9 Aptamers for the Diagnosis of Malign Tumors
275
127. Pu Y, Liu Z, Lu Y, Yuan P, Liu J, Yu B, Wang G, Yang CJ, Liu H, Tan W (2015) Using DNA
aptamer probe for immunostaining of cancer frozen tissues. Anal Chem 87(3):1919–1924
128. Li W-M, Bing T, Wei J-Y, Chen Z-Z, Shangguan D-H, Fang J (2014) Cell-SELEX-based
selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells.
Biomaterials 35(25):6998–7007
129. McDonnell LA, Angel PM, Lou S, Drake RR (2017) Mass spectrometry imaging in cancer
research: Future perspectives. Adv Cancer Res 134:283–290
130. Chen S, Xiong C, Liu H, Wan Q, Hou J, He Q, Badu-Tawiah A, Nie Z (2015) Mass spectrometry imaging reveals the sub-organ distribution of carbon nanomaterials. Nat Nanotechnol
10(2):176–182
131. Tseng YT, Harroun SG, Wu CW, Mao JY, Chang HT, Huang CC (2017) Satellitelike Gold Nanocomposites for Targeted Mass Spectrometry Imaging of Tumor Tissues.
Nanotheranostics 1(2):141–153
132. Yoon S, Rossi JJ (2018) Targeted Molecular Imaging Using Aptamers in Cancer. Pharmaceuticals 11(3):71
133. Weissleder R (1999) Molecular Imaging: Exploring the Next Frontier. Radiology 212(3):609–
614
134. Shi H, Tang Z, Kim Y, Nie H, Huang YF, He X, Deng K, Wang K, Tan W (2010) In vivo
fluorescence imaging of tumors using molecular aptamers generated by cell-SELEX. Chem
Asian J 5(10):2209–2213
135. Shi H, Cui W, He X, Guo Q, Wang K, Ye X, Tang J (2013) Whole cell-SELEX aptamers for
highly specific fluorescence molecular imaging of carcinomas in vivo. PLoS ONE 8(8):e70476
136. Dassie JP, Hernandez LI, Thomas GS, Long ME, Rockey WM, Howell CA, Chen Y, Hernandez
FJ, Liu XY, Wilson ME, Allen LA, Vaena DA, Meyerholz DK, Giangrande PH (2014) Targeted
inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane
antigen. Mol Ther 22(11):1910–1922
137. Chen H, Zhao J, Zhang M, Yang H, Ma Y, Gu Y (2015) MUC1 aptamer-based near-infrared
fluorescence probes for tumor imaging. Mol Imaging Biol 17(1):38–48
138. Zhang C, Ji X, Zhang Y, Zhou G, Ke X, Wang H, Tinnefeld P, He Z (2013) One-pot synthesized
aptamer-functionalized CdTe:Zn 2+ quantum dots for tumor-targeted fluorescence imaging
in vitro and in vivo. Anal Chem 85(12):5843–5849
139. Greenall SA, Donoghue JF, Van Sinderen M, Dubljevic V, Budiman S, Devlin M, Street I,
Adams TE, Johns TG (2015) EGFRvIII-mediated transactivation of receptor tyrosine kinases
in glioma: mechanism and therapeutic implications. Oncogene 34(41):5277–5287
140. Tang J, Huang N, Zhang X, Zhou T, Tan Y, Pi J, Pi L, Cheng S, Zheng H, Cheng Y (2017)
Aptamer-conjugated PEGylated quantum dots targeting epidermal growth factor receptor
variant III for fluorescence imaging of glioma. Int J Nanomedicine 12:3899–3911
141. Lim EK, Kim B, Choi Y, Ro Y, Cho EJ, Lee JH, Ryu SH, Suh JS, Haam S, Huh YM (2014)
Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin
alphavbeta3 via magnetic resonance imaging. J Biomed Mater Res A 102(1):49–59
142. Zhu H, Zhang L, Liu Y, Zhou Y, Wang K, Xie X, Song L, Wang D, Han C, Chen Q (2016)
Aptamer-PEG-modified Fe 3 O 4 @Mn as a novel T1- and T2- dual-model MRI contrast agent
targeting hypoxia-induced cancer stem cells. Sci Rep 6:39245
143. Kryza D, Debordeaux F, Azema L, Hassan A, Paurelle O, Schulz J, Savona-Baron C,
Charignon E, Bonazza P, Taleb J, Fernandez P, Janier M, Toulme JJ (2016) Ex vivo and
in vivo imaging and biodistribution of aptamers targeting the human matrix metalloprotease-9
in melanomas. PLoS ONE 11(2):e0149387
144. Wu X, Liang H, Tan Y, Yuan C, Li S, Li X, Li G, Shi Y, Zhang X (2014) Cell-SELEX
aptamer for highly specific radionuclide molecular imaging of glioblastoma in vivo. PLoS
ONE 9(6):e90752
145. Jacobson O, Weiss ID, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu
G, Kiesewetter DO, Vasdev N, Liang SH, Chen X (2015) 18 F-labeled single-stranded
DNA aptamer for PET imaging of protein tyrosine kinase-7 expression. J Nucl Med
56(11):1780–1785
275
127. Pu Y, Liu Z, Lu Y, Yuan P, Liu J, Yu B, Wang G, Yang CJ, Liu H, Tan W (2015) Using DNA
aptamer probe for immunostaining of cancer frozen tissues. Anal Chem 87(3):1919–1924
128. Li W-M, Bing T, Wei J-Y, Chen Z-Z, Shangguan D-H, Fang J (2014) Cell-SELEX-based
selection of aptamers that recognize distinct targets on metastatic colorectal cancer cells.
Biomaterials 35(25):6998–7007
129. McDonnell LA, Angel PM, Lou S, Drake RR (2017) Mass spectrometry imaging in cancer
research: Future perspectives. Adv Cancer Res 134:283–290
130. Chen S, Xiong C, Liu H, Wan Q, Hou J, He Q, Badu-Tawiah A, Nie Z (2015) Mass spectrometry imaging reveals the sub-organ distribution of carbon nanomaterials. Nat Nanotechnol
10(2):176–182
131. Tseng YT, Harroun SG, Wu CW, Mao JY, Chang HT, Huang CC (2017) Satellitelike Gold Nanocomposites for Targeted Mass Spectrometry Imaging of Tumor Tissues.
Nanotheranostics 1(2):141–153
132. Yoon S, Rossi JJ (2018) Targeted Molecular Imaging Using Aptamers in Cancer. Pharmaceuticals 11(3):71
133. Weissleder R (1999) Molecular Imaging: Exploring the Next Frontier. Radiology 212(3):609–
614
134. Shi H, Tang Z, Kim Y, Nie H, Huang YF, He X, Deng K, Wang K, Tan W (2010) In vivo
fluorescence imaging of tumors using molecular aptamers generated by cell-SELEX. Chem
Asian J 5(10):2209–2213
135. Shi H, Cui W, He X, Guo Q, Wang K, Ye X, Tang J (2013) Whole cell-SELEX aptamers for
highly specific fluorescence molecular imaging of carcinomas in vivo. PLoS ONE 8(8):e70476
136. Dassie JP, Hernandez LI, Thomas GS, Long ME, Rockey WM, Howell CA, Chen Y, Hernandez
FJ, Liu XY, Wilson ME, Allen LA, Vaena DA, Meyerholz DK, Giangrande PH (2014) Targeted
inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane
antigen. Mol Ther 22(11):1910–1922
137. Chen H, Zhao J, Zhang M, Yang H, Ma Y, Gu Y (2015) MUC1 aptamer-based near-infrared
fluorescence probes for tumor imaging. Mol Imaging Biol 17(1):38–48
138. Zhang C, Ji X, Zhang Y, Zhou G, Ke X, Wang H, Tinnefeld P, He Z (2013) One-pot synthesized
aptamer-functionalized CdTe:Zn 2+ quantum dots for tumor-targeted fluorescence imaging
in vitro and in vivo. Anal Chem 85(12):5843–5849
139. Greenall SA, Donoghue JF, Van Sinderen M, Dubljevic V, Budiman S, Devlin M, Street I,
Adams TE, Johns TG (2015) EGFRvIII-mediated transactivation of receptor tyrosine kinases
in glioma: mechanism and therapeutic implications. Oncogene 34(41):5277–5287
140. Tang J, Huang N, Zhang X, Zhou T, Tan Y, Pi J, Pi L, Cheng S, Zheng H, Cheng Y (2017)
Aptamer-conjugated PEGylated quantum dots targeting epidermal growth factor receptor
variant III for fluorescence imaging of glioma. Int J Nanomedicine 12:3899–3911
141. Lim EK, Kim B, Choi Y, Ro Y, Cho EJ, Lee JH, Ryu SH, Suh JS, Haam S, Huh YM (2014)
Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin
alphavbeta3 via magnetic resonance imaging. J Biomed Mater Res A 102(1):49–59
142. Zhu H, Zhang L, Liu Y, Zhou Y, Wang K, Xie X, Song L, Wang D, Han C, Chen Q (2016)
Aptamer-PEG-modified Fe 3 O 4 @Mn as a novel T1- and T2- dual-model MRI contrast agent
targeting hypoxia-induced cancer stem cells. Sci Rep 6:39245
143. Kryza D, Debordeaux F, Azema L, Hassan A, Paurelle O, Schulz J, Savona-Baron C,
Charignon E, Bonazza P, Taleb J, Fernandez P, Janier M, Toulme JJ (2016) Ex vivo and
in vivo imaging and biodistribution of aptamers targeting the human matrix metalloprotease-9
in melanomas. PLoS ONE 11(2):e0149387
144. Wu X, Liang H, Tan Y, Yuan C, Li S, Li X, Li G, Shi Y, Zhang X (2014) Cell-SELEX
aptamer for highly specific radionuclide molecular imaging of glioblastoma in vivo. PLoS
ONE 9(6):e90752
145. Jacobson O, Weiss ID, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu
G, Kiesewetter DO, Vasdev N, Liang SH, Chen X (2015) 18 F-labeled single-stranded
DNA aptamer for PET imaging of protein tyrosine kinase-7 expression. J Nucl Med
56(11):1780–1785