274
Xenopus
Paraiso, K. D., Cho, J. S., Yong, J., & Cho, K. (2020). Early
Xenopus gene regulatory programs, chromatin states, and
the role of maternal transcription factors. Current Topics in
Developmental Biology, 139, 35–60.
Pearl, E. J., Bilogan, C. K., Mukhi, S., Brown, D. D., & Horb, M.
E. (2009). Xenopus pancreas development. Developmental
Dynamics, 238 (6), 1271–1286.
Pearl, E. J., Jarikji, Z., & Horb, M. E. (2011). Functional analysis of
Rfx6 and mutant variants associated with neonatal diabetes.
Developmental Biology, 351 (1), 135–145.
Poll, A. V., Pierreux, C. E., Lokmane, L., Haumaitre, C., Achouri, Y.,
Jacquemin, P., Rousseau, G. G., Cereghini, S., & Lemaigre,
F. P. (2006). A vHNF1/TCF2-HNF6 cascade regulates the
transcription factor network that controls generation of pancreatic precursor cells. Diabetes, 55 (1), 61–69.
Rankin, S. A., Gallas, A. L., Neto, A., Gómez-Skarmeta, J. L., &
Zorn, A. M. (2012). Suppression of Bmp4 signaling by
the zinc-fnger repressors Osr1 and Osr2 is required for
Wnt/β-catenin-mediated lung specifcation in Xenopus.
Development, 139 (16), 3010–3020.
Rankin, S. A., Han, L., McCracken, K. W., Kenny, A. P., Anglin,
C. T., Grigg, E. A., Crawford, C. M., Wells, J. M., Shannon,
J. M., & Zorn, A. M. (2016). A retinoic acid-Hedgehog cascade coordinates mesoderm-inducing signals and endoderm
competence during lung specif cation. Cell Reports, 16(1),
66–78.
Rankin, S. A., Kormish, J., Kofron, M., Jegga, A., & Zorn, A.
M. (2011). A gene regulatory network controlling hhex
transcription in the anterior endoderm of the organizer.
Developmental Biology, 351 (2), 297–310.
Rankin, S. A., McCracken, K. W., Luedeke, D. M., Han, L., Wells,
J. M., Shannon, J. M., & Zorn, A. M. (2018). Timing is
everything: Reiterative Wnt, BMP and RA signaling regulate
developmental competence during endoderm organogenesis.
Developmental Biology, 434 (1), 121–132.
Rankin, S. A., Thi Tran, H., Wlizla, M., Mancini, P., Shif ey, E. T.,
Bloor, S. D., Han, L., Vleminckx, K., Wert, S. E., & Zorn, A.
M. (2015). A molecular atlas of Xenopus respiratory system
development. Developmental Dynamics, 244 (1), 69–85.
Reed, R. A., Womble, M. A., Dush, M. K., Tull, R. R., Bloom,
S. K., Morckel, A. R., Devlin, E. W., & Nascone-Yoder,
N. M. (2009). Morphogenesis of the primitive gut tube
is generated by Rho/ROCK/myosin II-mediated endoderm rearrangements. Developmental Dynamics, 238(12),
3111–3125.
Reich, S., & Weinstein, D. C. (2019). Repression of inappropriate gene expression in the vertebrate embryonic ectoderm.
Genes, 10 (11), 895.
Rex, M., Hilton, E., & Old, R. (2002). Multiple interactions
between maternally-activated signalling pathways control
Xenopus nodal-related genes. The International Journal of
Developmental Biology, 46 (2), 217–226.
Rodríguez-Seguel, E., Mah, N., Naumann, H., Pongrac, I. M.,
Cerdá-Esteban, N., Fontaine, J. F., Wang, Y., Chen, W.,
Andrade-Navarro, M. A., & Spagnoli, F. M. (2013).
Mutually exclusive signaling signatures defne the hepatic
and pancreatic progenitor cell lineage divergence. Genes &
Development, 27 (17), 1932–1946.
Rose, C. S., & James, B. (2013). Plasticity of lung development
in the amphibian, Xenopus laevis. Biology Open, 2(12),
1324–1335.
Runck, L. A., Method, A., Bischoff, A., Levitt, M., Peña, A.,
Collins, M. H., Gupta, A., Shanmukhappa, S., Wells, J. M., &
Guasch, G. (2014). Defning the molecular pathologies in
cloaca malformation: similarities between mouse and human.
Disease Models & Mechanisms, 7 (4), 483–493.
Salanga, M. C., & Horb, M. E. (2015). Xenopus as a model for
GI/pancreas disease. Current Pathobiology Reports, 3(2),
137–145.
Sander, V., Reversade, B., & De Robertis, E. M. (2007). The opposing homeobox genes Goosecoid and Vent1/2 self-regulate
Xenopus patterning. The EMBO Journal, 26 (12), 2955–2965.
Shifey, E. T., Kenny, A. P., Rankin, S. A., & Zorn, A. M. (2012).
Prolonged FGF signaling is necessary for lung and liver
induction in Xenopus. BMC Developmental Biology, 12, 27.
Shiotsugu, J., Katsuyama, Y., Arima, K., Baxter, A., Koide, T.,
Song, J., Chandraratna, R. A., & Blumberg, B. (2004).
Multiple points of interaction between retinoic acid and FGF
signaling during embryonic axis formation. Development,
131 (11), 2653–2667.
Sinner, D., Kirilenko, P., Rankin, S., Wei, E., Howard, L., Kofron,
M., Heasman, J., Woodland, H. R., & Zorn, A. M. (2006).
Global analysis of the transcriptional network controlling Xenopus endoderm formation. Development, 133(10),
1955–1966.
Smith, J. C., Price, B. M., Van Nimmen, K., & Huylebroeck, D.
(1990). Identifcation of a potent Xenopus mesoderm-inducing
factor as a homologue of activin A. Nature, 345(6277),
729–731.
Smith, S. B., Qu, H. Q., Taleb, N., Kishimoto, N. Y., Scheel, D.
W., Lu, Y., Patch, A. M., Grabs, R., Wang, J., Lynn, F. C.,
Miyatsuka, T., Mitchell, J., Seerke, R., Désir, J., Vanden
Eijnden, S., Abramowicz, M., Kacet, N., Weill, J., Renard,
M. E., Gentile, M., Hansen, I., Dewar, K., Hattersley, A. T.,
Wang, R., Wilson, M. E., Johnson, J. D., Polychronakos,
C., & German, M. S. (2010). Rfx6 directs islet formation and
insulin production in mice and humans. Nature, 463(7282),
775–780.
Spagnoli, F. M., & Brivanlou, A. H. (2008). The Gata5 target,
TGIF2, defnes the pancreatic region by modulating BMP
signals within the endoderm. Development, 135 (3), 451–461.
Stafford, D., Hornbruch, A., Mueller, P. R., & Prince, V. E. (2004).
A conserved role for retinoid signaling in vertebrate pancreas
development. Development Genes and Evolution, 214(9),
432–441.
Steimle, J. D., Rankin, S. A., Slagle, C. E., Bekeny, J., Rydeen,
A. B., Chan, S. S., Kweon, J., Yang, X. H., Ikegami, K.,
Nadadur, R. D., Rowton, M., Hoffmann, A. D., Lazarevic,
S., Thomas, W., Boyle Anderson, E., Horb, M. E., LunaZurita, L., Ho, R. K., Kyba, M., Jensen, B., Zorn, A. M.,
Conlon, F. L., & Moskowitz, I. P. (2018). Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. Proceedings of the National Academy of
Sciences of the United States of America, 115 (45), E10615–
E10624.
Stevens, M. L., Chaturvedi, P., Rankin, S. A., Macdonald, M.,
Jagannathan, S., Yukawa, M., Barski, A., & Zorn, A. M.
(2017). Genomic integration of Wnt/β-catenin and BMP/
Smad1 signaling coordinates foregut and hindgut transcriptional programs. Development, 144 (7), 1283–1295.
Tao, Q., Yokota, C., Puck, H., Kofron, M., Birsoy, B., Yan, D.,
Asashima, M., Wylie, C. C., Lin, X., & Heasman, J. (2005).
Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos. Cell,
120 (6), 857–871.
Teo, A. K., Tsuneyoshi, N., Hoon, S., Tan, E. K., Stanton,
L. W., Wright, C. V., & Dunn, N. R. (2015). PDX1 binds
and represses hepatic genes to ensure robust pancreatic
Xenopus
Paraiso, K. D., Cho, J. S., Yong, J., & Cho, K. (2020). Early
Xenopus gene regulatory programs, chromatin states, and
the role of maternal transcription factors. Current Topics in
Developmental Biology, 139, 35–60.
Pearl, E. J., Bilogan, C. K., Mukhi, S., Brown, D. D., & Horb, M.
E. (2009). Xenopus pancreas development. Developmental
Dynamics, 238 (6), 1271–1286.
Pearl, E. J., Jarikji, Z., & Horb, M. E. (2011). Functional analysis of
Rfx6 and mutant variants associated with neonatal diabetes.
Developmental Biology, 351 (1), 135–145.
Poll, A. V., Pierreux, C. E., Lokmane, L., Haumaitre, C., Achouri, Y.,
Jacquemin, P., Rousseau, G. G., Cereghini, S., & Lemaigre,
F. P. (2006). A vHNF1/TCF2-HNF6 cascade regulates the
transcription factor network that controls generation of pancreatic precursor cells. Diabetes, 55 (1), 61–69.
Rankin, S. A., Gallas, A. L., Neto, A., Gómez-Skarmeta, J. L., &
Zorn, A. M. (2012). Suppression of Bmp4 signaling by
the zinc-fnger repressors Osr1 and Osr2 is required for
Wnt/β-catenin-mediated lung specifcation in Xenopus.
Development, 139 (16), 3010–3020.
Rankin, S. A., Han, L., McCracken, K. W., Kenny, A. P., Anglin,
C. T., Grigg, E. A., Crawford, C. M., Wells, J. M., Shannon,
J. M., & Zorn, A. M. (2016). A retinoic acid-Hedgehog cascade coordinates mesoderm-inducing signals and endoderm
competence during lung specif cation. Cell Reports, 16(1),
66–78.
Rankin, S. A., Kormish, J., Kofron, M., Jegga, A., & Zorn, A.
M. (2011). A gene regulatory network controlling hhex
transcription in the anterior endoderm of the organizer.
Developmental Biology, 351 (2), 297–310.
Rankin, S. A., McCracken, K. W., Luedeke, D. M., Han, L., Wells,
J. M., Shannon, J. M., & Zorn, A. M. (2018). Timing is
everything: Reiterative Wnt, BMP and RA signaling regulate
developmental competence during endoderm organogenesis.
Developmental Biology, 434 (1), 121–132.
Rankin, S. A., Thi Tran, H., Wlizla, M., Mancini, P., Shif ey, E. T.,
Bloor, S. D., Han, L., Vleminckx, K., Wert, S. E., & Zorn, A.
M. (2015). A molecular atlas of Xenopus respiratory system
development. Developmental Dynamics, 244 (1), 69–85.
Reed, R. A., Womble, M. A., Dush, M. K., Tull, R. R., Bloom,
S. K., Morckel, A. R., Devlin, E. W., & Nascone-Yoder,
N. M. (2009). Morphogenesis of the primitive gut tube
is generated by Rho/ROCK/myosin II-mediated endoderm rearrangements. Developmental Dynamics, 238(12),
3111–3125.
Reich, S., & Weinstein, D. C. (2019). Repression of inappropriate gene expression in the vertebrate embryonic ectoderm.
Genes, 10 (11), 895.
Rex, M., Hilton, E., & Old, R. (2002). Multiple interactions
between maternally-activated signalling pathways control
Xenopus nodal-related genes. The International Journal of
Developmental Biology, 46 (2), 217–226.
Rodríguez-Seguel, E., Mah, N., Naumann, H., Pongrac, I. M.,
Cerdá-Esteban, N., Fontaine, J. F., Wang, Y., Chen, W.,
Andrade-Navarro, M. A., & Spagnoli, F. M. (2013).
Mutually exclusive signaling signatures defne the hepatic
and pancreatic progenitor cell lineage divergence. Genes &
Development, 27 (17), 1932–1946.
Rose, C. S., & James, B. (2013). Plasticity of lung development
in the amphibian, Xenopus laevis. Biology Open, 2(12),
1324–1335.
Runck, L. A., Method, A., Bischoff, A., Levitt, M., Peña, A.,
Collins, M. H., Gupta, A., Shanmukhappa, S., Wells, J. M., &
Guasch, G. (2014). Defning the molecular pathologies in
cloaca malformation: similarities between mouse and human.
Disease Models & Mechanisms, 7 (4), 483–493.
Salanga, M. C., & Horb, M. E. (2015). Xenopus as a model for
GI/pancreas disease. Current Pathobiology Reports, 3(2),
137–145.
Sander, V., Reversade, B., & De Robertis, E. M. (2007). The opposing homeobox genes Goosecoid and Vent1/2 self-regulate
Xenopus patterning. The EMBO Journal, 26 (12), 2955–2965.
Shifey, E. T., Kenny, A. P., Rankin, S. A., & Zorn, A. M. (2012).
Prolonged FGF signaling is necessary for lung and liver
induction in Xenopus. BMC Developmental Biology, 12, 27.
Shiotsugu, J., Katsuyama, Y., Arima, K., Baxter, A., Koide, T.,
Song, J., Chandraratna, R. A., & Blumberg, B. (2004).
Multiple points of interaction between retinoic acid and FGF
signaling during embryonic axis formation. Development,
131 (11), 2653–2667.
Sinner, D., Kirilenko, P., Rankin, S., Wei, E., Howard, L., Kofron,
M., Heasman, J., Woodland, H. R., & Zorn, A. M. (2006).
Global analysis of the transcriptional network controlling Xenopus endoderm formation. Development, 133(10),
1955–1966.
Smith, J. C., Price, B. M., Van Nimmen, K., & Huylebroeck, D.
(1990). Identifcation of a potent Xenopus mesoderm-inducing
factor as a homologue of activin A. Nature, 345(6277),
729–731.
Smith, S. B., Qu, H. Q., Taleb, N., Kishimoto, N. Y., Scheel, D.
W., Lu, Y., Patch, A. M., Grabs, R., Wang, J., Lynn, F. C.,
Miyatsuka, T., Mitchell, J., Seerke, R., Désir, J., Vanden
Eijnden, S., Abramowicz, M., Kacet, N., Weill, J., Renard,
M. E., Gentile, M., Hansen, I., Dewar, K., Hattersley, A. T.,
Wang, R., Wilson, M. E., Johnson, J. D., Polychronakos,
C., & German, M. S. (2010). Rfx6 directs islet formation and
insulin production in mice and humans. Nature, 463(7282),
775–780.
Spagnoli, F. M., & Brivanlou, A. H. (2008). The Gata5 target,
TGIF2, defnes the pancreatic region by modulating BMP
signals within the endoderm. Development, 135 (3), 451–461.
Stafford, D., Hornbruch, A., Mueller, P. R., & Prince, V. E. (2004).
A conserved role for retinoid signaling in vertebrate pancreas
development. Development Genes and Evolution, 214(9),
432–441.
Steimle, J. D., Rankin, S. A., Slagle, C. E., Bekeny, J., Rydeen,
A. B., Chan, S. S., Kweon, J., Yang, X. H., Ikegami, K.,
Nadadur, R. D., Rowton, M., Hoffmann, A. D., Lazarevic,
S., Thomas, W., Boyle Anderson, E., Horb, M. E., LunaZurita, L., Ho, R. K., Kyba, M., Jensen, B., Zorn, A. M.,
Conlon, F. L., & Moskowitz, I. P. (2018). Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. Proceedings of the National Academy of
Sciences of the United States of America, 115 (45), E10615–
E10624.
Stevens, M. L., Chaturvedi, P., Rankin, S. A., Macdonald, M.,
Jagannathan, S., Yukawa, M., Barski, A., & Zorn, A. M.
(2017). Genomic integration of Wnt/β-catenin and BMP/
Smad1 signaling coordinates foregut and hindgut transcriptional programs. Development, 144 (7), 1283–1295.
Tao, Q., Yokota, C., Puck, H., Kofron, M., Birsoy, B., Yan, D.,
Asashima, M., Wylie, C. C., Lin, X., & Heasman, J. (2005).
Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos. Cell,
120 (6), 857–871.
Teo, A. K., Tsuneyoshi, N., Hoon, S., Tan, E. K., Stanton,
L. W., Wright, C. V., & Dunn, N. R. (2015). PDX1 binds
and represses hepatic genes to ensure robust pancreatic