756
S U B J E C T I N D E X
Insulin—Continued
and growth, 264, 593
and growth hormone, 595, 6 0 0 - 1 , 615
labelled, 595
lipid phosphorus and, 593, 608
and malignant cells, 267, 5 9 3 - 4
and mammary function, 127, 635-8
and mucopolysaccharides, 385
and muscle development, 128
and nicotinamide, 600
pinocytosis and, 264-5
and protein synthesis, 593
R N A and, 593, 600, 608
in synthetic media, 102, 117, 128
Insulinase, 598
Interactions,
substrate and, between cells, 493
between tissues, and differentiation,
469, 478, 491, 495
Intercellular connexions,
contractions of, 492
Interconversions,
of cell types in vivo and in vitro, 473
Interference microscope,
hanging-drop cultures and, 33
and measurement of protein content, 331
and nuclear changes, 220
Intermitotic period (see also Cell cycle,
Interphase), 220, 335
Internal environment, 10
Internal marginal zone,
of embryo, 533, 537-9
Interphase,
chromocenter in, 431
chromosome activity in, 439
definition of, 415
D N A synthesis in, 324, 334-5, 338, 416
dry-mass increase in, 334-5, 338-40
R N A synthesis in, 330, 334-5, 338
salivary gland chromosomes and, 439
sex chromatin in, 434
time-lapse photography and, 332
variation in, 422
Intersexes, 408, 451, 581
Intestinal cells,
anaerobic protein synthesis by, 251
behaviour in aggregates, 522
connective tissue and differentiation of,
538
as epitheliocytes, 146
and j3-galactosidase, 264
respiration of, 252
sources o f carbohydrate for, 245-6
turnover time of, 294
Intestine,
regions of gastrula producing, 537, 539
Inversion,
in chromosomes, 441, 442
Iodide,
and proteolytic enzymes, 603
and thyrotrophic hormone, 603
Iodine,
and activity o f antithyroid agents, 644
uptake of radioactive, 642
Iodoacetamide, 253
Iodoacetate, 225, 253, 571
Ion-exchange resins,
chromatography on, 304, 361, 365
use of, 22
Ionic environment,
and age o f tissue, 108
altered b y glass, 32-3
and cell surface, 33, 150, 520
different for different cells, 108
for dissociated cells, 63
and form of Naegleria, 166
minimal, 111
and mucopolysaccharides, 357
and osmotic environment, 23
Ionic equilibrium (Electrolyte balance),
of blastula, 159
at the cell surface, 108
C 0 2 and, 25
dissociating agents and, 58
fibroblasts, macrophages and, 167
hormones and, 167
of Naegleria, 166
of saline solutions, 100
in tissue cultures, 2 6 - 7
Ionic pumps, 28, 83
Ion transport (see also Ionic pumps),
mucopolysaccharides and, 357, 376
Iris epithelium,
sex hormones and, 616
Iron,
requirement for, 111-12, 282
Iso-affinities,
between cells, 522
Isoleucine,
in Eagle's medium, 280
and heart tissue, 299-300
and kidney, 303
and liver, 303
and L-strain, 114
S U B J E C T I N D E X
Insulin—Continued
and growth, 264, 593
and growth hormone, 595, 6 0 0 - 1 , 615
labelled, 595
lipid phosphorus and, 593, 608
and malignant cells, 267, 5 9 3 - 4
and mammary function, 127, 635-8
and mucopolysaccharides, 385
and muscle development, 128
and nicotinamide, 600
pinocytosis and, 264-5
and protein synthesis, 593
R N A and, 593, 600, 608
in synthetic media, 102, 117, 128
Insulinase, 598
Interactions,
substrate and, between cells, 493
between tissues, and differentiation,
469, 478, 491, 495
Intercellular connexions,
contractions of, 492
Interconversions,
of cell types in vivo and in vitro, 473
Interference microscope,
hanging-drop cultures and, 33
and measurement of protein content, 331
and nuclear changes, 220
Intermitotic period (see also Cell cycle,
Interphase), 220, 335
Internal environment, 10
Internal marginal zone,
of embryo, 533, 537-9
Interphase,
chromocenter in, 431
chromosome activity in, 439
definition of, 415
D N A synthesis in, 324, 334-5, 338, 416
dry-mass increase in, 334-5, 338-40
R N A synthesis in, 330, 334-5, 338
salivary gland chromosomes and, 439
sex chromatin in, 434
time-lapse photography and, 332
variation in, 422
Intersexes, 408, 451, 581
Intestinal cells,
anaerobic protein synthesis by, 251
behaviour in aggregates, 522
connective tissue and differentiation of,
538
as epitheliocytes, 146
and j3-galactosidase, 264
respiration of, 252
sources o f carbohydrate for, 245-6
turnover time of, 294
Intestine,
regions of gastrula producing, 537, 539
Inversion,
in chromosomes, 441, 442
Iodide,
and proteolytic enzymes, 603
and thyrotrophic hormone, 603
Iodine,
and activity o f antithyroid agents, 644
uptake of radioactive, 642
Iodoacetamide, 253
Iodoacetate, 225, 253, 571
Ion-exchange resins,
chromatography on, 304, 361, 365
use of, 22
Ionic environment,
and age o f tissue, 108
altered b y glass, 32-3
and cell surface, 33, 150, 520
different for different cells, 108
for dissociated cells, 63
and form of Naegleria, 166
minimal, 111
and mucopolysaccharides, 357
and osmotic environment, 23
Ionic equilibrium (Electrolyte balance),
of blastula, 159
at the cell surface, 108
C 0 2 and, 25
dissociating agents and, 58
fibroblasts, macrophages and, 167
hormones and, 167
of Naegleria, 166
of saline solutions, 100
in tissue cultures, 2 6 - 7
Ionic pumps, 28, 83
Ion transport (see also Ionic pumps),
mucopolysaccharides and, 357, 376
Iris epithelium,
sex hormones and, 616
Iron,
requirement for, 111-12, 282
Iso-affinities,
between cells, 522
Isoleucine,
in Eagle's medium, 280
and heart tissue, 299-300
and kidney, 303
and liver, 303
and L-strain, 114
