21. Gong M, Bassi A (2016) Carotenoids from microalgae: a review of recent developments.
Biotechnol Adv 34(8):1396–1412
22. Guedes AC, Amaro HM, Malcata FX (2011) Microalgae as sources of carotenoids. Mar Drugs 9
(4):625–644
23. Michalak I, Chojnacka K (2014) Algal extracts: technology and advances. Eng Life Sci 14
(6):581–591
24. Michalak I, Chojnacka K (2014) Review. Algal extracts: technology and advances. Eng Life Sci
14:581–591
25. Hosikian A, Lim S, Halim R, Danquah MK (2010) Chlorophyll extraction from microalgae: a
review on the process engineering aspects. Int J Chem Eng 2010. https://doi.org/10.1155/2010/
391632
26. Kadam SU, Tiwari BK, O’Donnell CP (2013) Application of novel extraction technologies for
bioactives from marine algae. J Agric Food Chem 61(20):4667–4675
27. Moreau D, Tomasoni C, Jacquot C, Kaas R, Le Guedes R, Cadoret JP, Muller-Feuga A,
Kontiza I, Vagias C, Roussis V, Roussakis C (2006) Cultivated microalgae and the carotenoid
fucoxanthin from Odontella aurita as potent anti-proliferative agents in bronchopulmonary and
epithelial cell lines. Environ Toxicol Pharmacol 22(1):97–103
28. Ito N, Hirose M (1989) Antioxidants-carcinogenic and chemopreventive properties. Adv
Cancer Res 53:247–302
29. Gupta S, Abu-Ghannam N (2011) Recent developments in the application of seaweeds or
seaweed extracts as a means for enhancing the safety and quality attributes of foods. Innov Food
Sci Emerg Technol 12(4):600–609
30. Lee SH, Jeon YJ (2013) Anti-diabetic effects of brown algae derived phlorotannins, marine
polyphenols through diverse mechanisms. Fitoterapia 86:129–136
31. Yoshie Y, Wang W, Petillo D, Suzuki T (2000) Distribution of catechins in Japanese seaweeds.
Fish Sci 66(5):998–1000
32. Yuan YV, Bone DE, Carrington MF (2005) Antioxidant activity of dulse (Palmaria palmata)
extract evaluated in vitro. Food Chem 91(3):485–494
33. Duval B, Shetty K, Thomas WH (1999) Phenolic compounds and antioxidant properties in the
snow alga Chlamydomonas nivalis after exposure to UV light. J Appl Phycol 11(6):559
34. Becker W (2004) 18 Microalgae in human and animal nutrition. In: Amos R (ed) Handbook of
microalgal culture: biotechnology and applied phycology, vol 312. Wiley Online library
35. Running JA, Severson DK, Schneider KJ (2002) Extracellular production of L-ascorbic acid by
Chlorella protothecoides, Prototheca species, and mutants of P. moriformis during aerobic
culturing at low pH. J Ind Microbiol Biotechnol 29(2):93–98
36. Babu B, Wu JT (2008) Production of natural butylated hydroxytoluene as an antioxidant by
freshwater phytoplankton 1. J Phycol 44(6):1447–1454
37. Chojnacka K, Saeid A, Witkowska Z, Tuhy L (2012) Biologically active compounds in
seaweed extracts-the prospects for the application. Open Conf Proc J 3(1):20–28
38. Simopoulos AP (1999) Essential fatty acids in health and chronic disease. Am J Clin Nutr 70
(3):560s–569s
39. Francavilla M, Colaianna M, Zotti M, Morgese MG, Trotta P, Tucci P, Schiavone S, Cuomo V,
Trabace L (2012) Extraction, characterization and in vivo neuromodulatory activity of phytosterols from microalga Dunaliella tertiolecta. Curr Med Chem 19(18):3058–3067
40. Foley PM, Beach ES, Zimmerman JB (2011) Algae as a source of renewable chemicals:
opportunities and challenges. Green Chem 13(6):1399–1405
41. Brentner LB, Eckelman MJ, Zimmerman JB (2011) Combinatorial life cycle assessment to
inform process design of industrial production of algal biodiesel. Environ Sci Technol 45
(16):7060–7067
42. Silva C, Soliman E, Cameron G, Fabiano LA, Seider WD, Dunlop EH, Coaldrake AK (2013)
Commercial-scale biodiesel production from algae. Ind Eng Chem Res 53(13):5311–5324
43. Becker EW (2007) Micro-algae as a source of protein. Biotechnol Adv 25(2):207–210
Applications and Efficacy of Exceptional Bioactive Compounds from Microalgae
173
Biotechnol Adv 34(8):1396–1412
22. Guedes AC, Amaro HM, Malcata FX (2011) Microalgae as sources of carotenoids. Mar Drugs 9
(4):625–644
23. Michalak I, Chojnacka K (2014) Algal extracts: technology and advances. Eng Life Sci 14
(6):581–591
24. Michalak I, Chojnacka K (2014) Review. Algal extracts: technology and advances. Eng Life Sci
14:581–591
25. Hosikian A, Lim S, Halim R, Danquah MK (2010) Chlorophyll extraction from microalgae: a
review on the process engineering aspects. Int J Chem Eng 2010. https://doi.org/10.1155/2010/
391632
26. Kadam SU, Tiwari BK, O’Donnell CP (2013) Application of novel extraction technologies for
bioactives from marine algae. J Agric Food Chem 61(20):4667–4675
27. Moreau D, Tomasoni C, Jacquot C, Kaas R, Le Guedes R, Cadoret JP, Muller-Feuga A,
Kontiza I, Vagias C, Roussis V, Roussakis C (2006) Cultivated microalgae and the carotenoid
fucoxanthin from Odontella aurita as potent anti-proliferative agents in bronchopulmonary and
epithelial cell lines. Environ Toxicol Pharmacol 22(1):97–103
28. Ito N, Hirose M (1989) Antioxidants-carcinogenic and chemopreventive properties. Adv
Cancer Res 53:247–302
29. Gupta S, Abu-Ghannam N (2011) Recent developments in the application of seaweeds or
seaweed extracts as a means for enhancing the safety and quality attributes of foods. Innov Food
Sci Emerg Technol 12(4):600–609
30. Lee SH, Jeon YJ (2013) Anti-diabetic effects of brown algae derived phlorotannins, marine
polyphenols through diverse mechanisms. Fitoterapia 86:129–136
31. Yoshie Y, Wang W, Petillo D, Suzuki T (2000) Distribution of catechins in Japanese seaweeds.
Fish Sci 66(5):998–1000
32. Yuan YV, Bone DE, Carrington MF (2005) Antioxidant activity of dulse (Palmaria palmata)
extract evaluated in vitro. Food Chem 91(3):485–494
33. Duval B, Shetty K, Thomas WH (1999) Phenolic compounds and antioxidant properties in the
snow alga Chlamydomonas nivalis after exposure to UV light. J Appl Phycol 11(6):559
34. Becker W (2004) 18 Microalgae in human and animal nutrition. In: Amos R (ed) Handbook of
microalgal culture: biotechnology and applied phycology, vol 312. Wiley Online library
35. Running JA, Severson DK, Schneider KJ (2002) Extracellular production of L-ascorbic acid by
Chlorella protothecoides, Prototheca species, and mutants of P. moriformis during aerobic
culturing at low pH. J Ind Microbiol Biotechnol 29(2):93–98
36. Babu B, Wu JT (2008) Production of natural butylated hydroxytoluene as an antioxidant by
freshwater phytoplankton 1. J Phycol 44(6):1447–1454
37. Chojnacka K, Saeid A, Witkowska Z, Tuhy L (2012) Biologically active compounds in
seaweed extracts-the prospects for the application. Open Conf Proc J 3(1):20–28
38. Simopoulos AP (1999) Essential fatty acids in health and chronic disease. Am J Clin Nutr 70
(3):560s–569s
39. Francavilla M, Colaianna M, Zotti M, Morgese MG, Trotta P, Tucci P, Schiavone S, Cuomo V,
Trabace L (2012) Extraction, characterization and in vivo neuromodulatory activity of phytosterols from microalga Dunaliella tertiolecta. Curr Med Chem 19(18):3058–3067
40. Foley PM, Beach ES, Zimmerman JB (2011) Algae as a source of renewable chemicals:
opportunities and challenges. Green Chem 13(6):1399–1405
41. Brentner LB, Eckelman MJ, Zimmerman JB (2011) Combinatorial life cycle assessment to
inform process design of industrial production of algal biodiesel. Environ Sci Technol 45
(16):7060–7067
42. Silva C, Soliman E, Cameron G, Fabiano LA, Seider WD, Dunlop EH, Coaldrake AK (2013)
Commercial-scale biodiesel production from algae. Ind Eng Chem Res 53(13):5311–5324
43. Becker EW (2007) Micro-algae as a source of protein. Biotechnol Adv 25(2):207–210
Applications and Efficacy of Exceptional Bioactive Compounds from Microalgae
173