275
Digestive and Respiratory System
commitment in differentiating human embryonic stem cells.
Stem Cell Reports, 4 (4), 578–590.
Tran, H. T., Sekkali, B., Van Imschoot, G., Janssens, S., &
Vleminckx, K. (2010). Wnt/beta-catenin signaling is
involved in the induction and maintenance of primitive
hematopoiesis in the vertebrate embryo. Proceedings of
the National Academy of Sciences of the United States of
America, 107 (37), 16160–16165.
Trisno, S. L., Philo, K., McCracken, K. W., Catá, E. M., RuizTorres, S., Rankin, S. A., Han, L., Nasr, T., Chaturvedi, P.,
Rothenberg, M. E., Mandegar, M. A., Wells, S. I., Zorn,
A. M., & Wells, J. M. (2018). Esophageal organoids from
human pluripotent stem cells delineate Sox2 functions during esophageal specif cation. Cell Stem Cell, 23 (4), 501–515.
e7.
Twaroski, K., Mallanna, S. K., Jing, R., DiFurio, F., Urick, A., &
Duncan, S. A. (2015). FGF2 mediates hepatic progenitor
cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1. Genes &
Development, 29 (23), 2463–2474.
Vinckier, N. K., Patel, N. A., Geusz, R. J., Wang, A., Wang, J.,
Matta, I., Harrington, A. R., Wortham, M., Wetton, N.,
Wang, J., Jhala, U. S., Rosenfeld, M. G., Benner, C. W.,
Shih, H. P., & Sander, M. (2020). LSD1-mediated enhancer
silencing attenuates retinoic acid signalling during pancreatic
endocrine cell development. Nature Communications, 11(1),
2082.
Wandzioch, E., & Zaret, K. S. (2009). Dynamic signaling network
for the specifcation of embryonic pancreas and liver progenitors. Science, 324 (5935), 1707–1710.
Wang, A., Yue, F., Li, Y., Xie, R., Harper, T., Patel, N. A., Muth,
K., Palmer, J., Qiu, Y., Wang, J., Lam, D. K., Raum, J. C.,
Stoffers, D. A., Ren, B., & Sander, M. (2015). Epigenetic
priming of enhancers predicts developmental competence of
hESC-derived endodermal lineage intermediates. Cell Stem
Cell, 16 (4), 386–399.
Wang, J. H., Deimling, S. J., D’Alessandro, N. E., Zhao, L.,
Possmayer, F., & Drysdale, T. A. (2011). Retinoic acid is a key
regulatory switch determining the difference between lung
and thyroid fates in Xenopus laevis. BMC Developmental
Biology, 11, 75.
Wang, X., Sterr, M., Burtscher, I., Chen, S., Hieronimus, A.,
Machicao, F., Staiger, H., Häring, H. U., Lederer, G.,
Meitinger, T., Cernilogar, F. M., Schotta, G., Irmler, M.,
Beckers, J., Hrabě de Angelis, M., Ray, M., Wright, C.,
Bakhti, M., & Lickert, H. (2018). Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Molecular Metabolism, 9, 57–68.
Wright, C. V., Schnegelsberg, P., De Robertis, E. M. (1989, April).
XlHbox 8: A novel Xenopus homeo protein restricted to a
narrow band of endoderm. Development, 105 (4), 787–794.
Wylie, C. C., Snape, A., Heasman, J., & Smith, J. C. (1987). Vegetal
pole cells and commitment to form endoderm in Xenopus
laevis. Developmental Biology, 119 (2), 496–502.
Xanthos, J. B., Kofron, M., Wylie, C., & Heasman, J. (2001).
Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis. Development, 128(2),
167–180.
Xanthos, J. B., Kofron, M., Tao, Q., Schaible, K., Wylie, C., &
Heasman, J. (2002). The roles of three signaling pathways
in the formation and function of the Spemann organizer.
Development, 129 (17), 4027–4043.
Yasuoka, Y., Suzuki, Y., Takahashi, S., Someya, H., Sudou, N.,
Haramoto, Y., Cho, K. W., Asashima, M., Sugano, S., &
Taira, M. (2014). Occupancy of tissue-specif c cis-regulatory
modules by Otx2 and TLE/Groucho for embryonic head
specif cation. Nature Communications, 5, 4322.
Yasuoka, Y., Tando, Y., Kubokawa, K., & Taira, M. (2019). Evolution
of cis-regulatory modules for the head organizer gene goosecoid in chordates: Comparisons between Branchiostoma and
Xenopus. Zoological Letters, 5, 27.
Zhang, Z., Rankin, S. A., & Zorn, A. M. (2013a). Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation,
morphogenesis and fate of endoderm progenitor cells.
Developmental Biology, 378 (1), 1–12.
Zhang, T., Guo, X., & Chen, Y. (2013b). Retinoic acid-activated
Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus
pancreas, oesophagus, stomach, and duodenum specif cation.
PLoS One, 8 (5), e65058.
Zorn, A. M., Butler, K., & Gurdon, J. B. (1999). Anterior endomesoderm specifcation in Xenopus by Wnt/beta-catenin
and TGF-beta signalling pathways. Developmental Biology,
209 (2), 282–297.
Zorn, A. M., & Wells, J. M. (2009). Vertebrate endoderm development and organ formation. Annual Review of Cell and
Developmental Biology, 25, 221–251.
Digestive and Respiratory System
commitment in differentiating human embryonic stem cells.
Stem Cell Reports, 4 (4), 578–590.
Tran, H. T., Sekkali, B., Van Imschoot, G., Janssens, S., &
Vleminckx, K. (2010). Wnt/beta-catenin signaling is
involved in the induction and maintenance of primitive
hematopoiesis in the vertebrate embryo. Proceedings of
the National Academy of Sciences of the United States of
America, 107 (37), 16160–16165.
Trisno, S. L., Philo, K., McCracken, K. W., Catá, E. M., RuizTorres, S., Rankin, S. A., Han, L., Nasr, T., Chaturvedi, P.,
Rothenberg, M. E., Mandegar, M. A., Wells, S. I., Zorn,
A. M., & Wells, J. M. (2018). Esophageal organoids from
human pluripotent stem cells delineate Sox2 functions during esophageal specif cation. Cell Stem Cell, 23 (4), 501–515.
e7.
Twaroski, K., Mallanna, S. K., Jing, R., DiFurio, F., Urick, A., &
Duncan, S. A. (2015). FGF2 mediates hepatic progenitor
cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1. Genes &
Development, 29 (23), 2463–2474.
Vinckier, N. K., Patel, N. A., Geusz, R. J., Wang, A., Wang, J.,
Matta, I., Harrington, A. R., Wortham, M., Wetton, N.,
Wang, J., Jhala, U. S., Rosenfeld, M. G., Benner, C. W.,
Shih, H. P., & Sander, M. (2020). LSD1-mediated enhancer
silencing attenuates retinoic acid signalling during pancreatic
endocrine cell development. Nature Communications, 11(1),
2082.
Wandzioch, E., & Zaret, K. S. (2009). Dynamic signaling network
for the specifcation of embryonic pancreas and liver progenitors. Science, 324 (5935), 1707–1710.
Wang, A., Yue, F., Li, Y., Xie, R., Harper, T., Patel, N. A., Muth,
K., Palmer, J., Qiu, Y., Wang, J., Lam, D. K., Raum, J. C.,
Stoffers, D. A., Ren, B., & Sander, M. (2015). Epigenetic
priming of enhancers predicts developmental competence of
hESC-derived endodermal lineage intermediates. Cell Stem
Cell, 16 (4), 386–399.
Wang, J. H., Deimling, S. J., D’Alessandro, N. E., Zhao, L.,
Possmayer, F., & Drysdale, T. A. (2011). Retinoic acid is a key
regulatory switch determining the difference between lung
and thyroid fates in Xenopus laevis. BMC Developmental
Biology, 11, 75.
Wang, X., Sterr, M., Burtscher, I., Chen, S., Hieronimus, A.,
Machicao, F., Staiger, H., Häring, H. U., Lederer, G.,
Meitinger, T., Cernilogar, F. M., Schotta, G., Irmler, M.,
Beckers, J., Hrabě de Angelis, M., Ray, M., Wright, C.,
Bakhti, M., & Lickert, H. (2018). Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Molecular Metabolism, 9, 57–68.
Wright, C. V., Schnegelsberg, P., De Robertis, E. M. (1989, April).
XlHbox 8: A novel Xenopus homeo protein restricted to a
narrow band of endoderm. Development, 105 (4), 787–794.
Wylie, C. C., Snape, A., Heasman, J., & Smith, J. C. (1987). Vegetal
pole cells and commitment to form endoderm in Xenopus
laevis. Developmental Biology, 119 (2), 496–502.
Xanthos, J. B., Kofron, M., Wylie, C., & Heasman, J. (2001).
Maternal VegT is the initiator of a molecular network specifying endoderm in Xenopus laevis. Development, 128(2),
167–180.
Xanthos, J. B., Kofron, M., Tao, Q., Schaible, K., Wylie, C., &
Heasman, J. (2002). The roles of three signaling pathways
in the formation and function of the Spemann organizer.
Development, 129 (17), 4027–4043.
Yasuoka, Y., Suzuki, Y., Takahashi, S., Someya, H., Sudou, N.,
Haramoto, Y., Cho, K. W., Asashima, M., Sugano, S., &
Taira, M. (2014). Occupancy of tissue-specif c cis-regulatory
modules by Otx2 and TLE/Groucho for embryonic head
specif cation. Nature Communications, 5, 4322.
Yasuoka, Y., Tando, Y., Kubokawa, K., & Taira, M. (2019). Evolution
of cis-regulatory modules for the head organizer gene goosecoid in chordates: Comparisons between Branchiostoma and
Xenopus. Zoological Letters, 5, 27.
Zhang, Z., Rankin, S. A., & Zorn, A. M. (2013a). Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation,
morphogenesis and fate of endoderm progenitor cells.
Developmental Biology, 378 (1), 1–12.
Zhang, T., Guo, X., & Chen, Y. (2013b). Retinoic acid-activated
Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus
pancreas, oesophagus, stomach, and duodenum specif cation.
PLoS One, 8 (5), e65058.
Zorn, A. M., Butler, K., & Gurdon, J. B. (1999). Anterior endomesoderm specifcation in Xenopus by Wnt/beta-catenin
and TGF-beta signalling pathways. Developmental Biology,
209 (2), 282–297.
Zorn, A. M., & Wells, J. M. (2009). Vertebrate endoderm development and organ formation. Annual Review of Cell and
Developmental Biology, 25, 221–251.