Table 10.1
(continued)
Associated
compound or diet
type
Modulated genes
Function
Model
Cancer type
Reference
Erucin
P21:
ERK1/2:
Proliferation
In vitro (cell culture)
Prostate
Melchini et al. (2013)
Curcumin
EGF pathway;
Proliferation/survival
In vitro (cell culture)
Breast
Cine et al. (2013)
Non-digestible
fraction common
beans
P53 pathway
Apoptosis, cell cycle
arrest and cell cycle
proliferation
In vitro (cell culture)
Colon
Campos-Vega et al.
(2010)
Associated compound or
diet type
Modulated genes
Function
Model
Reference
Diabetes
Cocoa phenolic extract
PI3, pathway
Survival
In vitro (cells)
Lin et al. (2012)
Ginsenoside
Bax
Fas
Caspase-3
Apoptosis
In vitro (cell culture)
Chen et al. (2012)
High-fat diet
Cacna1d, Chd2
Clip2, Igf2bp2, Dach1,
Tspan8
Cdkn1b, Tmem27, Pax6,
Cat, Prdx4
and Txnip
Increased cell cycle
progression,
proliferation and
differentiation of islet
cells, and oxidative
stress
In vivo (rats)
Dreja et al. (2010)
Acacia polyphenols
Adiponectin:
TNF-a ;
Glut-4:
Body weight and
glucose output
In vivo (mice)
Ikarashi et al. (2011)
Caffeic acid
Glk:
Pyk:
Hepatic glucose output
In vivo (Rats)
Celik et al. (2009)
Ginkgo biloba extract
GLUT4:
Glucose transporters
In vivo (rats)
Li et al. (2010)
eNOS
eNOS:
Nitric oxide synthase
In vivo (rats)
Wang et al. (2009)
Quercetin
Cdkn1a;
Cell cycle regulation
In vivo (rats)
Kobori et al. (2009)
(continued)
300
R. Campos-Vega et al.