188
M. R. Nikolic et al.
Table 8.1
(continued)
Disorder/disease model system PBP source
PBP activity
Experimental approach
References
Hypercholesterolemic
diet-induced hyperlipidemia
and oxidative stress (Golden
Syrian hamsters)
PC
Antihyperlipidemic and
antioxidative
Plasma lipid concentrations,
GOT/GPT activity and lipid
peroxidation in serum;
antioxidant enzymes activity in
the liver; mRNA levels of LDL
receptor, HMG-CoA reductase
of HepG2 cells
Sheu et al. (2013)
Selenite-induced
cataractogenesis (Wistar rat)
PC
Anticataractogenic
Antioxidant enzymes activity,
lipid peroxidation, and
glutathione lens tissue levels
Kumari et al. (2013)
Encephalitogen-induced
autoimmune encephalomyelitis
(Lewis rats)
C-PC/PCB
Anti-multiple sclerosis
Balance and motor
coordination; oxidative stress
markers in brain and serum;
cytokine levels in the brain;
electron microscopy of brain
tissue
Cervantes-Llanos et al.
(2018)
In vitro
Colon cancer SW480 cells
PE
Anti-cancer
Cell viability, cycle and
apoptosis assays; electron
microscopy; proteomics
analysis of cell lysate; assays
for signaling pathways involved
in cell death
Li et al. (2016)
(continued)