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50. Y. Yu, S. Xu, H. You, Y. Zhang, B. Yang, X. Sun et al., In vivo synergistic anti-tumor effect
of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma. Drug
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51. K. Pant, O. Sedlacek, R.A. Nadar, M. Hruby, H. Stephan, Radiolabeled polymeric materials
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15 Preclinical PET and SPECT for Radionanomedicine
291
animal imaging: basics and practical guide, ed. by F. Kiessling, B.J. Pichler, P. Hauff
(Springer, Cham, 2017), pp. 361–402
35. S. Kalman, Introduction to PET instrumentation. J. Nucl. Med. Technol. 30(2), 63 (2002)
36. A. Rahmim, H. Zaidi, PET versus SPECT: strengths, limitations and challenges. Nucl. Med.
Commun. 29, 193–207 (2008)
37. N. Oku, M. Yamashita, Y. Katayama, T. Urakami, K. Hatanaka, K. Shimizu et al., PET
imaging of brain cancer with positron emitter-labeled liposomes. Int. J. Pharm. 403(1–2),
170–177 (2011)
38. S. Goel, F. Chen, H. Hong, H.F. Valdovinos, R. Hernandez, S. Shi et al., VEGF 121 -
conjugated mesoporous silica nanoparticle: a tumor targeted drug delivery system. ACS Appl.
Mater. Inter. 6(23), 21677–21685 (2014)
39. R. Chakravarty, S. Goel, H. Hong, F. Chen, H.F. Valdovinos, R. Hernandez et al., Hollow
mesoporous silica nanoparticles for tumor vasculature targeting and PET image-guided drug
delivery. Nanomedicine (London) 10(8), 1233–1246 (2015)
40. F. Gao, P. Cai, W. Yang, J. Xue, L. Gao, R. Liu et al., Ultrasmall [
64
Cu]Cu nanoclusters for
targeting orthotopic lung tumors using accurate positron emission tomography imaging. ACS
Nano 9(5), 4976–4986 (2015)
41. H. Hong, F. Wang, Y. Zhang, S.A. Graves, S.B. Eddine, Y. Yang et al., Red fluorescent zinc
oxide nanoparticle: a novel platform for cancer targeting. ACS Appl. Mater. Inter. 7(5), 3373–
3381 (2015)
42. K. Hu, H. Wang, G. Tang, T. Huang, X. Tang, X. Liang et al., In vivo cancer dual-targeting
and dual-modality imaging with functionalized quantum dots. J. Nucl. Med. 56(8), 1278–
1284 (2015)
43. P. Huda, T. Binderup, M.C. Pedersen, S.R. Midtgaard, D.R. Elema, A. Kjaer et al., PET/CT
based in vivo evaluation of
64
Cu labeled nanodiscs in tumor bearing mice. PLoS ONE 10(7),
e0129310 (2015)
44. J. Key, A.L. Palange, F. Gentile, S. Aryal, C. Stigliano, D. Di Mascolo et al., Soft discoidal
polymeric nanoconstructs resist macrophage uptake and enhance vascular targeting in tumors.
ACS Nano 9(12), 11628–11641 (2015)
45. Z. Yang, R. Tian, J. Wu, Q. Fan, B.C. Yung, G. Niu et al., Impact of semiconducting perylene
diimide nanoparticle size on lymph node mapping and cancer imaging. ACS Nano 11(4),
4247–4255 (2017)
46. J. Key, Y.S. Kim, F. Tatulli, A.L. Palange, B. O’Neill, S. Aryal et al., Opportunities for nano
theranosis in lung cancer and pulmonary metastasis. Clin. Transl. Imaging 2(5), 427–437
(2014)
47. D. Chen, C.A. Dougherty, K. Zhu, H. Hong, Theranostic applications of carbon nanomaterials
in cancer: Focus on imaging and cargo delivery. J. Control Release 210, 230–245 (2015)
48. F. Chen, H. Hong, S. Goel, S.A. Graves, H. Orbay, E.B. Ehlerding et al., In vivo tumor
vasculature targeting of CuS@MSN based theranostic nanomedicine. ACS Nano 9(4), 3926–
3934 (2015)
49. L. Cui, Q. Lin, C.S. Jin, W. Jiang, H. Huang, L. Ding et al., A PEGylation-free biomimetic
porphyrin nanoplatform for personalized cancer theranostics. ACS Nano 9(4), 4484–4495
(2015)
50. Y. Yu, S. Xu, H. You, Y. Zhang, B. Yang, X. Sun et al., In vivo synergistic anti-tumor effect
of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma. Drug
Deliv. 24(1), 75–82 (2017)
51. K. Pant, O. Sedlacek, R.A. Nadar, M. Hruby, H. Stephan, Radiolabeled polymeric materials
for imaging and treatment of cancer: Quo vadis? Adv. Healthcare Mater. 6(6) (2017)
52. L. Cheng, A. Kamkaew, H. Sun, D. Jiang, H.F. Valdovinos, H. Gong et al., Dual-modality
positron emission tomography/optical image-guided photodynamic cancer therapy with
chlorin e6-containing nanomicelles. ACS Nano 10(8), 7721–7730 (2016)
15 Preclinical PET and SPECT for Radionanomedicine
291