62
Xenopus
Kjolby, R.A.S., and R.M. Harland. 2017. Genome-wide identif -
cation of Wnt/beta-catenin transcriptional targets during
Xenopus gastrulation. Dev Biol. 426:165–175.
Kjolby, R.A.S., M. Truchado-Garcia, S. Iruvanti, and R.M. Harland.
2019. Integration of Wnt and FGF signaling in the Xenopus
gastrula at TCF and Ets binding sites shows the importance
of short-range repression by TCF in patterning the marginal
zone. Development. 146.
Koide, T., M. Downes, R.A. Chandraratna, B. Blumberg, and
K. Umesono. 2001. Active repression of RAR signaling is
required for head formation. Genes Dev. 15:2111–2121.
Kolm, P.J., V. Apekin, and H. Sive. 1997. Xenopus hindbrain patterning requires retinoid signaling. Dev Biol. 192:1–16.
Komiya, Y., N. Mandrekar, A. Sato, I.B. Dawid, and R. Habas.
2014. Custos controls beta-catenin to regulate head development during vertebrate embryogenesis. Proc Natl Acad Sci
U S A. 111:13099–13104.
Lamb, T.M., and R.M. Harland. 1995. Fibroblast growth factor is a direct neural inducer, which combined with noggin
generates anterior-posterior neural pattern. Development.
121:3627–3636.
Lamb, T.M., A.K. Knecht, W.C. Smith, S.E. Stachel, A.N.
Economides, N. Stahl, G.D. Yancopolous, and R.M. Harland.
1993. Neural induction by the secreted polypeptide noggin.
Science. 262:713–718.
Lea, R., N. Papalopulu, E. Amaya, and K. Dorey. 2009. Temporal
and spatial expression of FGF ligands and receptors during
Xenopus development. Dev Dyn. 238:1467–1479.
Lee, H., S.M. Cheong, W. Han, Y. Koo, S.B. Jo, G.S. Cho, J.S.
Yang, S. Kim, and J.K. Han. 2018. Head formation requires
Dishevelled degradation that is mediated by March2 in concert with Dapper1. Development. 145.
Leyns, L., T. Bouwmeester, S.H. Kim, S. Piccolo, and E.M. De
Robertis. 1997. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell. 88:747–756.
Lin, K., S. Wang, M.A. Julius, J. Kitajewski, M. Moos, Jr., and F.P.
Luyten. 1997. The cysteine-rich frizzled domain of Frzb-1 is
required and suffcient for modulation of Wnt signaling. Proc
Natl Acad Sci U S A. 94:11196–11200.
Lloret-Vilaspasa, F., H.J. Jansen, K. de Roos, R.A. Chandraratna,
M.H. Zile, C.D. Stern, and A.J. Durston. 2010. Retinoid
signalling is required for information transfer from mesoderm to neuroectoderm during gastrulation. Int J Dev Biol.
54:599–608.
Lombardo, A., H.V. Isaacs, and J.M. Slack. 1998. Expression and
functions of FGF-3 in Xenopus development. Int J Dev Biol.
42:1101–1107.
Lombardo, A., and J.M. Slack. 1998. Postgastrulation effects of
fbroblast growth factor on Xenopus development. Dev Dyn.
212:75–85.
Lou, X., P. Fang, S. Li, R.Y. Hu, K.M. Kuerner, H. Steinbeisser,
and X. Ding. 2006. Xenopus Tbx6 mediates posterior patterning via activation of Wnt and FGF signalling. Cell Res.
16:771–779.
Mangold, O. 1933. Uber die Inducktionsfahigkeit der verschiedenen
Bezirke der Neurula von Urodelen. Naturwissenshaf en.
43:761–766.
Mao, B., W. Wu, G. Davidson, J. Marhold, M. Li, B.M. Mechler,
H. Delius, D. Hoppe, P. Stannek, C. Walter, A. Glinka, and
C. Niehrs. 2002. Kremen proteins are Dickkopf receptors
that regulate Wnt/beta-catenin signalling. Nature. 417:664–
667.
Mao, B., W. Wu, Y. Li, D. Hoppe, P. Stannek, A. Glinka, and C.
Niehrs. 2001. LDL-receptor-related protein 6 is a receptor
for Dickkopf proteins. Nature. 411:321–325.
McGrew, L.L., S. Hoppler, and R.T. Moon. 1997. Wnt and FGF
pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus. Mech Dev. 69:105–114.
McGrew, L.L., C.J. Lai, and R.T. Moon. 1995. Specifcation of the
anteroposterior neural axis through synergistic interaction of
the Wnt signaling cascade with noggin and follistatin. Dev
Biol. 172:337–342.
McLin, V.A., S.A. Rankin, and A.M. Zorn. 2007. Repression of
Wnt/beta-catenin signaling in the anterior endoderm is
essential for liver and pancreas development. Development.
134:2207–2217.
McMahon, A.P., and R.T. Moon. 1989. Ectopic expression of the
proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell. 58:1075–1084.
Michiue, T., A. Fukui, A. Yukita, K. Sakurai, H. Danno, A. Kikuchi,
and M. Asashima. 2004. XIdax, an inhibitor of the canonical
Wnt pathway, is required for anterior neural structure formation in Xenopus. Dev Dyn. 230:79–90.
Miyagi, A., T. Negishi, T.S. Yamamoto, and N. Ueno. 2015. G
protein-coupled receptors Flop1 and Flop2 inhibit Wnt/betacatenin signaling and are essential for head formation in
Xenopus. Dev Biol. 407:131–144.
Nieuwkoop, P.D. 1952a. Activation and organization of the central
nervous system in amphibians. Part I: Induction and activation. J. Exp. Zool. 120:1–31.
Nieuwkoop, P.D. 1952b. Activation and organization of the central
nervous system in amphibians. Part II: Differentiation and
organization. J. Exp. Zool. 120:33–81.
Nieuwkoop, P.D. 1952c. Activation and organization of the central
nervous system in amphibians. Part III: Synthesis of a working hypothesis. J. Exp. Zool. 120:83–108.
Okada, Y.K., and H. Takaya. 1942. Experimental investigation of
regional differences in the inductive capacity of the organizer. Proc. Imp. Acad. (Tokyo). 18:505–513.
Papalopulu, N., J.D. Clarke, L. Bradley, D. Wilkinson, R. Krumlauf,
and N. Holder. 1991a. Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in
Xenopus embryos. Development. 113:1145–1158.
Papalopulu, N., and C. Kintner. 1996. A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the
timing of neuronal differentiation in Xenopus neuroectoderm. Development. 122:3409–3418.
Papalopulu, N., R. Lovell-Badge, and R. Krumlauf. 1991b. The
expression of murine Hox-2 genes is dependent on the differentiation pathway and displays a collinear sensitivity to
retinoic acid in F9 cells and Xenopus embryos. Nucleic Acids
Res. 19:5497–5506.
Pera, E.M., and E.M. De Robertis. 2000. A direct screen for
secreted proteins in Xenopus embryos identif es distinct
activities for the Wnt antagonists Crescent and Frzb-1. Mech
Dev. 96:183–195.
Pfeffer, P.L., and E.M. De Robertis. 1994. Regional specif city of
RAR gamma isoforms in Xenopus development. Mech Dev.
45:147–153.
Piccolo, S., E. Agius, L. Leyns, S. Bhattacharyya, H. Grunz, T.
Bouwmeester, and E.M. De Robertis. 1999. The head inducer
Cerberus is a multifunctional antagonist of Nodal, BMP and
Wnt signals. Nature. 397:707–710.
Pillemer, G., M. Epstein, B. Blumberg, J.K. Yisraeli, E.M. De
Robertis, H. Steinbeisser, and A. Fainsod. 1998. Nested expression and sequential downregulation of the Xenopus caudal
genes along the anterior-posterior axis. Mech Dev. 71:193–196.
Pinho, S., and C. Niehrs. 2007. Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. Differentiation.
75:957–967.
Xenopus
Kjolby, R.A.S., and R.M. Harland. 2017. Genome-wide identif -
cation of Wnt/beta-catenin transcriptional targets during
Xenopus gastrulation. Dev Biol. 426:165–175.
Kjolby, R.A.S., M. Truchado-Garcia, S. Iruvanti, and R.M. Harland.
2019. Integration of Wnt and FGF signaling in the Xenopus
gastrula at TCF and Ets binding sites shows the importance
of short-range repression by TCF in patterning the marginal
zone. Development. 146.
Koide, T., M. Downes, R.A. Chandraratna, B. Blumberg, and
K. Umesono. 2001. Active repression of RAR signaling is
required for head formation. Genes Dev. 15:2111–2121.
Kolm, P.J., V. Apekin, and H. Sive. 1997. Xenopus hindbrain patterning requires retinoid signaling. Dev Biol. 192:1–16.
Komiya, Y., N. Mandrekar, A. Sato, I.B. Dawid, and R. Habas.
2014. Custos controls beta-catenin to regulate head development during vertebrate embryogenesis. Proc Natl Acad Sci
U S A. 111:13099–13104.
Lamb, T.M., and R.M. Harland. 1995. Fibroblast growth factor is a direct neural inducer, which combined with noggin
generates anterior-posterior neural pattern. Development.
121:3627–3636.
Lamb, T.M., A.K. Knecht, W.C. Smith, S.E. Stachel, A.N.
Economides, N. Stahl, G.D. Yancopolous, and R.M. Harland.
1993. Neural induction by the secreted polypeptide noggin.
Science. 262:713–718.
Lea, R., N. Papalopulu, E. Amaya, and K. Dorey. 2009. Temporal
and spatial expression of FGF ligands and receptors during
Xenopus development. Dev Dyn. 238:1467–1479.
Lee, H., S.M. Cheong, W. Han, Y. Koo, S.B. Jo, G.S. Cho, J.S.
Yang, S. Kim, and J.K. Han. 2018. Head formation requires
Dishevelled degradation that is mediated by March2 in concert with Dapper1. Development. 145.
Leyns, L., T. Bouwmeester, S.H. Kim, S. Piccolo, and E.M. De
Robertis. 1997. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell. 88:747–756.
Lin, K., S. Wang, M.A. Julius, J. Kitajewski, M. Moos, Jr., and F.P.
Luyten. 1997. The cysteine-rich frizzled domain of Frzb-1 is
required and suffcient for modulation of Wnt signaling. Proc
Natl Acad Sci U S A. 94:11196–11200.
Lloret-Vilaspasa, F., H.J. Jansen, K. de Roos, R.A. Chandraratna,
M.H. Zile, C.D. Stern, and A.J. Durston. 2010. Retinoid
signalling is required for information transfer from mesoderm to neuroectoderm during gastrulation. Int J Dev Biol.
54:599–608.
Lombardo, A., H.V. Isaacs, and J.M. Slack. 1998. Expression and
functions of FGF-3 in Xenopus development. Int J Dev Biol.
42:1101–1107.
Lombardo, A., and J.M. Slack. 1998. Postgastrulation effects of
fbroblast growth factor on Xenopus development. Dev Dyn.
212:75–85.
Lou, X., P. Fang, S. Li, R.Y. Hu, K.M. Kuerner, H. Steinbeisser,
and X. Ding. 2006. Xenopus Tbx6 mediates posterior patterning via activation of Wnt and FGF signalling. Cell Res.
16:771–779.
Mangold, O. 1933. Uber die Inducktionsfahigkeit der verschiedenen
Bezirke der Neurula von Urodelen. Naturwissenshaf en.
43:761–766.
Mao, B., W. Wu, G. Davidson, J. Marhold, M. Li, B.M. Mechler,
H. Delius, D. Hoppe, P. Stannek, C. Walter, A. Glinka, and
C. Niehrs. 2002. Kremen proteins are Dickkopf receptors
that regulate Wnt/beta-catenin signalling. Nature. 417:664–
667.
Mao, B., W. Wu, Y. Li, D. Hoppe, P. Stannek, A. Glinka, and C.
Niehrs. 2001. LDL-receptor-related protein 6 is a receptor
for Dickkopf proteins. Nature. 411:321–325.
McGrew, L.L., S. Hoppler, and R.T. Moon. 1997. Wnt and FGF
pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus. Mech Dev. 69:105–114.
McGrew, L.L., C.J. Lai, and R.T. Moon. 1995. Specifcation of the
anteroposterior neural axis through synergistic interaction of
the Wnt signaling cascade with noggin and follistatin. Dev
Biol. 172:337–342.
McLin, V.A., S.A. Rankin, and A.M. Zorn. 2007. Repression of
Wnt/beta-catenin signaling in the anterior endoderm is
essential for liver and pancreas development. Development.
134:2207–2217.
McMahon, A.P., and R.T. Moon. 1989. Ectopic expression of the
proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell. 58:1075–1084.
Michiue, T., A. Fukui, A. Yukita, K. Sakurai, H. Danno, A. Kikuchi,
and M. Asashima. 2004. XIdax, an inhibitor of the canonical
Wnt pathway, is required for anterior neural structure formation in Xenopus. Dev Dyn. 230:79–90.
Miyagi, A., T. Negishi, T.S. Yamamoto, and N. Ueno. 2015. G
protein-coupled receptors Flop1 and Flop2 inhibit Wnt/betacatenin signaling and are essential for head formation in
Xenopus. Dev Biol. 407:131–144.
Nieuwkoop, P.D. 1952a. Activation and organization of the central
nervous system in amphibians. Part I: Induction and activation. J. Exp. Zool. 120:1–31.
Nieuwkoop, P.D. 1952b. Activation and organization of the central
nervous system in amphibians. Part II: Differentiation and
organization. J. Exp. Zool. 120:33–81.
Nieuwkoop, P.D. 1952c. Activation and organization of the central
nervous system in amphibians. Part III: Synthesis of a working hypothesis. J. Exp. Zool. 120:83–108.
Okada, Y.K., and H. Takaya. 1942. Experimental investigation of
regional differences in the inductive capacity of the organizer. Proc. Imp. Acad. (Tokyo). 18:505–513.
Papalopulu, N., J.D. Clarke, L. Bradley, D. Wilkinson, R. Krumlauf,
and N. Holder. 1991a. Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in
Xenopus embryos. Development. 113:1145–1158.
Papalopulu, N., and C. Kintner. 1996. A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the
timing of neuronal differentiation in Xenopus neuroectoderm. Development. 122:3409–3418.
Papalopulu, N., R. Lovell-Badge, and R. Krumlauf. 1991b. The
expression of murine Hox-2 genes is dependent on the differentiation pathway and displays a collinear sensitivity to
retinoic acid in F9 cells and Xenopus embryos. Nucleic Acids
Res. 19:5497–5506.
Pera, E.M., and E.M. De Robertis. 2000. A direct screen for
secreted proteins in Xenopus embryos identif es distinct
activities for the Wnt antagonists Crescent and Frzb-1. Mech
Dev. 96:183–195.
Pfeffer, P.L., and E.M. De Robertis. 1994. Regional specif city of
RAR gamma isoforms in Xenopus development. Mech Dev.
45:147–153.
Piccolo, S., E. Agius, L. Leyns, S. Bhattacharyya, H. Grunz, T.
Bouwmeester, and E.M. De Robertis. 1999. The head inducer
Cerberus is a multifunctional antagonist of Nodal, BMP and
Wnt signals. Nature. 397:707–710.
Pillemer, G., M. Epstein, B. Blumberg, J.K. Yisraeli, E.M. De
Robertis, H. Steinbeisser, and A. Fainsod. 1998. Nested expression and sequential downregulation of the Xenopus caudal
genes along the anterior-posterior axis. Mech Dev. 71:193–196.
Pinho, S., and C. Niehrs. 2007. Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. Differentiation.
75:957–967.