Bioprocess and algae reactor technology, apoptosis

Following a général overview of antibiotics spectinomycin is discussed in some détail, including methods of production and analysis. Results of the expérimental optimization of glucose feed concentration and analysis of the results are presented. The mechanism of spectinomycin biosynthesis is described by a model employing an exponential structure. We show conclusively that biosynthesis dépends on the allocation of glucose and oxygen resource by the microorganism and that yield can be controlled by manipulating these two variables. Finally, nonlinear Systems theory is applied to predict the concentration from air flow rate values. A control strategy for optimal spectinomycin production is also presented.