15. H. Kim, L.R. Furenlid, M.J. Crawford, D.W. Wilson, H.B. Barber, T.E. Peterson et al.,
SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager
based on eight cadmium zinc telluride (CZT) detector arrays. Med. Phys. 33(2), 465–474
(2006)
16. H. Mahani, G. Raisali, A. Kamali-Asl, M.R. Ay, Spinning slithole collimation for
high-sensitivity small animal SPECT: Design and assessment using GATE simulation.
Phys. Med. 40, 42–50 (2017)
17. K. Ogawa, N. Ohmura, H. Iida, K. Nakamura, T. Nakahara, A. Kubo, Development of an
ultra-high resolution SPECT system with a CdTe semiconductor detector. Ann. Nucl. Med. 23
(8), 763–770 (2009)
18. S. Ben-Haim, K. Kacperski, S. Hain, D. Van Gramberg, B.F. Hutton, W.A. Waddington et al.,
Simultaneous dual-radionuclide myocardial perfusion imaging with a solid-state dedicated
cardiac camera. Eur. J. Nucl. Med. Mol. Med. 37(9), 1710–1721 (2010)
19. B. Carmen, V. Stefaan, Van H. Roel, Evaluation of a compact, high-resolution SPECT
detector based on digital silicon photomultipliers. Phys. Med. Biol. 59(23), 7521 (2014)
20. P. Busca, M. Occhipinti, P. Trigilio, G. Cozzi, C. Fiorini, C. Piemonte et al., Experimental
Evaluation of a SiPM-Based Scintillation Detector for MR-Compatible SPECT Systems.
IEEE Trans. Nucl. Sci. 62(5), 2122–2128 (2015)
21. H. Hwang, J. Kwon, P.S. Oh, T.K. Lee, K.S. Na, C.M. Lee et al., Peptide-loaded
nanoparticles and radionuclide imaging for individualized treatment of myocardial ischemia.
Radiology 273(1), 160–167 (2014)
22. S.H. Cheng, D. Yu, H.M. Tsai, R.A. Morshed, D. Kanojia, L.W. Lo et al., Dynamic in vivo
SPECT imaging of neural stem cells functionalized with radiolabeled nanoparticles for
tracking of glioblastoma. J. Nucl. Med. 57(2), 279–284 (2016)
23. M.C. Parrott, S.R. Benhabbour, C. Saab, J.A. Lemon, S. Parker, J.F. Valliant et al., Synthesis,
radiolabeling, and bio-imaging of high-generation polyester dendrimers. J. Am. Chem. Soc.
131(8), 2906–2916 (2009)
24. A. Chrastina, J.E. Schnitzer, Iodine-125 radiolabeling of silver nanoparticles for in vivo
SPECT imaging. Int. J. Nanomed. 5, 653–659 (2010)
25. R.R. Patil, J. Yu, S.R. Banerjee, Y. Ren, D. Leong, X. Jiang et al., Probing in vivo trafficking
of polymer/DNA micellar nanoparticles using SPECT/CT imaging. Mol. Ther. 19(9), 1626–
1635 (2011)
26. D. Jiang, Y. Sun, J. Li, Q. Li, M. Lv, B. Zhu et al., Multiple-armed tetrahedral DNA
nanostructures for tumor-targeting, dual-modality in vivo imaging. ACS Appl. Mater. Inter. 8
(7), 4378–4384 (2016)
27. R. Madru, P. Kjellman, F. Olsson, K. Wingardh, C. Ingvar, F. Stahlberg et al.,
99m Tc-labeled
superparamagnetic iron oxide nanoparticles for multimodality SPECT/MRI of sentinel lymph
nodes. J. Nucl. Med. 53(3), 459–463 (2012)
28. J. Wang, H. Zhao, Z. Zhou, P. Zhou, Y. Yan, M. Wang et al., MR/SPECT imaging guided
photothermal therapy of tumor-targeting Fe@Fe 3 O 4 nanoparticles in vivo with low
mononuclear phagocyte uptake. ACS Appl. Mater. Inter. 8(31), 19872–19882 (2016)
29. K.C.L. Black, W.J. Akers, G. Sudlow, B. Xu, R. Laforest, S. Achilefu, Dual-radiolabeled
nanoparticle SPECT probes for bioimaging. Nanoscale 7(2), 440–444 (2015)
30. D. Cheng, Y. Wang, X. Liu, P.H. Pretorius, M. Liang, M. Rusckowski et al., Comparison of
18
F PET and
99m
Tc SPECT imaging in phantoms and in tumored mice. Bioconjug. Chem. 21
(8), 1565–1570 (2010)
31. A.B. Satterlee, H. Yuan, L. Huang, A radio-theranostic nanoparticle with high specific drug
loading for cancer therapy and imaging. J. Control Release 217, 170–182 (2015)
32. S. Yook, Z. Cai, Y. Lu, M.A. Winnik, J.P. Pignol, R.M. Reilly, Intratumorally injected
177
Lu-labeled gold nanoparticles: Gold nanoseed brachytherapy with application for
neoadjuvant treatment of locally advanced breast cancer. J. Nucl. Med. 57(6), 936–942 (2016)
33. H. Ming, L. Fang, J. Gao, C. Li, Y. Ji, Y. Shen et al., Antitumor effect of nanoparticle
131
I-labeled arginine-glycine-aspartate–bovine serum albumin–polycaprolactone in lung
cancer. AJR Am. J. Roentgenol. 208(5), 1116–1126 (2017)
290
H.-J. Im and G. J. Cheon
SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager
based on eight cadmium zinc telluride (CZT) detector arrays. Med. Phys. 33(2), 465–474
(2006)
16. H. Mahani, G. Raisali, A. Kamali-Asl, M.R. Ay, Spinning slithole collimation for
high-sensitivity small animal SPECT: Design and assessment using GATE simulation.
Phys. Med. 40, 42–50 (2017)
17. K. Ogawa, N. Ohmura, H. Iida, K. Nakamura, T. Nakahara, A. Kubo, Development of an
ultra-high resolution SPECT system with a CdTe semiconductor detector. Ann. Nucl. Med. 23
(8), 763–770 (2009)
18. S. Ben-Haim, K. Kacperski, S. Hain, D. Van Gramberg, B.F. Hutton, W.A. Waddington et al.,
Simultaneous dual-radionuclide myocardial perfusion imaging with a solid-state dedicated
cardiac camera. Eur. J. Nucl. Med. Mol. Med. 37(9), 1710–1721 (2010)
19. B. Carmen, V. Stefaan, Van H. Roel, Evaluation of a compact, high-resolution SPECT
detector based on digital silicon photomultipliers. Phys. Med. Biol. 59(23), 7521 (2014)
20. P. Busca, M. Occhipinti, P. Trigilio, G. Cozzi, C. Fiorini, C. Piemonte et al., Experimental
Evaluation of a SiPM-Based Scintillation Detector for MR-Compatible SPECT Systems.
IEEE Trans. Nucl. Sci. 62(5), 2122–2128 (2015)
21. H. Hwang, J. Kwon, P.S. Oh, T.K. Lee, K.S. Na, C.M. Lee et al., Peptide-loaded
nanoparticles and radionuclide imaging for individualized treatment of myocardial ischemia.
Radiology 273(1), 160–167 (2014)
22. S.H. Cheng, D. Yu, H.M. Tsai, R.A. Morshed, D. Kanojia, L.W. Lo et al., Dynamic in vivo
SPECT imaging of neural stem cells functionalized with radiolabeled nanoparticles for
tracking of glioblastoma. J. Nucl. Med. 57(2), 279–284 (2016)
23. M.C. Parrott, S.R. Benhabbour, C. Saab, J.A. Lemon, S. Parker, J.F. Valliant et al., Synthesis,
radiolabeling, and bio-imaging of high-generation polyester dendrimers. J. Am. Chem. Soc.
131(8), 2906–2916 (2009)
24. A. Chrastina, J.E. Schnitzer, Iodine-125 radiolabeling of silver nanoparticles for in vivo
SPECT imaging. Int. J. Nanomed. 5, 653–659 (2010)
25. R.R. Patil, J. Yu, S.R. Banerjee, Y. Ren, D. Leong, X. Jiang et al., Probing in vivo trafficking
of polymer/DNA micellar nanoparticles using SPECT/CT imaging. Mol. Ther. 19(9), 1626–
1635 (2011)
26. D. Jiang, Y. Sun, J. Li, Q. Li, M. Lv, B. Zhu et al., Multiple-armed tetrahedral DNA
nanostructures for tumor-targeting, dual-modality in vivo imaging. ACS Appl. Mater. Inter. 8
(7), 4378–4384 (2016)
27. R. Madru, P. Kjellman, F. Olsson, K. Wingardh, C. Ingvar, F. Stahlberg et al.,
99m Tc-labeled
superparamagnetic iron oxide nanoparticles for multimodality SPECT/MRI of sentinel lymph
nodes. J. Nucl. Med. 53(3), 459–463 (2012)
28. J. Wang, H. Zhao, Z. Zhou, P. Zhou, Y. Yan, M. Wang et al., MR/SPECT imaging guided
photothermal therapy of tumor-targeting Fe@Fe 3 O 4 nanoparticles in vivo with low
mononuclear phagocyte uptake. ACS Appl. Mater. Inter. 8(31), 19872–19882 (2016)
29. K.C.L. Black, W.J. Akers, G. Sudlow, B. Xu, R. Laforest, S. Achilefu, Dual-radiolabeled
nanoparticle SPECT probes for bioimaging. Nanoscale 7(2), 440–444 (2015)
30. D. Cheng, Y. Wang, X. Liu, P.H. Pretorius, M. Liang, M. Rusckowski et al., Comparison of
18
F PET and
99m
Tc SPECT imaging in phantoms and in tumored mice. Bioconjug. Chem. 21
(8), 1565–1570 (2010)
31. A.B. Satterlee, H. Yuan, L. Huang, A radio-theranostic nanoparticle with high specific drug
loading for cancer therapy and imaging. J. Control Release 217, 170–182 (2015)
32. S. Yook, Z. Cai, Y. Lu, M.A. Winnik, J.P. Pignol, R.M. Reilly, Intratumorally injected
177
Lu-labeled gold nanoparticles: Gold nanoseed brachytherapy with application for
neoadjuvant treatment of locally advanced breast cancer. J. Nucl. Med. 57(6), 936–942 (2016)
33. H. Ming, L. Fang, J. Gao, C. Li, Y. Ji, Y. Shen et al., Antitumor effect of nanoparticle
131
I-labeled arginine-glycine-aspartate–bovine serum albumin–polycaprolactone in lung
cancer. AJR Am. J. Roentgenol. 208(5), 1116–1126 (2017)
290
H.-J. Im and G. J. Cheon