MIAT, 409
Microarray, 487
MiDAC, 31
MIND4, 72
miRNA, 523
Mithramycin, 130
MIV-6R, 140
Mixed lineage leukaemia (MLL), 169, 181,
267, 272
MLL-menin disruptors, 140
MLL1–4, 129, 138, 344, 373–378
MLL-AF9, 209, 213
MM-102, 138
MM-589, 138
Mocetinostat, 14
Molecular docking, 455
Molecular modeling, 455
Monomethylated arginine (MMA), 159, 161,
165, 170, 183
MS012, 128
MS049, 184
MS351, 354
MS453, 145
MS2126, 300
MS2177, 145
MS7972, 299
MS37452, 354
Muscular atrophy, 19, 44, 57, 341, 363, 418
Myelodysplastic syndrome (MDS), 209, 262,
272
Myeloid translocation protein-8, Nervy, and
DEAF-1 (MYND) domain, 141
Myristoylethanolamide, 81
Myristoyllysine, 31
MYST, 98
N
Nahuoic acid A, 144
Nanatinostat, 8
Nanopore sequencing, 512
β-Naphthols, 64
Nasopharyngeal carcinoma, 96, 101, 134
Nexturastat A, 459
NgTET, 267
Nivolumab, 444
NK13650A/B, 110
Non-small cell lung carcinoma (NSCLC), 66,
101, 111, 201, 409, 412, 444
NSC663284, 146
Nucleoside analogues, 262, 277
NuRD, 31
Nusinersen (Spinraza), 419
O
Obesity, 20, 129, 171, 262
OICR-9429, 139
Olaparib, 75
Oleoylethanolamide, 81
OTX-015, 302
Ovarian carcinomas, 96, 101, 178, 358, 410,
414
Oxadiazole-carbonylaminothiourea, 72
Oxazolopyridines, 77
2-Oxoglutarate (2OG)-dependent oxygenases,
221
P
p53, 5, 44, 46, 60–67, 101, 126, 141–144, 165,
172, 178, 199, 201, 298–300, 357, 364,
412, 432
p300, 95–114, 292, 542
Paclitaxel, 130
Panax ginseng, 78
Pancreatic adenocarcinoma, 75
Panobinostat, 8, 9, 18, 19, 32, 213, 459, 460,
532
Pargyline, 204
Parkinson’s disease (PD), 20, 57, 71, 378, 464
PCAF, 101, 298
PCI-34051, 11
PCPA, 206
Peptide probes, 29
PFI-2, 140
PFI-3, 295
PHD domain, 339
Phenelzine, 205
4-Phenyl-2-thiazolylhydrazones, 111
N-Phthaloyl-L-tryptophan, 264
Pinometostat, 136
Pivanex, 15
PKF118-310, 473
Plant homeodomain (PHD) fingers, 342
Plasmodium berghei, 20
Plasmodium falciparum, 38
PLZF, 130
Polycomb-like complex (PCL), 356
Polymyxin B, 205
Posttranslational modification (PTM), 429
Pracinostat, 8
PRC2, 130–135, 350, 356, 374–381, 404–419
disruptors, 133
PRMT1, 165
PRMT2, 170
PRMT3, 172
PRMT4 (CARM1), 467
Index
565
Microarray, 487
MiDAC, 31
MIND4, 72
miRNA, 523
Mithramycin, 130
MIV-6R, 140
Mixed lineage leukaemia (MLL), 169, 181,
267, 272
MLL-menin disruptors, 140
MLL1–4, 129, 138, 344, 373–378
MLL-AF9, 209, 213
MM-102, 138
MM-589, 138
Mocetinostat, 14
Molecular docking, 455
Molecular modeling, 455
Monomethylated arginine (MMA), 159, 161,
165, 170, 183
MS012, 128
MS049, 184
MS351, 354
MS453, 145
MS2126, 300
MS2177, 145
MS7972, 299
MS37452, 354
Muscular atrophy, 19, 44, 57, 341, 363, 418
Myelodysplastic syndrome (MDS), 209, 262,
272
Myeloid translocation protein-8, Nervy, and
DEAF-1 (MYND) domain, 141
Myristoylethanolamide, 81
Myristoyllysine, 31
MYST, 98
N
Nahuoic acid A, 144
Nanatinostat, 8
Nanopore sequencing, 512
β-Naphthols, 64
Nasopharyngeal carcinoma, 96, 101, 134
Nexturastat A, 459
NgTET, 267
Nivolumab, 444
NK13650A/B, 110
Non-small cell lung carcinoma (NSCLC), 66,
101, 111, 201, 409, 412, 444
NSC663284, 146
Nucleoside analogues, 262, 277
NuRD, 31
Nusinersen (Spinraza), 419
O
Obesity, 20, 129, 171, 262
OICR-9429, 139
Olaparib, 75
Oleoylethanolamide, 81
OTX-015, 302
Ovarian carcinomas, 96, 101, 178, 358, 410,
414
Oxadiazole-carbonylaminothiourea, 72
Oxazolopyridines, 77
2-Oxoglutarate (2OG)-dependent oxygenases,
221
P
p53, 5, 44, 46, 60–67, 101, 126, 141–144, 165,
172, 178, 199, 201, 298–300, 357, 364,
412, 432
p300, 95–114, 292, 542
Paclitaxel, 130
Panax ginseng, 78
Pancreatic adenocarcinoma, 75
Panobinostat, 8, 9, 18, 19, 32, 213, 459, 460,
532
Pargyline, 204
Parkinson’s disease (PD), 20, 57, 71, 378, 464
PCAF, 101, 298
PCI-34051, 11
PCPA, 206
Peptide probes, 29
PFI-2, 140
PFI-3, 295
PHD domain, 339
Phenelzine, 205
4-Phenyl-2-thiazolylhydrazones, 111
N-Phthaloyl-L-tryptophan, 264
Pinometostat, 136
Pivanex, 15
PKF118-310, 473
Plant homeodomain (PHD) fingers, 342
Plasmodium berghei, 20
Plasmodium falciparum, 38
PLZF, 130
Polycomb-like complex (PCL), 356
Polymyxin B, 205
Posttranslational modification (PTM), 429
Pracinostat, 8
PRC2, 130–135, 350, 356, 374–381, 404–419
disruptors, 133
PRMT1, 165
PRMT2, 170
PRMT3, 172
PRMT4 (CARM1), 467
Index
565