120
C. Picot et al.
Table 10.4
Chronic dietary intakes of domoic acid, okadaic acid and spirolide obtained by a probabilistic approach and comparison with toxicological
reference values for harvested, purchased and all bivalves
DA
OA
SPX
Exposure* (g/kg
bw/day) Exposure* (ng/kg
bw/day)
Exposure* (ng/kg
bw/day)
Censored values treatment
Bivalve source
Mean Median
P95
Mean Median
P95
Mean Median P95
T1 (SPX) or T2a (DA and OA) Harvested bivalves
0.07
0.05
0.18
44:4
29.3
134
3.5
2.8
8:3
Purchased bivalves 0.04
0.03
0.13
9:70
5.10
34:5 1.9
1.3
5:70
All bivalves
0.11
0.09
0.26
54:1
39.0
149
5.4
4.60
11:9
T2b
Harvested bivalves
0.07
0.05
0.20
45:9
30.9
137
Purchased bivalves 0.04
0.03
0.14
10:3
5.40
36:6
All bivalves
0.11
0.09
0.28
56:2
41.1
155
Tolerable daily intake
No tolerable daily intake allocated
ARfD
100
a
/30
b
333
a
/300
b
No ARfD allocated
ARfD
acute reference dose
*Assuming a body weight of 60 kg
a
JECFA
Joint FAO/WHO Expert Committee on Food Additives
b
EFSA
European Food Safety Authority