5 Retinoic Acid Signaling and Heart Development
147
Saremi F, Ho SY, Cabrera JA, Sánchez-Quintana D (2013) Right Ventricular Outflow Tract Imaging
With CT and MRI: Part 1. Morphology. Am J Roentgenol. 200:W39–W50. https://doi.org/10.
2214/AJR.12.9333
Schilling TF, Nie Q, Lander AD (2012) Dynamics and precision in retinoic acid morphogen
gradients. Curr Opin Genet Dev 22:562–569. https://doi.org/10.1016/j.gde.2012.11.012
Schoenebeck JJ, Keegan BR, Yelon D (2007) Vessel and Blood Specification Override Cardiac
Potential in Anterior Mesoderm. Dev Cell 13:254–267. https://doi.org/10.1016/j.devcel.2007.
05.012
Shimozono S, Iimura T, Kitaguchi T, Higashijima S-I, Miyawaki A (2013) Visualization of an
endogenous retinoic acid gradient across embryonic development. Nature 496:363–6. https://doi.
org/10.1038/nature12037
Sirbu IO, Zhao X, Duester G (2008) Retinoic acid controls heart anteroposterior patterning by downregulatingIsl1 through theFgf8 pathway. Dev Dyn 237:1627–1635. https://doi.org/10.1002/dvdy.
21570
Sive HL, Draper BW, Harland RM, Weintraub H (1990) Identification of a retinoic acid-sensitive
period during primary axis formation in Xenopus laevis. Genes Dev 4:932–42
Skene PJ, Henikoff JG, Henikoff S (2018) Targeted in situ genome-wide profiling with high
efficiency for low cell numbers. Nat Protoc 13:1006–1019. https://doi.org/10.1038/nprot.
2018.015
Sorrell MRJ, Waxman JS (2011) Restraint of Fgf8 signaling by retinoic acid signaling is required
for proper heart and forelimb formation. Dev Biol 358:44–55. https://doi.org/10.1016/j.ydbio.
2011.07.022
Sosnik J, Zheng L, Rackauckas CV, Digman M, Gratton E, Nie Q, Schilling TF (2016) Noise
modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the
embryonic zebrafish hindbrain. Elife. 5:e14034. https://doi.org/10.7554/eLife.14034
Srivastava D (2006) Making or Breaking the Heart: From Lineage Determination to Morphogenesis.
Cell 126:1037–1048. https://doi.org/10.1016/j.cell.2006.09.003
Stainier DYR, Fishman MC (1992) Patterning the zebrafish heart tube: Acquisition of anteroposterior polarity. Dev Biol 153:91–101. https://doi.org/10.1016/0012-1606(92)90094-W
Staudt D, Stainier D (2012) Uncovering the Molecular and Cellular Mechanisms of Heart Development Using the Zebrafish. Annu Rev Genet 46:397–418. https://doi.org/10.1146/annurev-genet110711-155646
Stefanovic S, Zaffran S (2017) Mechanisms of retinoic acid signaling during cardiogenesis. Mech
Dev 143:9–19. https://doi.org/10.1016/j.mod.2016.12.002
Stuckmann I, Evans S, Lassar AB (2003) Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation. Dev Biol 255:334–349. https://doi.org/
10.1016/S0012-1606(02)00078-7
Sucov HM, Dyson E, Gumeringer CL, Price J, Chien KR, Evans RM (1994) RXR alpha mutant mice
establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev 8:1007–18.
https://doi.org/10.1101/GAD.8.9.1007
Tanay A, Regev A (2017) Scaling single-cell genomics from phenomenology to mechanism. Nature
541:331–338. https://doi.org/10.1038/nature21350
Théveniau-Ruissy M, Dandonneau M, Mesbah K, Ghez O, Mattei M-G, Miquerol L, Kelly RG.
The del22q11.2 Candidate Gene Tbx1 Controls Regional Outflow Tract Identity and Coronary
Artery Patterning. Circ Res. 2008; 103:142–148. https://doi.org/10.1161/circresaha.108.172189
Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P, Sakai Y (2007) CYP26A1 and
CYP26C1 cooperatively regulate anterior–posterior patterning of the developing brain and the
production of migratory cranial neural crest cells in the mouse. Dev Biol 302:399–411. https://
doi.org/10.1016/j.ydbio.2006.09.045
van der Wees J, Matharu PJ, de Roos K, Destre´e OHJ, Godsave SF, Durston AJ, Sweeney GE.
Developmental expression and differential regulation by retinoic acid of Xenopus COUP-TF-A
and COUP-TF-B. Mech Dev. 1996; 54:173–184. https://doi.org/10.1016/0925-4773(95)00471-8
147
Saremi F, Ho SY, Cabrera JA, Sánchez-Quintana D (2013) Right Ventricular Outflow Tract Imaging
With CT and MRI: Part 1. Morphology. Am J Roentgenol. 200:W39–W50. https://doi.org/10.
2214/AJR.12.9333
Schilling TF, Nie Q, Lander AD (2012) Dynamics and precision in retinoic acid morphogen
gradients. Curr Opin Genet Dev 22:562–569. https://doi.org/10.1016/j.gde.2012.11.012
Schoenebeck JJ, Keegan BR, Yelon D (2007) Vessel and Blood Specification Override Cardiac
Potential in Anterior Mesoderm. Dev Cell 13:254–267. https://doi.org/10.1016/j.devcel.2007.
05.012
Shimozono S, Iimura T, Kitaguchi T, Higashijima S-I, Miyawaki A (2013) Visualization of an
endogenous retinoic acid gradient across embryonic development. Nature 496:363–6. https://doi.
org/10.1038/nature12037
Sirbu IO, Zhao X, Duester G (2008) Retinoic acid controls heart anteroposterior patterning by downregulatingIsl1 through theFgf8 pathway. Dev Dyn 237:1627–1635. https://doi.org/10.1002/dvdy.
21570
Sive HL, Draper BW, Harland RM, Weintraub H (1990) Identification of a retinoic acid-sensitive
period during primary axis formation in Xenopus laevis. Genes Dev 4:932–42
Skene PJ, Henikoff JG, Henikoff S (2018) Targeted in situ genome-wide profiling with high
efficiency for low cell numbers. Nat Protoc 13:1006–1019. https://doi.org/10.1038/nprot.
2018.015
Sorrell MRJ, Waxman JS (2011) Restraint of Fgf8 signaling by retinoic acid signaling is required
for proper heart and forelimb formation. Dev Biol 358:44–55. https://doi.org/10.1016/j.ydbio.
2011.07.022
Sosnik J, Zheng L, Rackauckas CV, Digman M, Gratton E, Nie Q, Schilling TF (2016) Noise
modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the
embryonic zebrafish hindbrain. Elife. 5:e14034. https://doi.org/10.7554/eLife.14034
Srivastava D (2006) Making or Breaking the Heart: From Lineage Determination to Morphogenesis.
Cell 126:1037–1048. https://doi.org/10.1016/j.cell.2006.09.003
Stainier DYR, Fishman MC (1992) Patterning the zebrafish heart tube: Acquisition of anteroposterior polarity. Dev Biol 153:91–101. https://doi.org/10.1016/0012-1606(92)90094-W
Staudt D, Stainier D (2012) Uncovering the Molecular and Cellular Mechanisms of Heart Development Using the Zebrafish. Annu Rev Genet 46:397–418. https://doi.org/10.1146/annurev-genet110711-155646
Stefanovic S, Zaffran S (2017) Mechanisms of retinoic acid signaling during cardiogenesis. Mech
Dev 143:9–19. https://doi.org/10.1016/j.mod.2016.12.002
Stuckmann I, Evans S, Lassar AB (2003) Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation. Dev Biol 255:334–349. https://doi.org/
10.1016/S0012-1606(02)00078-7
Sucov HM, Dyson E, Gumeringer CL, Price J, Chien KR, Evans RM (1994) RXR alpha mutant mice
establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev 8:1007–18.
https://doi.org/10.1101/GAD.8.9.1007
Tanay A, Regev A (2017) Scaling single-cell genomics from phenomenology to mechanism. Nature
541:331–338. https://doi.org/10.1038/nature21350
Théveniau-Ruissy M, Dandonneau M, Mesbah K, Ghez O, Mattei M-G, Miquerol L, Kelly RG.
The del22q11.2 Candidate Gene Tbx1 Controls Regional Outflow Tract Identity and Coronary
Artery Patterning. Circ Res. 2008; 103:142–148. https://doi.org/10.1161/circresaha.108.172189
Uehara M, Yashiro K, Mamiya S, Nishino J, Chambon P, Dolle P, Sakai Y (2007) CYP26A1 and
CYP26C1 cooperatively regulate anterior–posterior patterning of the developing brain and the
production of migratory cranial neural crest cells in the mouse. Dev Biol 302:399–411. https://
doi.org/10.1016/j.ydbio.2006.09.045
van der Wees J, Matharu PJ, de Roos K, Destre´e OHJ, Godsave SF, Durston AJ, Sweeney GE.
Developmental expression and differential regulation by retinoic acid of Xenopus COUP-TF-A
and COUP-TF-B. Mech Dev. 1996; 54:173–184. https://doi.org/10.1016/0925-4773(95)00471-8