Review Question 3
Indicate if each of the following descriptions matches RNA (R) or DNA (D). Your
answer would be a five-letter string composed of letters R and D only.
• It is mainly found as a long, double-stranded molecule.
• It contains the sugar ribose.
• It normally contains the bases thymine, cytosine, adenine, and guanine.
• It can normally adopt distinctive folded shapes.
• It can be used as the template for protein synthesis.
Review Question 4
Imagine a segment of DNA (within a gene) encoding a certain amount of information
in its nucleotide sequence. When this segment is fully transcribed into mRNA and then
translated into protein, in general, . . .
A. the protein sequence would carry more information compared to the DNA and
mRNA sequences, because its alphabet has 20 letters.
B. the protein sequence would carry less information compared to the DNA and mRNA
sequences, because several codons can correspond to one amino acid.
C. the amount of information in the mRNA sequence is lower, because the mRNA has
been transcribed using only one of the DNA strands as the template.
D. the amount of information in the mRNA sequence is higher, because several mRNA
molecules can be transcribed from one DNA molecule.
Answers to Review Questions
Answers to Question 1
a) What is the mRNA sequence?
5’-AUGUGGAACCGCUGCUGA-3’
5’-AUGCUGGAACCGCUGCUGA-3’
b) What will be the amino acid sequence?
NH 3
+ - Met- Trp- Asn- Arg- Cys- Stop
NH 3
+ - Met- Leu- Glu- Pro- Leu- Leu- COO
-
c) Will there likely be effects?
Yes
1 Next Generation Sequencing (NGS): What Can Be Sequenced?
13
Indicate if each of the following descriptions matches RNA (R) or DNA (D). Your
answer would be a five-letter string composed of letters R and D only.
• It is mainly found as a long, double-stranded molecule.
• It contains the sugar ribose.
• It normally contains the bases thymine, cytosine, adenine, and guanine.
• It can normally adopt distinctive folded shapes.
• It can be used as the template for protein synthesis.
Review Question 4
Imagine a segment of DNA (within a gene) encoding a certain amount of information
in its nucleotide sequence. When this segment is fully transcribed into mRNA and then
translated into protein, in general, . . .
A. the protein sequence would carry more information compared to the DNA and
mRNA sequences, because its alphabet has 20 letters.
B. the protein sequence would carry less information compared to the DNA and mRNA
sequences, because several codons can correspond to one amino acid.
C. the amount of information in the mRNA sequence is lower, because the mRNA has
been transcribed using only one of the DNA strands as the template.
D. the amount of information in the mRNA sequence is higher, because several mRNA
molecules can be transcribed from one DNA molecule.
Answers to Review Questions
Answers to Question 1
a) What is the mRNA sequence?
5’-AUGUGGAACCGCUGCUGA-3’
5’-AUGCUGGAACCGCUGCUGA-3’
b) What will be the amino acid sequence?
NH 3
+ - Met- Trp- Asn- Arg- Cys- Stop
NH 3
+ - Met- Leu- Glu- Pro- Leu- Leu- COO
-
c) Will there likely be effects?
Yes
1 Next Generation Sequencing (NGS): What Can Be Sequenced?
13
