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Springer US (2011). doi:10.1007/978-1-4419-9583-4
19. M.A. Aronova, R.D. Leapman, Development of electron energy-loss spectroscopy in the
biological sciences. MRS Bull. 37(1), 53–62 (2012). doi:10.1557/mrs.2011.329
20. S.G. Wolf, L. Houben, M. Elbaum, Cryo-scanning transmission electron tomography of
vitrified cells. Nat. Methods 11(4), 423–428 (2014). doi:10.1038/nmeth.2842
21. L. Reimer, H. Kohl, Transmission electron microscopy: physics of image formation (2008).
doi:10.1007/978-0-387-40093-8
22. L. Reimer, M. Ross-Messemer, Contrast in the electron spectroscopic imaging mode of a
TEM. J. Microsc. 159(2), 143–160 (1990). doi:10.1111/j.1365-2818.1990.tb04772.x
23. S. Sun, S. Shi, R. Leapman, Water distributions of hydrated biological specimens by valence
electron energy loss spectroscopy. Ultramicroscopy 50(2), 127–139 (1993). doi:http://dx.
doi.org/10.1016/0304-3991(93)90003-G
24. P. Rez, Comparison of phase contrast transmission electron microscopy with optimized
scanning transmission annular dark field imaging for protein imaging. Ultramicroscopy 96
(1), 117–124 (2003). doi:10.1016/S0304-3991(02)00436-9
25. J.S. Wall, J.F. Hainfeld, M.N. Simon, Scanning transmission electron microscopy of nuclear
structures. Methods Cell Biol. 53, 139–164 (1998)
26. H. Rose, Influence of plural scattering on the image quality of thick amorphous objects in
transmission electron microscopy. in 9th International Congress on Electron Microscopy,
Toronto, 1978. pp 230–243
27. J.K. Hyun, P. Ercius, D.A. Muller, Beam spreading and spatial resolution in thick organic
specimens. Ultramicroscopy 109(1), 1–7 (2008). doi:10.1016/j.ultramic.2008.07.003
28. A.A. Sousa, M.F. Hohmann-Marriott, G. Zhang, R.D. Leapman, Monte Carlo
electron-trajectory simulations in bright-field and dark-field STEM: implications for
tomography of thick biological sections. Ultramicroscopy 109(3), 213–221 (2009)
29. J. Barthel, Time-efficient frozen phonon multislice calculations for image simulations in
high-resolution STEM, in Proceedings of the 15th European Microscopy Congress,
Manchester, 2012
30. R. Reichelt, A. Engel, Contrast and resolution of scanning transmission electron microscope
imaging modes. Ultramicroscopy 19(1), 43–56 (1986)
31. M.F. Hohmann-Marriott, A.A. Sousa, A.A. Azari, S. Glushakova, G. Zhang, J. Zimmerberg,
R.D. Leapman, Nanoscale 3D cellular imaging by axial scanning transmission electron
tomography. Nat. Methods 6(10), 729–731 (2009). doi:10.1038/nmeth.1367
32. K. Aoyama, T. Takagi, A. Hirase, A. Miyazawa, STEM tomography for thick biological
specimens. Ultramicroscopy 109, 70–80 (2008). doi:10.1016/j.ultramic.2008.08.005
33. H. Hashimoto, in Proceedings. AMU-ANL Workshop on High Voltage Electron Microscopy,
Argonne National Laboratory, 1966, pp. 68–70
34. L. Reimer, P. Gentsch, Superposition of chromatic error and beam broadening in
transmission electron microscopy of thick carbon and organic specimens. Ultramicroscopy
1(1), 1–5 (1975)
35. S. Trepout, C. Messaoudi, S. Perrot, P. Bastin, S. Marco, Scanning transmission electron
microscopy through-focal tilt-series on biological specimens. Micron (Oxford, England:
1993) 77, 9–15 (2015). doi:http://dx.doi.org/10.1016/j.micron.2015.05.015
36. T. Dahmen, H. Kohr, N. de Jonge, P. Slusallek, Matched backprojection operator for
combined scanning transmission electron microscopy tilt- and focal series. Microsc.
Microanal. 21(03), 725–738 (2015)
37. P. Rez, T. Larsen, M. Elbaum, Exploring the theoretical basis and limitations of cryo-STEM
tomography for thick biological specimens. J. Struct. Biol. 196(3), 466–478 (2016)
38. J.S. Wu, A.M. Kim, R. Bleher, B.D. Myers, R.G. Marvin, H. Inada, K. Nakamura, X.F.
Zhang, E. Roth, S.Y. Li, T.K. Woodruff, T.V. O’Halloran, V.P. Dravid, Imaging and
56
S. G. Wolf et al.
10.1016/B978-0-12-394297-5.00006-4
18. R. Egerton, Electron energy-loss spectroscopy in the electron microscope. 3 edn.
Springer US (2011). doi:10.1007/978-1-4419-9583-4
19. M.A. Aronova, R.D. Leapman, Development of electron energy-loss spectroscopy in the
biological sciences. MRS Bull. 37(1), 53–62 (2012). doi:10.1557/mrs.2011.329
20. S.G. Wolf, L. Houben, M. Elbaum, Cryo-scanning transmission electron tomography of
vitrified cells. Nat. Methods 11(4), 423–428 (2014). doi:10.1038/nmeth.2842
21. L. Reimer, H. Kohl, Transmission electron microscopy: physics of image formation (2008).
doi:10.1007/978-0-387-40093-8
22. L. Reimer, M. Ross-Messemer, Contrast in the electron spectroscopic imaging mode of a
TEM. J. Microsc. 159(2), 143–160 (1990). doi:10.1111/j.1365-2818.1990.tb04772.x
23. S. Sun, S. Shi, R. Leapman, Water distributions of hydrated biological specimens by valence
electron energy loss spectroscopy. Ultramicroscopy 50(2), 127–139 (1993). doi:http://dx.
doi.org/10.1016/0304-3991(93)90003-G
24. P. Rez, Comparison of phase contrast transmission electron microscopy with optimized
scanning transmission annular dark field imaging for protein imaging. Ultramicroscopy 96
(1), 117–124 (2003). doi:10.1016/S0304-3991(02)00436-9
25. J.S. Wall, J.F. Hainfeld, M.N. Simon, Scanning transmission electron microscopy of nuclear
structures. Methods Cell Biol. 53, 139–164 (1998)
26. H. Rose, Influence of plural scattering on the image quality of thick amorphous objects in
transmission electron microscopy. in 9th International Congress on Electron Microscopy,
Toronto, 1978. pp 230–243
27. J.K. Hyun, P. Ercius, D.A. Muller, Beam spreading and spatial resolution in thick organic
specimens. Ultramicroscopy 109(1), 1–7 (2008). doi:10.1016/j.ultramic.2008.07.003
28. A.A. Sousa, M.F. Hohmann-Marriott, G. Zhang, R.D. Leapman, Monte Carlo
electron-trajectory simulations in bright-field and dark-field STEM: implications for
tomography of thick biological sections. Ultramicroscopy 109(3), 213–221 (2009)
29. J. Barthel, Time-efficient frozen phonon multislice calculations for image simulations in
high-resolution STEM, in Proceedings of the 15th European Microscopy Congress,
Manchester, 2012
30. R. Reichelt, A. Engel, Contrast and resolution of scanning transmission electron microscope
imaging modes. Ultramicroscopy 19(1), 43–56 (1986)
31. M.F. Hohmann-Marriott, A.A. Sousa, A.A. Azari, S. Glushakova, G. Zhang, J. Zimmerberg,
R.D. Leapman, Nanoscale 3D cellular imaging by axial scanning transmission electron
tomography. Nat. Methods 6(10), 729–731 (2009). doi:10.1038/nmeth.1367
32. K. Aoyama, T. Takagi, A. Hirase, A. Miyazawa, STEM tomography for thick biological
specimens. Ultramicroscopy 109, 70–80 (2008). doi:10.1016/j.ultramic.2008.08.005
33. H. Hashimoto, in Proceedings. AMU-ANL Workshop on High Voltage Electron Microscopy,
Argonne National Laboratory, 1966, pp. 68–70
34. L. Reimer, P. Gentsch, Superposition of chromatic error and beam broadening in
transmission electron microscopy of thick carbon and organic specimens. Ultramicroscopy
1(1), 1–5 (1975)
35. S. Trepout, C. Messaoudi, S. Perrot, P. Bastin, S. Marco, Scanning transmission electron
microscopy through-focal tilt-series on biological specimens. Micron (Oxford, England:
1993) 77, 9–15 (2015). doi:http://dx.doi.org/10.1016/j.micron.2015.05.015
36. T. Dahmen, H. Kohr, N. de Jonge, P. Slusallek, Matched backprojection operator for
combined scanning transmission electron microscopy tilt- and focal series. Microsc.
Microanal. 21(03), 725–738 (2015)
37. P. Rez, T. Larsen, M. Elbaum, Exploring the theoretical basis and limitations of cryo-STEM
tomography for thick biological specimens. J. Struct. Biol. 196(3), 466–478 (2016)
38. J.S. Wu, A.M. Kim, R. Bleher, B.D. Myers, R.G. Marvin, H. Inada, K. Nakamura, X.F.
Zhang, E. Roth, S.Y. Li, T.K. Woodruff, T.V. O’Halloran, V.P. Dravid, Imaging and
56
S. G. Wolf et al.