255
Craniofacial Development and Disorders
skeletogenesis highlight ancestral functions in the vertebrate
head.” Development 141 (3):629–38. doi: 10.1242/dev.097261.
Jaskoll, T., G. Abichaker, P. P. Sedghizadeh, et al. 2008.
“Cytomegalovirus induces abnormal chondrogenesis and
osteogenesis during embryonic mandibular development.”
BMC Dev Biol 8:33. doi: 10.1186/1471–213X-8–33.
Johnson, J. M., G. Moonis, G. E. Green, et al. 2011. “Syndromes of
the frst and second branchial arches, part 1: Embryology and
characteristic defects.” AJNR Am J Neuroradiol 32 (1):14–
19. doi: 10.3174/ajnr.A2072.
Kalcheim, C. 2018. “Neural crest emigration: From start to stop.”
Genesis 56 (6–7):e23090. doi: 10.1002/dvg.23090.
Kennedy, A. E., and A. J. Dickinson. 2012. “Median facial clefts
in Xenopus laevis: Roles of retinoic acid signaling and
homeobox genes.” Dev Biol 365 (1):229–240. doi: 10.1016/j.
ydbio.2012.02.033.
Khandelwal, K. D., H. van Bokhoven, T. Roscioli, et al. 2013.
“Genomic approaches for studying craniofacial disorders.”
Am J Med Genet C Semin Med Genet 163C (4):218–31. doi:
10.1002/ajmg.c.31379.
Kim, M. S., H. K. Kim, and D. W. Kim. 2020. “Cartilage tissue
engineering for craniofacial reconstruction.” Arch Plast Surg
47 (5):392–403. doi: 10.5999/aps.2020.01095.
Klymkowsky, M. W., C. C. Rossi, and K. B. Artinger. 2010.
“Mechanisms driving neural crest induction and migration in
the zebrafsh and Xenopus laevis.” Cell Adh Migr 4 (4):595–
608. doi: 10.4161/cam.4.4.12962.
Kobayashi, G. S., L. Alvizi, D. Y. Sunaga, et al. 2013. “Susceptibility
to DNA damage as a molecular mechanism for nonsyndromic cleft lip and palate.” PLoS One 8 (6):e65677. doi:
10.1371/journal.pone.0065677.
Kuo, J. S., M. Patel, J. Gamse, et al. 1998. “Opl: A zinc f nger
protein that regulates neural determination and patterning in
Xenopus.” Development 125:2867–82.
LaBonne, C., and M. Bronner-Fraser. 1998. “Induction and patterning of the neural crest, a stem cell-like precursor population.”
Journal of Neurobiology 36 (2):175–89.
Lasser, M., B. Pratt, C. Monahan, et al. 2019. “The many faces of
Xenopus: Xenopus laevis as a model system to study WolfHirschhorn syndrome.” Front Physiol 10:817. doi: 10.3389/
fphys.2019.00817.
Lichtig, H., A. Artamonov, H. Polevoy, et al. 2020. “Modeling
bainbridge-ropers syndrome in Xenopus laevis embryos.”
Front Physiol 11:75. doi: 10.3389/fphys.2020.00075.
Maldonado, E., E. Martinez-Sanz, T. Partearroyo, et al. 2021.
“Maternal folic acid defciency is associated to developing
nasal and palate malformations in mice.” Nutrients 13 (1).
doi: 10.3390/nu13010251.
Mao, J. J., W. V. Giannobile, J. A. Helms, et al. 2007. “Craniofacial
tissue engineering by stem cells.” J Dent Res 85 (11):966–79.
doi: 10.1177/154405910608501101.
Maruyama, T., J. Jeong, T. J. Sheu, et al. 2016. “Stem cells of the
suture mesenchyme in craniofacial bone development, repair
and regeneration.” Nat Commun 7:10526. doi: 10.1038/
ncomms10526.
Meijer, G. J., J. D. de Bruijn, R. Koole, et al. 2007. “Cell-based
bone tissue engineering.” PLoS Medicine 4 (2). doi: doi.
org/10.1371/journal.pmed.0040009.
Merkuri, F., and J. L. Fish. 2019. “Developmental processes regulate craniofacial variation in disease and evolution.” Genesis
57 (1):e23249. doi: 10.1002/dvg.23249.
Meulemans, D., and M. Bronner-Fraser. 2004. “Gene-regulatory
interactions in neural crest evolution and development.” Dev
Cell 7 (3):291–9. doi: 10.1016/j.devcel.2004.08.007.
Mills, A., E. Bearce, R. Cella, et al. 2019. “Wolf-Hirschhorn syndrome-associated genes are enriched in motile neural crest
cells and affect craniofacial development in Xenopus laevis.”
Front Physiol 10:431. doi: 10.3389/fphys.2019.00431.
Moiseiwitsch, J. R. D. 2000. “The role of serotonin and neurotransmitters during craniofacial development.” Crit Rev Oral Biol
Med 11 (2):230–9. doi: 10.1177/10454411000110020601
Monahan, R., K. Seder, P. Patel, et al. 2001. “Hemifacial microsomia: Etiology, diagnosis and treatment.” J Am Dent Assoc
132 (10):1402–8. doi: 10.14219/jada.archive.2001.0055.
Monsoro-Burq, A. H. 2015. “PAX transcription factors in neural
crest development.” Semin Cell Dev Biol 44:87–96. doi:
10.1016/j.semcdb.2015.09.015.
Mork, L., and G. Crump. 2015. “Zebrafsh craniofacial development: A window into early patterning.” Curr Top Dev Biol
115:235–69. doi: 10.1016/bs.ctdb.2015.07.001.
Muggli, E., H. Matthews, A. Penington, et al. 2017. “Association
between prenatal alcohol exposure and craniofacial shape of
children at 12 months of age.” JAMA Pediatr 171 (8):771–80.
doi: 10.1001/jamapediatrics.2017.0778.
Mulligan, M. L., S. K. Felton, A. E. Riek, et al. 2010. “Implications
of vitamin D defciency in pregnancy and lactation.” Am
J Obstet Gynecol 202 (5):429 e1–9. doi: 10.1016/j.ajog.
2009.09.002.
Nagy, L., and J. C. Demke. 2014. “Craniofacial anomalies.” Facial
Plast Surg Clin North Am 22 (4):523–48. doi: 10.1016/j.
fsc.2014.08.002.
Nakano, H., S. Amemiya, K. Shiokawa, et al. 2000. “RNA interference for the organizer-specifc gene Xlim-1 in Xenopus
embryos.” Biochem Biophys Res Commun 274 (2):434–9.
doi: 10.1006/bbrc.2000.3178.
Nakayama, T., M. B. Fish, M. Fisher, et al. 2013. “Simple and
effcient CRISPR/Cas9-mediated targeted mutagenesis in
Xenopus tropicalis.” Genesis 51 (12):835–43. doi: 10.1002/
dvg.22720.
Nutt, S. L., O. J. Bronchain, K. O. Hartley, et al. 2001. “Comparison
of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis.” Genesis
30 (3):110–13. doi: 10.1002/gene.1042.
Obregon, F., C. Vaquette, S. Ivanovski, et al. 2015. “Threedimensional bioprinting for regenerative dentistry and craniofacial tissue engineering.” J Dent Res 94 (9 Suppl):143S–52S.
doi: 10.1177/0022034515588885.
Olesnicky Killian, E. C., D. A. Birkholz, and K. B. Artinger. 2009.
“A role for chemokine signaling in neural crest cell migration
and craniofacial development.” Dev Biol 333 (1):161–72.
doi: 10.1016/j.ydbio.2009.06.031.
Osumi-Yamashita, N., Y. Ninomiya, K. Eto, et al. 1994. “The contribution of both forebrain and midbrain crest cells to the
mesenchyme in the frontonasal mass of mouse embryos.”
Developmental Biology 164:409–19. doi: doi.org/10.1006/
dbio.1994.1211.
Pannia, E., C. E. Cho, R. Kubant, et al. 2016. “Role of maternal
vitamins in programming health and chronic disease.” Nutr
Rev 74 (3):166–80. doi: 10.1093/nutrit/nuv103.
Perez, J. R., D. Kouroupis, D. J. Li, et al. 2018. “Tissue engineering
and cell-based therapies for fractures and bone defects.” Front
Bioeng Biotechnol 6:105. doi: 10.3389/fbioe.2018.00105.
Petrovic, V., P. Zivkovic, D. Petrovic, et al. 2012. “Craniofacial
bone tissue engineering.” Oral Surg Oral Med Oral Pathol
Oral Radiol 114 (3):e1–9. doi: 10.1016/j.oooo.2012.02.030.
Raible, D. W., and J. W. Ragland. 2005. “Reiterated Wnt and BMP
signals in neural crest development.” Semin Cell Dev Biol 16
(6):673–82. doi: 10.1016/j.semcdb.2005.06.008.
Craniofacial Development and Disorders
skeletogenesis highlight ancestral functions in the vertebrate
head.” Development 141 (3):629–38. doi: 10.1242/dev.097261.
Jaskoll, T., G. Abichaker, P. P. Sedghizadeh, et al. 2008.
“Cytomegalovirus induces abnormal chondrogenesis and
osteogenesis during embryonic mandibular development.”
BMC Dev Biol 8:33. doi: 10.1186/1471–213X-8–33.
Johnson, J. M., G. Moonis, G. E. Green, et al. 2011. “Syndromes of
the frst and second branchial arches, part 1: Embryology and
characteristic defects.” AJNR Am J Neuroradiol 32 (1):14–
19. doi: 10.3174/ajnr.A2072.
Kalcheim, C. 2018. “Neural crest emigration: From start to stop.”
Genesis 56 (6–7):e23090. doi: 10.1002/dvg.23090.
Kennedy, A. E., and A. J. Dickinson. 2012. “Median facial clefts
in Xenopus laevis: Roles of retinoic acid signaling and
homeobox genes.” Dev Biol 365 (1):229–240. doi: 10.1016/j.
ydbio.2012.02.033.
Khandelwal, K. D., H. van Bokhoven, T. Roscioli, et al. 2013.
“Genomic approaches for studying craniofacial disorders.”
Am J Med Genet C Semin Med Genet 163C (4):218–31. doi:
10.1002/ajmg.c.31379.
Kim, M. S., H. K. Kim, and D. W. Kim. 2020. “Cartilage tissue
engineering for craniofacial reconstruction.” Arch Plast Surg
47 (5):392–403. doi: 10.5999/aps.2020.01095.
Klymkowsky, M. W., C. C. Rossi, and K. B. Artinger. 2010.
“Mechanisms driving neural crest induction and migration in
the zebrafsh and Xenopus laevis.” Cell Adh Migr 4 (4):595–
608. doi: 10.4161/cam.4.4.12962.
Kobayashi, G. S., L. Alvizi, D. Y. Sunaga, et al. 2013. “Susceptibility
to DNA damage as a molecular mechanism for nonsyndromic cleft lip and palate.” PLoS One 8 (6):e65677. doi:
10.1371/journal.pone.0065677.
Kuo, J. S., M. Patel, J. Gamse, et al. 1998. “Opl: A zinc f nger
protein that regulates neural determination and patterning in
Xenopus.” Development 125:2867–82.
LaBonne, C., and M. Bronner-Fraser. 1998. “Induction and patterning of the neural crest, a stem cell-like precursor population.”
Journal of Neurobiology 36 (2):175–89.
Lasser, M., B. Pratt, C. Monahan, et al. 2019. “The many faces of
Xenopus: Xenopus laevis as a model system to study WolfHirschhorn syndrome.” Front Physiol 10:817. doi: 10.3389/
fphys.2019.00817.
Lichtig, H., A. Artamonov, H. Polevoy, et al. 2020. “Modeling
bainbridge-ropers syndrome in Xenopus laevis embryos.”
Front Physiol 11:75. doi: 10.3389/fphys.2020.00075.
Maldonado, E., E. Martinez-Sanz, T. Partearroyo, et al. 2021.
“Maternal folic acid defciency is associated to developing
nasal and palate malformations in mice.” Nutrients 13 (1).
doi: 10.3390/nu13010251.
Mao, J. J., W. V. Giannobile, J. A. Helms, et al. 2007. “Craniofacial
tissue engineering by stem cells.” J Dent Res 85 (11):966–79.
doi: 10.1177/154405910608501101.
Maruyama, T., J. Jeong, T. J. Sheu, et al. 2016. “Stem cells of the
suture mesenchyme in craniofacial bone development, repair
and regeneration.” Nat Commun 7:10526. doi: 10.1038/
ncomms10526.
Meijer, G. J., J. D. de Bruijn, R. Koole, et al. 2007. “Cell-based
bone tissue engineering.” PLoS Medicine 4 (2). doi: doi.
org/10.1371/journal.pmed.0040009.
Merkuri, F., and J. L. Fish. 2019. “Developmental processes regulate craniofacial variation in disease and evolution.” Genesis
57 (1):e23249. doi: 10.1002/dvg.23249.
Meulemans, D., and M. Bronner-Fraser. 2004. “Gene-regulatory
interactions in neural crest evolution and development.” Dev
Cell 7 (3):291–9. doi: 10.1016/j.devcel.2004.08.007.
Mills, A., E. Bearce, R. Cella, et al. 2019. “Wolf-Hirschhorn syndrome-associated genes are enriched in motile neural crest
cells and affect craniofacial development in Xenopus laevis.”
Front Physiol 10:431. doi: 10.3389/fphys.2019.00431.
Moiseiwitsch, J. R. D. 2000. “The role of serotonin and neurotransmitters during craniofacial development.” Crit Rev Oral Biol
Med 11 (2):230–9. doi: 10.1177/10454411000110020601
Monahan, R., K. Seder, P. Patel, et al. 2001. “Hemifacial microsomia: Etiology, diagnosis and treatment.” J Am Dent Assoc
132 (10):1402–8. doi: 10.14219/jada.archive.2001.0055.
Monsoro-Burq, A. H. 2015. “PAX transcription factors in neural
crest development.” Semin Cell Dev Biol 44:87–96. doi:
10.1016/j.semcdb.2015.09.015.
Mork, L., and G. Crump. 2015. “Zebrafsh craniofacial development: A window into early patterning.” Curr Top Dev Biol
115:235–69. doi: 10.1016/bs.ctdb.2015.07.001.
Muggli, E., H. Matthews, A. Penington, et al. 2017. “Association
between prenatal alcohol exposure and craniofacial shape of
children at 12 months of age.” JAMA Pediatr 171 (8):771–80.
doi: 10.1001/jamapediatrics.2017.0778.
Mulligan, M. L., S. K. Felton, A. E. Riek, et al. 2010. “Implications
of vitamin D defciency in pregnancy and lactation.” Am
J Obstet Gynecol 202 (5):429 e1–9. doi: 10.1016/j.ajog.
2009.09.002.
Nagy, L., and J. C. Demke. 2014. “Craniofacial anomalies.” Facial
Plast Surg Clin North Am 22 (4):523–48. doi: 10.1016/j.
fsc.2014.08.002.
Nakano, H., S. Amemiya, K. Shiokawa, et al. 2000. “RNA interference for the organizer-specifc gene Xlim-1 in Xenopus
embryos.” Biochem Biophys Res Commun 274 (2):434–9.
doi: 10.1006/bbrc.2000.3178.
Nakayama, T., M. B. Fish, M. Fisher, et al. 2013. “Simple and
effcient CRISPR/Cas9-mediated targeted mutagenesis in
Xenopus tropicalis.” Genesis 51 (12):835–43. doi: 10.1002/
dvg.22720.
Nutt, S. L., O. J. Bronchain, K. O. Hartley, et al. 2001. “Comparison
of morpholino based translational inhibition during the development of Xenopus laevis and Xenopus tropicalis.” Genesis
30 (3):110–13. doi: 10.1002/gene.1042.
Obregon, F., C. Vaquette, S. Ivanovski, et al. 2015. “Threedimensional bioprinting for regenerative dentistry and craniofacial tissue engineering.” J Dent Res 94 (9 Suppl):143S–52S.
doi: 10.1177/0022034515588885.
Olesnicky Killian, E. C., D. A. Birkholz, and K. B. Artinger. 2009.
“A role for chemokine signaling in neural crest cell migration
and craniofacial development.” Dev Biol 333 (1):161–72.
doi: 10.1016/j.ydbio.2009.06.031.
Osumi-Yamashita, N., Y. Ninomiya, K. Eto, et al. 1994. “The contribution of both forebrain and midbrain crest cells to the
mesenchyme in the frontonasal mass of mouse embryos.”
Developmental Biology 164:409–19. doi: doi.org/10.1006/
dbio.1994.1211.
Pannia, E., C. E. Cho, R. Kubant, et al. 2016. “Role of maternal
vitamins in programming health and chronic disease.” Nutr
Rev 74 (3):166–80. doi: 10.1093/nutrit/nuv103.
Perez, J. R., D. Kouroupis, D. J. Li, et al. 2018. “Tissue engineering
and cell-based therapies for fractures and bone defects.” Front
Bioeng Biotechnol 6:105. doi: 10.3389/fbioe.2018.00105.
Petrovic, V., P. Zivkovic, D. Petrovic, et al. 2012. “Craniofacial
bone tissue engineering.” Oral Surg Oral Med Oral Pathol
Oral Radiol 114 (3):e1–9. doi: 10.1016/j.oooo.2012.02.030.
Raible, D. W., and J. W. Ragland. 2005. “Reiterated Wnt and BMP
signals in neural crest development.” Semin Cell Dev Biol 16
(6):673–82. doi: 10.1016/j.semcdb.2005.06.008.