14. Peng Y, Zhang D, Li Y, Qi H, Gao Q, Zhang C (2009) Label-free and sensitive faradic
impedance aptasensor for the determination of lysozyme based on target-induced aptamer
displacement. Biosens Bioelectron 25(1):94–99. https://doi.org/10.1016/j.bios.2009.06.001
15. Xia Y, Gan S, Xu Q, Qiu X, Gao P, Huang S (2013) A three-way junction aptasensor for
lysozyme detection. Biosens Bioelectron 39(1):250–254. https://doi.org/10.1016/j.bios.2012.
07.053
16. Zhang Z, Zhang S, He L, Peng D, Yan F, Wang M, Zhao J, Zhang H, Fang S (2015) Feasible
electrochemical biosensor based on plasma polymerization-assisted composite of polyacrylic
acid and hollow TiO 2 spheres for sensitively detecting lysozyme. Biosens Bioelectron
74:384–390. https://doi.org/10.1016/j.bios.2015.06.062
17. Chen ZB, Li LD, Zhao HT, Guo L, Mu XJ (2011) Electrochemical impedance spectroscopy
detection of lysozyme based on electrodeposited gold nanoparticles. Talanta 83
(5):1501–1506. https://doi.org/10.1016/j.talanta.2010.11.042
18. Khan NI, Maddaus AG, Song E (2018) A low-cost inkjet-printed aptamer-based electrochemical biosensor for the selective detection of lysozyme. Biosensors 8(1):7. https://doi.org/10.
3390/bios8010007
19. Dong YP, Wang J, Peng Y, Zhu JJ (2017) A novel aptasensor for lysozyme based on
electrogenerated chemiluminescence resonance energy transfer between luminol and silicon
quantum dots. Biosens Bioelectron 94:530–535. https://doi.org/10.1016/j.bios.2017.03.044
20. Krenzlin H, Lorenz V, Danckwardt S, Kempski O, Alessandri B (2016) The importance of
thrombin in cerebral injury and disease. Int J Mol Sci 17(1):84. https://doi.org/10.3390/
ijms17010084
21. Deng CY, Chen JH, Nie LH, Nie Z, Yao SZ (2009) Sensitive bifunctional aptamer-based
electrochemical biosensor for small molecules and protein. Anal Chem 81(24):9972–9978.
https://doi.org/10.1021/ac901727z
22. Lu L, Li J, Kang T, Cheng S (2015) Bi-functionalized aptasensor for ultrasensitive detection of
thrombin. Talanta 138:273–278. https://doi.org/10.1016/j.talanta.2015.03.016
23. Heydari-Bafrooei E, Amini M, Ardakani MH (2016) An electrochemical aptasensor based on
TiO 2 /MWCNT and a novel synthesized Schiff base nanocomposite for the ultrasensitive
detection of thrombin. Biosens Bioelectron 85:828–836. https://doi.org/10.1016/j.bios.2016.
06.012
24. Gaffen SL (2009) Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 9
(8):556–567. https://doi.org/10.1038/nri2586
25. Tertiş M, Ciui B, Suciu M, Săndulescu R, Cristea C (2017) Label-free electrochemical
aptasensor based on gold and polypyrrole nanoparticles for interleukin 6 detection.
Electrochim Acta 258:1208–1218. https://doi.org/10.1016/j.electacta.2017.11.176
26. Jo H, Gu H, Jeon W, Youn H, Her J, Kim SK, Lee J, Shin JH, Ban C (2015) Electrochemical
Aptasensor of cardiac troponin I for the early diagnosis of acute myocardial infarction. Anal
Chem 87(19):9869–9875. https://doi.org/10.1021/acs.analchem.5b02312
27. Boriani G, Biffi M, Cervi V, Bronzetti G, Magagnoli G, Zannoli R, Branzi A (2000)
Evaluation of myocardial injury following repeated internal atrial shocks by monitoring
serum cardiac troponin I levels. Chest 118(2):342–347. https://doi.org/10.1378/chest.118.2.
342
28. Wang B, Jing R, Qi HL, Gao Q, Zhang CX (2016) Label-free electrochemical impedance
peptide-based biosensor for the detection of cardiac troponin I incorporating gold
nanoparticles modified carbon electrode. J Electroanal Chem 781:212–217. https://doi.org/
10.1016/j.jelechem.2016.08.005
29. Akter R, Jeong B, Lee YM, Choi JS, Rahman MA (2017) Femtomolar detection of cardiac
troponin I using a novel label-free and reagent-free dendrimer enhanced impedimetric
immunosensor. Biosens Bioelectron 91:637–643. https://doi.org/10.1016/j.bios.2017.01.021
30. Jorgensen P, Chanthap L, Rebueno A, Tsuyuoka R, Bell D (2006) Malaria rapid diagnostic
tests in tropical climates: the need for a cool chain. Am J Trop Med Hyg 74(5):750–754.
https://doi.org/10.4269/ajtmh.2006.74.750
82
J.-A. Preuß et al.
impedance aptasensor for the determination of lysozyme based on target-induced aptamer
displacement. Biosens Bioelectron 25(1):94–99. https://doi.org/10.1016/j.bios.2009.06.001
15. Xia Y, Gan S, Xu Q, Qiu X, Gao P, Huang S (2013) A three-way junction aptasensor for
lysozyme detection. Biosens Bioelectron 39(1):250–254. https://doi.org/10.1016/j.bios.2012.
07.053
16. Zhang Z, Zhang S, He L, Peng D, Yan F, Wang M, Zhao J, Zhang H, Fang S (2015) Feasible
electrochemical biosensor based on plasma polymerization-assisted composite of polyacrylic
acid and hollow TiO 2 spheres for sensitively detecting lysozyme. Biosens Bioelectron
74:384–390. https://doi.org/10.1016/j.bios.2015.06.062
17. Chen ZB, Li LD, Zhao HT, Guo L, Mu XJ (2011) Electrochemical impedance spectroscopy
detection of lysozyme based on electrodeposited gold nanoparticles. Talanta 83
(5):1501–1506. https://doi.org/10.1016/j.talanta.2010.11.042
18. Khan NI, Maddaus AG, Song E (2018) A low-cost inkjet-printed aptamer-based electrochemical biosensor for the selective detection of lysozyme. Biosensors 8(1):7. https://doi.org/10.
3390/bios8010007
19. Dong YP, Wang J, Peng Y, Zhu JJ (2017) A novel aptasensor for lysozyme based on
electrogenerated chemiluminescence resonance energy transfer between luminol and silicon
quantum dots. Biosens Bioelectron 94:530–535. https://doi.org/10.1016/j.bios.2017.03.044
20. Krenzlin H, Lorenz V, Danckwardt S, Kempski O, Alessandri B (2016) The importance of
thrombin in cerebral injury and disease. Int J Mol Sci 17(1):84. https://doi.org/10.3390/
ijms17010084
21. Deng CY, Chen JH, Nie LH, Nie Z, Yao SZ (2009) Sensitive bifunctional aptamer-based
electrochemical biosensor for small molecules and protein. Anal Chem 81(24):9972–9978.
https://doi.org/10.1021/ac901727z
22. Lu L, Li J, Kang T, Cheng S (2015) Bi-functionalized aptasensor for ultrasensitive detection of
thrombin. Talanta 138:273–278. https://doi.org/10.1016/j.talanta.2015.03.016
23. Heydari-Bafrooei E, Amini M, Ardakani MH (2016) An electrochemical aptasensor based on
TiO 2 /MWCNT and a novel synthesized Schiff base nanocomposite for the ultrasensitive
detection of thrombin. Biosens Bioelectron 85:828–836. https://doi.org/10.1016/j.bios.2016.
06.012
24. Gaffen SL (2009) Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 9
(8):556–567. https://doi.org/10.1038/nri2586
25. Tertiş M, Ciui B, Suciu M, Săndulescu R, Cristea C (2017) Label-free electrochemical
aptasensor based on gold and polypyrrole nanoparticles for interleukin 6 detection.
Electrochim Acta 258:1208–1218. https://doi.org/10.1016/j.electacta.2017.11.176
26. Jo H, Gu H, Jeon W, Youn H, Her J, Kim SK, Lee J, Shin JH, Ban C (2015) Electrochemical
Aptasensor of cardiac troponin I for the early diagnosis of acute myocardial infarction. Anal
Chem 87(19):9869–9875. https://doi.org/10.1021/acs.analchem.5b02312
27. Boriani G, Biffi M, Cervi V, Bronzetti G, Magagnoli G, Zannoli R, Branzi A (2000)
Evaluation of myocardial injury following repeated internal atrial shocks by monitoring
serum cardiac troponin I levels. Chest 118(2):342–347. https://doi.org/10.1378/chest.118.2.
342
28. Wang B, Jing R, Qi HL, Gao Q, Zhang CX (2016) Label-free electrochemical impedance
peptide-based biosensor for the detection of cardiac troponin I incorporating gold
nanoparticles modified carbon electrode. J Electroanal Chem 781:212–217. https://doi.org/
10.1016/j.jelechem.2016.08.005
29. Akter R, Jeong B, Lee YM, Choi JS, Rahman MA (2017) Femtomolar detection of cardiac
troponin I using a novel label-free and reagent-free dendrimer enhanced impedimetric
immunosensor. Biosens Bioelectron 91:637–643. https://doi.org/10.1016/j.bios.2017.01.021
30. Jorgensen P, Chanthap L, Rebueno A, Tsuyuoka R, Bell D (2006) Malaria rapid diagnostic
tests in tropical climates: the need for a cool chain. Am J Trop Med Hyg 74(5):750–754.
https://doi.org/10.4269/ajtmh.2006.74.750
82
J.-A. Preuß et al.