
Epidemiology, Biomarkers & Prevention, 13, 340–345.
Folman, Y., Ascarelli, I., Kraus, D., & Barash, H. (1987). Adverse effect of β-carotene in diet on
fertility of dairy cows. Journal of Dairy Science, 70, 357–366.
Gallicchio, L., Boyd, K., Matanoski, G., Tao, X., Chen, L., Lam, T. K., et al. (2008). Carotenoids and
the risk of developing lung cancer: A systematic review. American Journal of Clinical Nutrition,
88, 372–383.
Ganesan, P., Matsubara, K., Sugawara, T., & Hirata, T. (2013). Marine algal carotenoids inhibit
angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial
cells. Molecular and Cellular Biochemistry, 380, 1–9.
Ganesan, P., Noda, K., Manabe, Y., Ohkubo, T., Tanaka, Y., Maoka, T., et al. (2011). Siphonaxanthin,
a marine carotenoid from green algae, effectively induces apoptosis in human leukemia (HL-60)
cells. Biochimica et Biophysica Acta, 1810, 497–503.
Gaziano, J. M., Johnson, E. J., Russell, R. M., Manson, J. E., Stampfer, M. J., Ridker, P. M., et al.
(1995). Discrimination in absorption or transport of β-carotene isomers after oral supplementation
with either all-trans-or 9-cis-β-carotene. American Journal of Clinical Nutrition, 61, 1248–1252.
Hama, S., Takahashi, K., Inai, Y., Shiota, K., Sakamoto, R., Yamada, A., et al. (2012). Protective
effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation
on ultraviolet-induced skin damage. Journal of Pharmaceutical Sciences, 101, 2909–2916.
Harari, A., Harats, D., Marko, D., Cohen, H., Barshack, I., Kamari, Y., et al. (2008). A 9-cis βcarotene–enriched diet inhibits atherogenesis and fatty liver formation in LDL receptor knockout
mice. Journal of Nutrition, 138, 1923–1930.
Honda, M., Kodama, T., Kageyama, H., Hibino, T., Wahyudiono, Kanda, H., & Goto, M. (2018a).
Enhanced solubility and reduced crystallinity of carotenoids, β-carotene and astaxanthin, by
Z-isomerization. The European Journal of Lipid Science and Technology, 120(1800191), 1–8.
Honda, M., Murakami, K., Watanabe, Y., Higashiura, T., Fukaya, T., Wahyudiono, Kanda, H., &
Goto, M. (2017a). The E/Z isomer ratio of lycopene in foods and effect of heating with edible