191
Table 8.1 (continued)
Inhibitors
Target
Category
Species
Reference
Kojic acid
LuxR
Fungi
Aspergillus spp.
Dobretsov
et al. (2011)
Patulin and
Penilillic acid
LasR and RhlR
Fungi
Penicillium spp.
Rasmussen
et al. (2005)
Farnesol
(sesquiterpene)
PqsA
Fungi
Candida albicans Cugini et al.
(2007)
Honey and propolis C. violaceum, LasR,
and RhlR
Insect
productions
Bee
Truchado
et al. (2009)
and Bulman
et al. (2011)
Solenopsin A
Rhl circuit
Insect: Fire
ant
Solenopisinvicta
Park et al.
(2008)
Furanone and its
derivatives
LuxR and LuxS
Marine alga
Delisea pulchra
de Nys et al.
(1993) and
Rice et al.
(2002)
Cyclodepsipeptides
(solonomide a, b)
Agr system
Marine
bacteria
Photobacterium
Mansson
et al. (2011)
Benzopyran
CviR, LuxR and LasR Plant
Baccharis
cassinaefolia
Dobretsov
et al. (2011)
Eugenol
CviR, LasR and PQS Plant
Syzygium
aromaticum
Zhou et al.
(2013)
Cinnamaldehyde
and its derivatives
LuxR and AI-2
Plant
Many plants
Niu et al.
(2006),
Brackman
et al. (2008)
and
Brackman
et al.
(2011a)
Quercetin
AI-2 and AI-3
Plant
Broccoli
Lee et al.
(2011)
Limonoids
(obacunone)
EHEC
Plant
Grapefruit
Vikram et al.
(2010)
L-Canavanine
CviR and ExpR
Plant: Alfalfa Medicago sativa
Keshavan
et al. (2005)
Catachin and
naringenin
CviR and RhlR
Plant:
Combretaceae
Combretum
albiflorum
Vandeputte
et al. (2010)
and
Vandeputte
et al. (2011)
Sesquiterpene
lactones
Pseudomonas
aeruginosa
Plant:
Compositae
Centratherum
punctatum
Amaya et al.
(2012)
Ajoene
LuxR family
Plant: Garlic
Allium sativum
Jakobsen
et al.
(2012b)
(continued)
8 Intrusion of Bacterial Quorum-Sensing for Antimicrobial Resistance Mitigation…
Table 8.1 (continued)
Inhibitors
Target
Category
Species
Reference
Kojic acid
LuxR
Fungi
Aspergillus spp.
Dobretsov
et al. (2011)
Patulin and
Penilillic acid
LasR and RhlR
Fungi
Penicillium spp.
Rasmussen
et al. (2005)
Farnesol
(sesquiterpene)
PqsA
Fungi
Candida albicans Cugini et al.
(2007)
Honey and propolis C. violaceum, LasR,
and RhlR
Insect
productions
Bee
Truchado
et al. (2009)
and Bulman
et al. (2011)
Solenopsin A
Rhl circuit
Insect: Fire
ant
Solenopisinvicta
Park et al.
(2008)
Furanone and its
derivatives
LuxR and LuxS
Marine alga
Delisea pulchra
de Nys et al.
(1993) and
Rice et al.
(2002)
Cyclodepsipeptides
(solonomide a, b)
Agr system
Marine
bacteria
Photobacterium
Mansson
et al. (2011)
Benzopyran
CviR, LuxR and LasR Plant
Baccharis
cassinaefolia
Dobretsov
et al. (2011)
Eugenol
CviR, LasR and PQS Plant
Syzygium
aromaticum
Zhou et al.
(2013)
Cinnamaldehyde
and its derivatives
LuxR and AI-2
Plant
Many plants
Niu et al.
(2006),
Brackman
et al. (2008)
and
Brackman
et al.
(2011a)
Quercetin
AI-2 and AI-3
Plant
Broccoli
Lee et al.
(2011)
Limonoids
(obacunone)
EHEC
Plant
Grapefruit
Vikram et al.
(2010)
L-Canavanine
CviR and ExpR
Plant: Alfalfa Medicago sativa
Keshavan
et al. (2005)
Catachin and
naringenin
CviR and RhlR
Plant:
Combretaceae
Combretum
albiflorum
Vandeputte
et al. (2010)
and
Vandeputte
et al. (2011)
Sesquiterpene
lactones
Pseudomonas
aeruginosa
Plant:
Compositae
Centratherum
punctatum
Amaya et al.
(2012)
Ajoene
LuxR family
Plant: Garlic
Allium sativum
Jakobsen
et al.
(2012b)
(continued)
8 Intrusion of Bacterial Quorum-Sensing for Antimicrobial Resistance Mitigation…
