Phenelzine
NHNH 2
Bizine
NHNH 2
N
H
O
N
H
N
H
N
H
N
H
N
H
N
H
N
H
Ph
NH
NH
N
H
Ph
Ph
NH NH
Ph
5
4
Ph
N
H
N
H
N
H
H
N
H
N
H
N
Ph
Ph
Ph
S
S
5
OH
H
N
O
NH 2
N OH
6
N
Me
NC
O
NH
7
Cl
OH
N
Me
N
H
O
S N
H
O O
SP2509
N
Me
NC
O
GSK-690
NH
NC
N
OMe
F
N
O
H
N
8
Me
O
Me
H
N
NH 2
O
N
H
Me
OH
H
O
H
N
N
H
O
NH 2
O
NH
H 2 N
O
N
H O
H
N
O
Me
Me
HN
NH 2
O
HN
O
NH 2
H
N
Me
H
HO
O
NH
O
O
HN
O
Me
N
H
O
N
S
Me
9
polymyxin B
N
N
O
O
Me
Me
HN
N
N
H
N
Me
Me
E11
Fig. 2 (continued)
Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors
205