S U B J E C T I N D E X
755
Iduronic acid,
estimation of, 363
in mucopolysaccharides, 356-7
from U D P - D - g l u c u r o n i c acid, 377
Imaginal discs (of Drosophila),
trypsin dissociation of, 513
Immunochemistry,
and study of differentiation, 466
Implantation,
of blastocyst, 577, 580
of blastomeres, 579-80
Inducer (see also Inducing Agents),
archencephalic (neuralizing), 545-9
blastopore lip as, 544, 556
cephalic, 540-1
chromatography of, 481
of deuterencephalon, 546-7, 549-50,
552
in gastrulation, 539
inactivation of, 552
lateral half of, 541
mesodermal, 545-8, 550, 552
specific actions of, 545-8, 553
spinal, 546-7, 549-50, 552
trunk, 540
Inducing agents (see also Inducer), 541-3
action o f heat on, 541, 547-51, 556
autoradiography of, 480
bone marrow as, 545-6, 549-50
brain as, 542
chemical nature of, 548-53
chordomesoderm as, 541, 556
combined action of, 546-8
digestion of, 480
D N A as, 553
hexosamine in, 481
m o d e o f action of, 544-5
modification b y chemical agents, 550-1
as modifications of single molecule, 553
proteins as, 543, 549, 551-3
separation of, b y electrophoresis, 481,
552
spinal chord as, 155, 4 8 0 - 1 , 506, 510
tissue extracts as, 542, 544, 552
Inducing power,
discussion of, 541
dorsalization of, 550-1
modification of, by heat, 550
and species-specificity, 540, 5 4 2 - 3 , 556
tested in vitro, 539-40
Induction,
ammonia and, 543, 551
in birds, 555-7
blocked b y cellophane, 480
in cell aggregates, 491, 509-10
and cell permeability, 543
conditions for, 545
in cultures, 478
in ectoderm, 544, 557-8
of enzymes, 264, 307-9, 510
factors in, 481
across filters, 155, 479
gradients of, 547-9
heteroplastic, 540
of lens, 549
of myoblasts, 506
nature of, 468
b y nucleoproteins, 59
primary, in amphibia, 539
Infoldings o f cell surface, 158
Information (between cells),
in exudate trails, 494
Infra-red analysis,
of mucopolysaccharides, 364
Inhibition,
of differentiation, 473, 573
of enzymes, 571
of growth, 257, 572-4, 617
"Inner mass" (mesohyl), 160-1
Inoculum,
size of, 62, 124
Inositol,
as population-dependent
metabolite,
286
requirement for, 116, 123, 2 8 0 - 2
and spreading o f cells, 32
and stability of isolated cells, 63
and strain-L, 289
in synthetic media, 115
Instruments,
for organ culture, 71, 74
Insulin, 593-601
binding of, b y tissues, 595
and bone and cartilage, 597-601
and cell proliferation, 593-5, 600, 635,
649
and corticosteroids, 608, 615
embryo extract and, 598
and fat, 593, 595, 597, 600
and glucokinase reaction, 601
and glucose uptake, 593, 600
and glycogen synthesis, 595, 597, 599,
600
and glycolysis, 2 6 4 - 5 , 267
755
Iduronic acid,
estimation of, 363
in mucopolysaccharides, 356-7
from U D P - D - g l u c u r o n i c acid, 377
Imaginal discs (of Drosophila),
trypsin dissociation of, 513
Immunochemistry,
and study of differentiation, 466
Implantation,
of blastocyst, 577, 580
of blastomeres, 579-80
Inducer (see also Inducing Agents),
archencephalic (neuralizing), 545-9
blastopore lip as, 544, 556
cephalic, 540-1
chromatography of, 481
of deuterencephalon, 546-7, 549-50,
552
in gastrulation, 539
inactivation of, 552
lateral half of, 541
mesodermal, 545-8, 550, 552
specific actions of, 545-8, 553
spinal, 546-7, 549-50, 552
trunk, 540
Inducing agents (see also Inducer), 541-3
action o f heat on, 541, 547-51, 556
autoradiography of, 480
bone marrow as, 545-6, 549-50
brain as, 542
chemical nature of, 548-53
chordomesoderm as, 541, 556
combined action of, 546-8
digestion of, 480
D N A as, 553
hexosamine in, 481
m o d e o f action of, 544-5
modification b y chemical agents, 550-1
as modifications of single molecule, 553
proteins as, 543, 549, 551-3
separation of, b y electrophoresis, 481,
552
spinal chord as, 155, 4 8 0 - 1 , 506, 510
tissue extracts as, 542, 544, 552
Inducing power,
discussion of, 541
dorsalization of, 550-1
modification of, by heat, 550
and species-specificity, 540, 5 4 2 - 3 , 556
tested in vitro, 539-40
Induction,
ammonia and, 543, 551
in birds, 555-7
blocked b y cellophane, 480
in cell aggregates, 491, 509-10
and cell permeability, 543
conditions for, 545
in cultures, 478
in ectoderm, 544, 557-8
of enzymes, 264, 307-9, 510
factors in, 481
across filters, 155, 479
gradients of, 547-9
heteroplastic, 540
of lens, 549
of myoblasts, 506
nature of, 468
b y nucleoproteins, 59
primary, in amphibia, 539
Infoldings o f cell surface, 158
Information (between cells),
in exudate trails, 494
Infra-red analysis,
of mucopolysaccharides, 364
Inhibition,
of differentiation, 473, 573
of enzymes, 571
of growth, 257, 572-4, 617
"Inner mass" (mesohyl), 160-1
Inoculum,
size of, 62, 124
Inositol,
as population-dependent
metabolite,
286
requirement for, 116, 123, 2 8 0 - 2
and spreading o f cells, 32
and stability of isolated cells, 63
and strain-L, 289
in synthetic media, 115
Instruments,
for organ culture, 71, 74
Insulin, 593-601
binding of, b y tissues, 595
and bone and cartilage, 597-601
and cell proliferation, 593-5, 600, 635,
649
and corticosteroids, 608, 615
embryo extract and, 598
and fat, 593, 595, 597, 600
and glucokinase reaction, 601
and glucose uptake, 593, 600
and glycogen synthesis, 595, 597, 599,
600
and glycolysis, 2 6 4 - 5 , 267