115
157. Mamchaoui, K., & Saumon, G. (2000). A method for measuring the oxygen consumption
of intact cell monolayers. American Journal of Physiology. Lung Cellular and Molecular
Physiology, 278(4), L858–L863.
158. Mammoto, A., Connor, K. M., Mammoto, T., Yung, C. W., Huh, D., Aderman, C. M., et al.
(2009). A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature,
457(7233), 1103–1108.
159. Manalo, D. J., Rowan, A., Lavoie, T., Natarajan, L., Kelly, B. D., Ye, S. Q., et al. (2005).
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood,
105(2), 659–669.
160. Martorell, L., Gentile, M., Rius, J., Rodriguez, C., Crespo, J., Badimon, L., et al. (2009). The
hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to
hypoxia. Molecular and Cellular Biology, 29(21), 5828–5842.
161. Massabuau, J. C. (2001). From low arterial- to low tissue-oxygenation strategy. An evolutionary theory. Respiration Physiology, 128(3), 249–261.
162. Massabuau, J. C. (2003). Primitive, and protective, our cellular oxygenation status?
Mechanisms of Ageing and Development, 124(8-9), 857–863.
163. Mehta, G., Mehta, K., Sud, D., Song, J. W., Bersano-Begey, T., Futai, N., et al. (2007).
Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane)
bioreactors during cell culture. Biomedical Microdevices, 9(2), 123–134.
164. Melero-Martin, J. M., De Obaldia, M. E., Kang, S. Y., Khan, Z. A., Yuan, L., Oettgen, P., et
al. (2008). Engineering robust and functional vascular networks in vivo with human adult and
cord blood-derived progenitor cells. Circulation Research, 103(2), 194–202.
165. Moon, J. J., Hahn, M. S., Kim, I., Nsiah, B. A., & West, J. L. (2009). Micropatterning of
poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis. Tissue Engineering Part A, 15(3), 579–585.
166. Moon, J. J., Saik, J. E., Poché, R. A., Leslie-Barbick, J. E., Lee, S.-H., Smith, A. A., et
al. (2010). Biomimetic hydrogels with pro-angiogenic properties. Biomaterials, 31(14),
3840–3847.
167. Myllyharju, J., & Schipani, E. (2010). Extracellular matrix genes as hypoxia-inducible targets. Cell and Tissue Research, 339(1), 19–29.
168. Niebruegge, S., Bauwens, C. L., Peerani, R., Thavandiran, N., Masse, S., Sevaptisidis, E.,
et al. (2009). Generation of human embryonic stem cell-derived mesoderm and cardiac
cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnology and
Bioengineering, 102(2), 493–507.
169. Oppegard, S. C., Blake, A. J., Williams, J. C., & Eddington, D. T. (2010). Precise control over
the oxygen conditions within the Boyden chamber using a microfabricated insert. Lab on a
Chip, 10(18), 2366–2373.
170. Ottino, P., Finley, J., Rojo, E., Ottlecz, A., Lambrou, G. N., Bazan, H. E., et al. (2004).
Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity. Molecular
Vision, 10, 341–350.
171. Papandreou, I., Cairns, R. A., Fontana, L., Lim, A. L., & Denko, N. C. (2006). HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
Cell Metabolism, 3(3), 187–197.
172. Papandreou, I., Lim, A. L., Laderoute, K., & Denko, N. C. (2008). Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L. Cell
Death and Differentiation, 15(10), 1572–1581.
173. Park, K. M., & Gerecht, S. (2014). Hypoxia-inducible hydrogels. Nature Communications, 5,
12.
174. Park, T. G., & Hoffman, A. S. (1992). Synthesis and characterization of pH- and or temperature-sensitive hydrogels. Journal of Applied Polymer Science, 46(4), 659–671.
175. Parmar, K., Mauch, P., Vergilio, J. A., Sackstein, R., & Down, J. D. (2007). Distribution of
hematopoietic stem cells in the bone marrow according to regional hypoxia. Proceedings of
the National Academy of Sciences of the United States of America, 104(13), 5431–5436.
4 Hypoxia and Matrix Manipulation for Vascular Engineering
157. Mamchaoui, K., & Saumon, G. (2000). A method for measuring the oxygen consumption
of intact cell monolayers. American Journal of Physiology. Lung Cellular and Molecular
Physiology, 278(4), L858–L863.
158. Mammoto, A., Connor, K. M., Mammoto, T., Yung, C. W., Huh, D., Aderman, C. M., et al.
(2009). A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature,
457(7233), 1103–1108.
159. Manalo, D. J., Rowan, A., Lavoie, T., Natarajan, L., Kelly, B. D., Ye, S. Q., et al. (2005).
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood,
105(2), 659–669.
160. Martorell, L., Gentile, M., Rius, J., Rodriguez, C., Crespo, J., Badimon, L., et al. (2009). The
hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to
hypoxia. Molecular and Cellular Biology, 29(21), 5828–5842.
161. Massabuau, J. C. (2001). From low arterial- to low tissue-oxygenation strategy. An evolutionary theory. Respiration Physiology, 128(3), 249–261.
162. Massabuau, J. C. (2003). Primitive, and protective, our cellular oxygenation status?
Mechanisms of Ageing and Development, 124(8-9), 857–863.
163. Mehta, G., Mehta, K., Sud, D., Song, J. W., Bersano-Begey, T., Futai, N., et al. (2007).
Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane)
bioreactors during cell culture. Biomedical Microdevices, 9(2), 123–134.
164. Melero-Martin, J. M., De Obaldia, M. E., Kang, S. Y., Khan, Z. A., Yuan, L., Oettgen, P., et
al. (2008). Engineering robust and functional vascular networks in vivo with human adult and
cord blood-derived progenitor cells. Circulation Research, 103(2), 194–202.
165. Moon, J. J., Hahn, M. S., Kim, I., Nsiah, B. A., & West, J. L. (2009). Micropatterning of
poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis. Tissue Engineering Part A, 15(3), 579–585.
166. Moon, J. J., Saik, J. E., Poché, R. A., Leslie-Barbick, J. E., Lee, S.-H., Smith, A. A., et
al. (2010). Biomimetic hydrogels with pro-angiogenic properties. Biomaterials, 31(14),
3840–3847.
167. Myllyharju, J., & Schipani, E. (2010). Extracellular matrix genes as hypoxia-inducible targets. Cell and Tissue Research, 339(1), 19–29.
168. Niebruegge, S., Bauwens, C. L., Peerani, R., Thavandiran, N., Masse, S., Sevaptisidis, E.,
et al. (2009). Generation of human embryonic stem cell-derived mesoderm and cardiac
cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnology and
Bioengineering, 102(2), 493–507.
169. Oppegard, S. C., Blake, A. J., Williams, J. C., & Eddington, D. T. (2010). Precise control over
the oxygen conditions within the Boyden chamber using a microfabricated insert. Lab on a
Chip, 10(18), 2366–2373.
170. Ottino, P., Finley, J., Rojo, E., Ottlecz, A., Lambrou, G. N., Bazan, H. E., et al. (2004).
Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity. Molecular
Vision, 10, 341–350.
171. Papandreou, I., Cairns, R. A., Fontana, L., Lim, A. L., & Denko, N. C. (2006). HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
Cell Metabolism, 3(3), 187–197.
172. Papandreou, I., Lim, A. L., Laderoute, K., & Denko, N. C. (2008). Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L. Cell
Death and Differentiation, 15(10), 1572–1581.
173. Park, K. M., & Gerecht, S. (2014). Hypoxia-inducible hydrogels. Nature Communications, 5,
12.
174. Park, T. G., & Hoffman, A. S. (1992). Synthesis and characterization of pH- and or temperature-sensitive hydrogels. Journal of Applied Polymer Science, 46(4), 659–671.
175. Parmar, K., Mauch, P., Vergilio, J. A., Sackstein, R., & Down, J. D. (2007). Distribution of
hematopoietic stem cells in the bone marrow according to regional hypoxia. Proceedings of
the National Academy of Sciences of the United States of America, 104(13), 5431–5436.
4 Hypoxia and Matrix Manipulation for Vascular Engineering