703
Table 14.3 Methods of administering some commonly used antimicrobial compounds to fi sh
Antimicrobial
compound
Diseases controlled
Method(s) of administration
Acrifl avine, neutral
Columnaris
5–10 mg/l in water for
several hours to several days
Amoxicillin
Furunculosis, gill disease
60–80 mg/kg body weight of
fi sh/day/10 days
Benzalkonium
chloride
Fin rot, gill disease
1–2 mg/l of water for 1 h,
100 mg/l of water for 2 min
Chloramine B or T
Fin rot, gill disease mycobacteriosis
18–20 mg/l of water at
pH 7.5–8.0, treat for
2–3 days
Enrofl oxacin
(=Baytril)
BKD, furunculosis
10 or 20 mg/kg body weight/
day/for 10 days
Erythromycin
BKD, streptococcicosis
25–100 mg/kg of fi sh/day for
4–21 days
20 mg of erythromycin/kg of
broodstock as an injection
Florfenicol
Furunculosis, vibriosis
10 mg/kg body weight of
fi sh/day for 10 days
Flumequine
Furunculosis, ERM, vibriosis
6 mg/kg of fi sh/day for
6 days
Furanace
Coldwater disease, columnaris, fi n rot,
gill disease, haemorrhagic septicaemia,
vibriosis
(a) 2–4 mg/kg of fi sh/day for
3–5 days
(b) 0.5–1 mg/l of water for
5–10 min, as a bath
Iodophors
Acinetobacter disease, BKD,
fl avobacteriosis, furunculosis,
haemorrhagic septicaemia,
mycobacteriosis
50–200 mg of available
iodine/l of water for
10–15 min
Oxolinic acid
Columnaris, ERM, furunculosis,
haemorrhagic septicaemia, vibriosis
(a) 10 mg/kg of fi sh/day for
10 days
(b) 1 mg/l of water, as a bath
for 24 h (recommended for
columnaris)
Oxytetracycline
Acinetobacter disease, CE, coldwater
disease, columnaris, edwardsiellosis,
emphysematous putrefactive disease,
ERM, enteric septicaemia, fi n rot,
furunculosis, gill disease, haemorrhagic
septicaemia, redpest, salmonid blood
spot, saltwater columnaris,
streptococcicosis, ulcer disease
50–75 mg/kg of fi sh/day for
10 days (doses of 300 mg/kg
of fi sh/day for indefi nite
periods are used to treat
RTFS)
Potentiated
sulphonamide
ERM, furunculosis, haemorrhagic
septicaemia, vibriosis
30 mg/kg of fi sh/day for
10 days
Sodium
nifurstyrenate
Streptococcicosis
50 mg/kg of fi sh/day for
3–5 days
Farmed Fish
Table 14.3 Methods of administering some commonly used antimicrobial compounds to fi sh
Antimicrobial
compound
Diseases controlled
Method(s) of administration
Acrifl avine, neutral
Columnaris
5–10 mg/l in water for
several hours to several days
Amoxicillin
Furunculosis, gill disease
60–80 mg/kg body weight of
fi sh/day/10 days
Benzalkonium
chloride
Fin rot, gill disease
1–2 mg/l of water for 1 h,
100 mg/l of water for 2 min
Chloramine B or T
Fin rot, gill disease mycobacteriosis
18–20 mg/l of water at
pH 7.5–8.0, treat for
2–3 days
Enrofl oxacin
(=Baytril)
BKD, furunculosis
10 or 20 mg/kg body weight/
day/for 10 days
Erythromycin
BKD, streptococcicosis
25–100 mg/kg of fi sh/day for
4–21 days
20 mg of erythromycin/kg of
broodstock as an injection
Florfenicol
Furunculosis, vibriosis
10 mg/kg body weight of
fi sh/day for 10 days
Flumequine
Furunculosis, ERM, vibriosis
6 mg/kg of fi sh/day for
6 days
Furanace
Coldwater disease, columnaris, fi n rot,
gill disease, haemorrhagic septicaemia,
vibriosis
(a) 2–4 mg/kg of fi sh/day for
3–5 days
(b) 0.5–1 mg/l of water for
5–10 min, as a bath
Iodophors
Acinetobacter disease, BKD,
fl avobacteriosis, furunculosis,
haemorrhagic septicaemia,
mycobacteriosis
50–200 mg of available
iodine/l of water for
10–15 min
Oxolinic acid
Columnaris, ERM, furunculosis,
haemorrhagic septicaemia, vibriosis
(a) 10 mg/kg of fi sh/day for
10 days
(b) 1 mg/l of water, as a bath
for 24 h (recommended for
columnaris)
Oxytetracycline
Acinetobacter disease, CE, coldwater
disease, columnaris, edwardsiellosis,
emphysematous putrefactive disease,
ERM, enteric septicaemia, fi n rot,
furunculosis, gill disease, haemorrhagic
septicaemia, redpest, salmonid blood
spot, saltwater columnaris,
streptococcicosis, ulcer disease
50–75 mg/kg of fi sh/day for
10 days (doses of 300 mg/kg
of fi sh/day for indefi nite
periods are used to treat
RTFS)
Potentiated
sulphonamide
ERM, furunculosis, haemorrhagic
septicaemia, vibriosis
30 mg/kg of fi sh/day for
10 days
Sodium
nifurstyrenate
Streptococcicosis
50 mg/kg of fi sh/day for
3–5 days
Farmed Fish