75. F. Chen, S. Goel, H.F. Valdovinos, H. Luo, R. Hernandez, T.E. Barnhart et al., In vivo
integrity and biological fate of chelator-free zirconium-89-labeled mesoporous silica
nanoparticles. ACS Nano 9, 7950–7959 (2015)
76. W. Cai, K. Chen, Z.B. Li, S.S. Gambhir, X. Chen, Dual-function probe for PET and
near-infrared fluorescence imaging of tumor vasculature. J. Nucl. Med. 48, 1862–1870 (2007)
77. W. Cai, D.W. Shin, K. Chen, O. Gheysens, Q. Cao, S.X. Wang et al., Peptide-labeled
near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett. 6,
669–676 (2006)
78. C. Kirchner, T. Liedl, S. Kudera, T. Pellegrino, A. Munoz Javier, H.E. Gaub et al.,
Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles. Nano Lett. 5, 331–338 (2005)
79. S.W. Zielhuis, J.H. Seppenwoolde, V.A. Mateus, C.J. Bakker, G.C. Krijger, G. Storm et al.,
Lanthanide-loaded liposomes for multimodality imaging and therapy. Cancer Biother.
Radiopharm. 21, 520–527 (2006)
80. Z. Medarova, W. Pham, C. Farrar, V. Petkova, A. Moore, In vivo imaging of siRNA delivery
and silencing in tumors. Nat. Med. 13, 372–377 (2007)
81. C.C. Mello, D. Conte Jr., Revealing the world of RNA interference. Nature 431, 338–342
(2004)
82. A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, C.C. Mello, Potent and specific
genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806–
811 (1998)
83. M. Mae, U. Langel, Cell-penetrating peptides as vectors for peptide, protein and
oligonucleotide delivery. Curr. Opin. Pharmacol. 6, 509–514 (2006)
84. H. Hong, Y. Zhang, J. Sun, W. Cai, Molecular imaging and therapy of cancer with
radiolabeled nanoparticles. Nano Today 4, 399–413 (2009)
85. Y.I. Kim, S. Jeong, K.O. Jung, M.G. Song, C.H. Lee, S.J. Chung et al., Simultaneous
detection of EGFR and VEGF in colorectal cancer using Fluorescence-Raman Endoscopy.
Sci. Rep. 7, 1035 (2017)
86. J.L. Houghton, B.M. Zeglis, D. Abdel-Atti, R. Aggeler, R. Sawada, B.J. Agnew et al.,
Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and
multimodal PET/NIRF imaging of pancreatic cancer. Proc. Natl. Acad. Sci. U.S.A. 112,
15850–15855 (2015)
87. Y. Xing, J. Zhao, P.S. Conti, K. Chen, Radiolabeled nanoparticles for multimodality tumor
imaging. Theranostics 4, 290–306 (2014)
88. D.S. Lee, H.J. Im, Y.S. Lee, Radionanomedicine: widened perspectives of molecular
theragnosis. Nanomedicine 11, 795–810 (2015)
22 Molecular Imaging Using Radionanomedicine
429
integrity and biological fate of chelator-free zirconium-89-labeled mesoporous silica
nanoparticles. ACS Nano 9, 7950–7959 (2015)
76. W. Cai, K. Chen, Z.B. Li, S.S. Gambhir, X. Chen, Dual-function probe for PET and
near-infrared fluorescence imaging of tumor vasculature. J. Nucl. Med. 48, 1862–1870 (2007)
77. W. Cai, D.W. Shin, K. Chen, O. Gheysens, Q. Cao, S.X. Wang et al., Peptide-labeled
near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett. 6,
669–676 (2006)
78. C. Kirchner, T. Liedl, S. Kudera, T. Pellegrino, A. Munoz Javier, H.E. Gaub et al.,
Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles. Nano Lett. 5, 331–338 (2005)
79. S.W. Zielhuis, J.H. Seppenwoolde, V.A. Mateus, C.J. Bakker, G.C. Krijger, G. Storm et al.,
Lanthanide-loaded liposomes for multimodality imaging and therapy. Cancer Biother.
Radiopharm. 21, 520–527 (2006)
80. Z. Medarova, W. Pham, C. Farrar, V. Petkova, A. Moore, In vivo imaging of siRNA delivery
and silencing in tumors. Nat. Med. 13, 372–377 (2007)
81. C.C. Mello, D. Conte Jr., Revealing the world of RNA interference. Nature 431, 338–342
(2004)
82. A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, C.C. Mello, Potent and specific
genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806–
811 (1998)
83. M. Mae, U. Langel, Cell-penetrating peptides as vectors for peptide, protein and
oligonucleotide delivery. Curr. Opin. Pharmacol. 6, 509–514 (2006)
84. H. Hong, Y. Zhang, J. Sun, W. Cai, Molecular imaging and therapy of cancer with
radiolabeled nanoparticles. Nano Today 4, 399–413 (2009)
85. Y.I. Kim, S. Jeong, K.O. Jung, M.G. Song, C.H. Lee, S.J. Chung et al., Simultaneous
detection of EGFR and VEGF in colorectal cancer using Fluorescence-Raman Endoscopy.
Sci. Rep. 7, 1035 (2017)
86. J.L. Houghton, B.M. Zeglis, D. Abdel-Atti, R. Aggeler, R. Sawada, B.J. Agnew et al.,
Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and
multimodal PET/NIRF imaging of pancreatic cancer. Proc. Natl. Acad. Sci. U.S.A. 112,
15850–15855 (2015)
87. Y. Xing, J. Zhao, P.S. Conti, K. Chen, Radiolabeled nanoparticles for multimodality tumor
imaging. Theranostics 4, 290–306 (2014)
88. D.S. Lee, H.J. Im, Y.S. Lee, Radionanomedicine: widened perspectives of molecular
theragnosis. Nanomedicine 11, 795–810 (2015)
22 Molecular Imaging Using Radionanomedicine
429