116
176. Phelps, E. A., Landazuri, N., Thule, P. M., Taylor, W. R., & Garcia, A. J. (2009). Bioartificial
matrices for therapeutic vascularization. Proceedings of the National Academy of Sciences,
107(8), 3323–3328.
177. Phillips, P. G., Birnby, L. M., & Narendran, A. (1995). Hypoxia induces capillary network
formation in cultured bovine pulmonary microvessel endothelial cells. The American Journal
of Physiology, 268(5 Pt 1), L789–L800.
178. Pierschbacher, M. D., & Ruoslahti, E. (1984). Cell attachment activity of fibronectin can be
duplicated by small synthetic fragments of the molecule. Nature, 309(5963), 30–33.
179. Pollard, P. J., Loenarz, C., Mole, D. R., McDonough, M. A., Gleadle, J. M., Schofield, C. J.,
et al. (2008). Regulation of Jumonji-domain-containing histone demethylases by hypoxiainducible factor (HIF)-1alpha. The Biochemical Journal, 416(3), 387–394.
180. Popel, A. S. (1989). Theory of oxygen transport to tissue. Critical Reviews in Biomedical
Engineering, 17(3), 257–321.
181. Prado-Lopez, S., Conesa, A., Arminan, A., Martinez-Losa, M., Escobedo-Lucea, C., Gandia,
C., et al. (2010). Hypoxia promotes efficient differentiation of human embryonic stem cells
to functional endothelium. Stem Cells, 28, 407–418.
182. Prasad, S. M., Czepiel, M., Cetinkaya, C., Smigielska, K., Weli, S. C., Lysdahl, H., et al.
(2009). Continuous hypoxic culturing maintains activation of Notch and allows long-term
propagation of human embryonic stem cells without spontaneous differentiation. Cell
Proliferation, 42(1), 63–74.
183. Radisic, M., Deen, W., Langer, R., & Vunjak-Novakovic, G. (2005). Mathematical model of
oxygen distribution in engineered cardiac tissue with parallel channel array perfused with
culture medium containing oxygen carriers. American Journal of Physiology. Heart and
Circulatory Physiology, 288(3), H1278–H1289.
184. Risau, W. (1997). Mechanisms of angiogenesis. Nature, 386(6626), 671–674.
185. Risau, W., & Flamme, I. (1995). Vasculogenesis. Annual Review of Cell and Developmental
Biology, 11, 73–91.
186. Robins, S. P. (2007). Biochemistry and functional significance of collagen cross-linking.
Biochemical Society Transactions, 35(5), 849–852.
187. Rodenhizer, D., Gaude, E., Cojocari, D., Mahadevan, R., Frezza, C., Wouters, B. G., et al.
(2016). A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients. Nature Materials, 15(2), 227.
188. Rodesch, F., Simon, P., Donner, C., & Jauniaux, E. (1992). Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstetrics and Gynecology, 80(2),
283–285.
189. Roeder, B. A., Kokini, K., Sturgis, J. E., Robinson, J. P., & Voytik-Harbin, S. L. (2002).
Tensile mechanical properties of three-dimensional type I collagen extracellular matrices
with varied microstructure. Journal of Biomechanical Engineering, 124(2), 214–222.
190. Romer, L. H., Birukov, K. G., & Garcia, J. G. (2006). Focal adhesions: Paradigm for a signaling nexus. Circulation Research, 98(5), 606–616.
191. Rosenfeld, D., Landau, S., Shandalov, Y., Raindel, N., Freiman, A., Shor, E., et al. (2016).
Morphogenesis of 3D vascular networks is regulated by tensile forces. Proceedings of the
National Academy of Sciences of the United States of America, 113(12), 3215–3220.
192. Sage, E. H., & Vernon, R. B. (1994). Regulation of angiogenesis by extracellular matrix: The
growth and the glue. Journal of Hypertension, 12(suppl. 10), S145–S152.
193. Saunders, W. B., Bayless, K. J., & Davis, G. E. (2005). MMP-1 activation by serine proteases
and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. Journal of Cell Science, 118(Pt 10), 2325–2340.
194. Scott, C., Lyons, T. W., Bekker, A., Shen, Y., Poulton, S. W., Chu, X., et al. (2008). Tracing
the stepwise oxygenation of the Proterozoic ocean. Nature, 452(7186), 456–459.
195. Segura, I., Serrano, A., De Buitrago, G. G., Gonzalez, M. A., Abad, J. L., Claveria, C., et al.
(2002). Inhibition of programmed cell death impairs in vitro vascular-like structure formation
and reduces in vivo angiogenesis. The FASEB Journal, 16(8), 833–841.
M. R. Blatchley et al.
176. Phelps, E. A., Landazuri, N., Thule, P. M., Taylor, W. R., & Garcia, A. J. (2009). Bioartificial
matrices for therapeutic vascularization. Proceedings of the National Academy of Sciences,
107(8), 3323–3328.
177. Phillips, P. G., Birnby, L. M., & Narendran, A. (1995). Hypoxia induces capillary network
formation in cultured bovine pulmonary microvessel endothelial cells. The American Journal
of Physiology, 268(5 Pt 1), L789–L800.
178. Pierschbacher, M. D., & Ruoslahti, E. (1984). Cell attachment activity of fibronectin can be
duplicated by small synthetic fragments of the molecule. Nature, 309(5963), 30–33.
179. Pollard, P. J., Loenarz, C., Mole, D. R., McDonough, M. A., Gleadle, J. M., Schofield, C. J.,
et al. (2008). Regulation of Jumonji-domain-containing histone demethylases by hypoxiainducible factor (HIF)-1alpha. The Biochemical Journal, 416(3), 387–394.
180. Popel, A. S. (1989). Theory of oxygen transport to tissue. Critical Reviews in Biomedical
Engineering, 17(3), 257–321.
181. Prado-Lopez, S., Conesa, A., Arminan, A., Martinez-Losa, M., Escobedo-Lucea, C., Gandia,
C., et al. (2010). Hypoxia promotes efficient differentiation of human embryonic stem cells
to functional endothelium. Stem Cells, 28, 407–418.
182. Prasad, S. M., Czepiel, M., Cetinkaya, C., Smigielska, K., Weli, S. C., Lysdahl, H., et al.
(2009). Continuous hypoxic culturing maintains activation of Notch and allows long-term
propagation of human embryonic stem cells without spontaneous differentiation. Cell
Proliferation, 42(1), 63–74.
183. Radisic, M., Deen, W., Langer, R., & Vunjak-Novakovic, G. (2005). Mathematical model of
oxygen distribution in engineered cardiac tissue with parallel channel array perfused with
culture medium containing oxygen carriers. American Journal of Physiology. Heart and
Circulatory Physiology, 288(3), H1278–H1289.
184. Risau, W. (1997). Mechanisms of angiogenesis. Nature, 386(6626), 671–674.
185. Risau, W., & Flamme, I. (1995). Vasculogenesis. Annual Review of Cell and Developmental
Biology, 11, 73–91.
186. Robins, S. P. (2007). Biochemistry and functional significance of collagen cross-linking.
Biochemical Society Transactions, 35(5), 849–852.
187. Rodenhizer, D., Gaude, E., Cojocari, D., Mahadevan, R., Frezza, C., Wouters, B. G., et al.
(2016). A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients. Nature Materials, 15(2), 227.
188. Rodesch, F., Simon, P., Donner, C., & Jauniaux, E. (1992). Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstetrics and Gynecology, 80(2),
283–285.
189. Roeder, B. A., Kokini, K., Sturgis, J. E., Robinson, J. P., & Voytik-Harbin, S. L. (2002).
Tensile mechanical properties of three-dimensional type I collagen extracellular matrices
with varied microstructure. Journal of Biomechanical Engineering, 124(2), 214–222.
190. Romer, L. H., Birukov, K. G., & Garcia, J. G. (2006). Focal adhesions: Paradigm for a signaling nexus. Circulation Research, 98(5), 606–616.
191. Rosenfeld, D., Landau, S., Shandalov, Y., Raindel, N., Freiman, A., Shor, E., et al. (2016).
Morphogenesis of 3D vascular networks is regulated by tensile forces. Proceedings of the
National Academy of Sciences of the United States of America, 113(12), 3215–3220.
192. Sage, E. H., & Vernon, R. B. (1994). Regulation of angiogenesis by extracellular matrix: The
growth and the glue. Journal of Hypertension, 12(suppl. 10), S145–S152.
193. Saunders, W. B., Bayless, K. J., & Davis, G. E. (2005). MMP-1 activation by serine proteases
and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. Journal of Cell Science, 118(Pt 10), 2325–2340.
194. Scott, C., Lyons, T. W., Bekker, A., Shen, Y., Poulton, S. W., Chu, X., et al. (2008). Tracing
the stepwise oxygenation of the Proterozoic ocean. Nature, 452(7186), 456–459.
195. Segura, I., Serrano, A., De Buitrago, G. G., Gonzalez, M. A., Abad, J. L., Claveria, C., et al.
(2002). Inhibition of programmed cell death impairs in vitro vascular-like structure formation
and reduces in vivo angiogenesis. The FASEB Journal, 16(8), 833–841.
M. R. Blatchley et al.