8 Analytical Protocols in Phycobiliproteins Analysis
187
Table 8.1
(continued)
Disorder/disease model system PBP source
PBP activity
Experimental approach
References
Oxalate-induced renal injury
(Wistar rats)
PC
Nephroprotective
Histopathology, oxalate content
and lipid peroxidation of renal
tissues, stone forming,
biochemical analysis of urine
Farooq et al. (2004)
Thioacetamide-induced hepatic
encephalopathy (Wistar rats)
PC
Hepatoprotective
Levels of NH
3 in serum, liver,
and brain; prothrombin time and
albumin levels in plasma; lipid
peroxidation, Trp, antioxidant
enzymes activity in the brain;
histopathology and electron
microscopy of brain tissue
Sathyasaikumar et al.
(2007)
CCl
4 and
R-(+)-pulegone-induced
hepatotoxicity (Albino rats)
PC
Hepatoprotective
Serum GPT activity; liver
microsomal cytochrome P450,
glucose-6-phosphatase,
aminopyrine-N- demethylase
activities
Vadiraja et al. (1998)
Atherogenic diet-induced
oxidative stress (Golden Syrian
hamsters)
PC
Antihyperlipidemic and
antioxidative
Plasma lipid concentrations and
antioxidant capacity; liver
antioxidant enzymes activity;
aortic fatty streak area; cardiac
superoxide anion production
and expression of NADPH
oxidase
Riss et al. (2007)
(continued)
187
Table 8.1
(continued)
Disorder/disease model system PBP source
PBP activity
Experimental approach
References
Oxalate-induced renal injury
(Wistar rats)
PC
Nephroprotective
Histopathology, oxalate content
and lipid peroxidation of renal
tissues, stone forming,
biochemical analysis of urine
Farooq et al. (2004)
Thioacetamide-induced hepatic
encephalopathy (Wistar rats)
PC
Hepatoprotective
Levels of NH
3 in serum, liver,
and brain; prothrombin time and
albumin levels in plasma; lipid
peroxidation, Trp, antioxidant
enzymes activity in the brain;
histopathology and electron
microscopy of brain tissue
Sathyasaikumar et al.
(2007)
CCl
4 and
R-(+)-pulegone-induced
hepatotoxicity (Albino rats)
PC
Hepatoprotective
Serum GPT activity; liver
microsomal cytochrome P450,
glucose-6-phosphatase,
aminopyrine-N- demethylase
activities
Vadiraja et al. (1998)
Atherogenic diet-induced
oxidative stress (Golden Syrian
hamsters)
PC
Antihyperlipidemic and
antioxidative
Plasma lipid concentrations and
antioxidant capacity; liver
antioxidant enzymes activity;
aortic fatty streak area; cardiac
superoxide anion production
and expression of NADPH
oxidase
Riss et al. (2007)
(continued)
