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Table 8.1 Quorum sensing inhibitors and their targets
Inhibitors
Target
Category
Species
Reference
Piericidin A1
CviR
Actinobacteria Streptomyces sp.
Ooka et al.
(2013)
N-(2-Phenylethyl)isobutyramide and
phenylethyl)butyramide
LuxR, CviR and
Vibrio harveyi
Bacteria
Halobacillus
salinus
Teasdale
et al. (2009)
and Teasdale
et al. (2011)
Cyclo-L-proline-Ltyrosine
Chromobacterium
violaceum
Bacteria
Bacillus cereus
D28
Teasdale
et al. (2011)
Diketopiperazines
(dkps)
CviR and LuxR
Bacteria
Marinobacter sp.
SK-3
Abed et al.
(2013)
Yayurea A and B
LuxN
Bacteria
Staphylococcus
delphini
Chu et al.
(2013b)
Cis-9-octadecenoic
acid
CviR
Bacteria
Stenotrophomonas
maltophilia BJ01
Singh et al.
(2013)
Protoanemonin
LasR
Bacteria
Pseudomonas spp. Bobadilla
Fazzini et al.
(2013)
Cyclic dipeptides:
Cyclo (L-PheL-pro)
and cyclo
(L-Tyr-L-pro)
Agr system
Bacteria
Lactobacillus
reuteri
Li et al.
(2011)
Brominated
alkaloids
compounds
CepR and LuxR
Bryozoan
Flustra foliacea
Peters et al.
(2003)
Cembranoids
Lux R and V. harveyi Coral
Pseudoplexaura
flagellosa and
Eunicea knighti
Tello et al.
(2011) and
Tello et al.
(2012)
Tumonoic acid F
V. harveyi
Cyanobacteria Blennothrix
cantharidosmum
Clark et al.
(2008)
8-epi-malyngamide
C and lyngbic acid
LasR
Cyanobacteria Lyngbya
majuscula
Kwan et al.
(2010)
Lyngbyoic acid
LasR
Cyanobacteria L. majuscula
Kwan et al.
(2011)
Malyngolide
CviR and LasR
Cyanobacteria L. majuscula
Dobretsov
et al. (2010)
Honaucins A-C
LuxR
Cyanobacteria Leptolyngbya
crossbyana
Choi et al.
(2012)
Pitinoic acid A
LasR
Cyanobacteria Lyngbya sp
Montaser
et al. (2013)
Peptides
(microcolins A and
B)
LuxR
Cyanobacteria Lyngbya sp
Dobretsov
et al. (2011)
Crude extracts
LasR
Fungi
Penicillium
atramentosum
Wang et al.
(2011)
(continued)
S. Kumar et al.