216
L. S. Emery and J. M. Akey
Table 9.1
(continued)
Study
Data
Statistic
Population(s)
# Candidates found Candidate regions of note
Hancock et al.
(2010a, b)
0.64M SNPs
Correlation of SNP
frequency with
environmental variable
61 pops: HGDP; Luhya,
Maasai, Tuscan, Gujarati
from HapMap III; !Kung,
Amhara, Yup’ik,
Chukchee, and Aborigine
?
MTRR
PLRP2
KCNQ1
ME3
International HapMap
Consortium (2005)
1 M SNPs
LD (rEHH), population
differentiation
(heterozygosity, low
MAF, p
excess )
3 HapMap I
926 SNPs
14 strong
candidate regions
ALMS1
LCT
International HapMap
Consortium (2007)
3.1 M SNPs
LD (LRH and iHS)
3 HapMap II
200 regions
HBB
LCT
HLA
EDAR
TRPV5
TRPV6
PCDH15
International HapMap
3 Consortium (2010)
3.1 M SNPs
CMS based on FST,
xp-EHH, delta-iHH,
delta-DAF, and iHS
3 non-admixed HapMap
III
(TSI, LWH, MKK)
54 regions
KITLG
MLPH
ANKH
DPP7
Johansson and
Gyllensten (2008)
1.6 M SNPs
Joint analysis of
population differentiation
and LD
(haplotype block length
and FST)
Perlegen
(Eur. Amer., Afr. Amer.,
Han Chinese)
23 regions
EDAR
LCT
Kelley et al. (2006)
1.6 M SNPs assigned
to 14,589 gene
regions
Site frequency spectrum
(Tajima’s D)
Perlegen
385 genes
TRPV6