St Pierre T, Tran KC, Webb J, Macey DJ, Heywood BR, Sparks NH, Wade VJ, Mann S,
Pootrakul P (1991) Organ-specific crystalline strcutures of ferritin cores in beta-thalassemia/
hemoglobin E. Biol Met 4:162–165
Stiles AR, McDonald JG, Bauman DR, Russell DW (2009) CYP7B1: one cytochrome P450, two
human genetic diseases, and multiple physiological functions. J Biol Chem 284:28485–28489
Stillman TJ, Connolly PP, Latimer CL, Morland AF, Quail MA, Andrews SC, Treffry A, Guest JR,
Artymiuk PJ, Harrison PM (2003) Insights into the effects on metal binding of the systematic
substitution of five key glutamate ligands in the ferritin of Escherichia coli. J Biol Chem
278:26275–26286
Su M, Cavallo S, Stefanini S, Chiancone E, Chasteen ND (2005) The so-called Listeria innocua
ferritin is a Dps protein. Iron incorporation, detoxification, and DNA protection properties,
Biochemistry 44:5572–5578
Takagi H, Shi D, Ha Y, Allewell NM, Theil EC (1998) Localized unfolding at the junction of three
ferritin subunits; A mechanism for iron release? J Biol Chem J Biol Chem 273:18685–18688
Theil EC (1987) Ferritin: structure, gene regulation, and cellular function in animals, plants, and
microorganisms. Annu Rev Biochem 56:289–315
Theil EC, Goss DJ (2009) Living with iron (and oxygen): questions and answers about iron
homeostasis. Chem Rev 109:4568–4579
Theil EC, Liu XS, Tosha T (2008) Gated pores in the ferritin protein nanocage, Inorg Chim Acta
361:868–874
Tosha T, Hasan MR, Theil EC (2008) The ferritin Fe2 site at the diiron catalytic center controls
the reaction with O 2 in the rapid mineralization pathway. Proc Natl Acad Sci USA
105:18182–18187
Toussaint L, Bertrand L, Hue L, Crichton RR, Declercq JP (2007) High-resolution X-ray
structures of human apoferritin H-chain mutants correlated with their activity and metalbinding sites. J Mol Biol 365:440–452
Treffry A, Zhao Z, Quail MA, Guest JR, Harrison PM (1998) How the presence of three iron
binding sites affects the iron storage function of the ferritin (EcFtnA) of Escherichia coli.
FEBS Lett 432:213–218
Trikha J, Theil EC, Allewell NM (1995) High resolution crystal structures of amphibian red-cell L
ferritin: potential roles for structural plasticity and solvation in function. J Mol Biol
248:949–967
Turano P, Lalli D, Felli I, Theil E, Bertini I (2010) NMR reveals pathway for ferric mineral
precursors to the central cavity of ferritin. Proc Natl Acad Sci USA 107:545–550
Wade VJ, Treffry A, Laulhere J-P, Bauminger ER, Cleton MI, Mann S, Briat J-F, Harrison PM
(1993) Structure and composition of ferritin cores from pea seed (Pisum sativum). Biochim
Biophys Acta 1161:91–96
Waldo GS, Wright E, Whang ZH, Briat JF, Theil EC, Sayers DE (1995) Formation of the ferritin
iron mineral occurs in plastids. Plant Physiol 109:797–802
Yamashita M, Ojima N, Sakamoto T (1996) Molecular cloning and cold-inducible gene expression of ferritin H subunit isoforms in rainbow trout cells. J Biol Chem 271:26908–26913
2 Maxi- and Mini-Ferritins: Minerals and Protein Nanocages
47
Pootrakul P (1991) Organ-specific crystalline strcutures of ferritin cores in beta-thalassemia/
hemoglobin E. Biol Met 4:162–165
Stiles AR, McDonald JG, Bauman DR, Russell DW (2009) CYP7B1: one cytochrome P450, two
human genetic diseases, and multiple physiological functions. J Biol Chem 284:28485–28489
Stillman TJ, Connolly PP, Latimer CL, Morland AF, Quail MA, Andrews SC, Treffry A, Guest JR,
Artymiuk PJ, Harrison PM (2003) Insights into the effects on metal binding of the systematic
substitution of five key glutamate ligands in the ferritin of Escherichia coli. J Biol Chem
278:26275–26286
Su M, Cavallo S, Stefanini S, Chiancone E, Chasteen ND (2005) The so-called Listeria innocua
ferritin is a Dps protein. Iron incorporation, detoxification, and DNA protection properties,
Biochemistry 44:5572–5578
Takagi H, Shi D, Ha Y, Allewell NM, Theil EC (1998) Localized unfolding at the junction of three
ferritin subunits; A mechanism for iron release? J Biol Chem J Biol Chem 273:18685–18688
Theil EC (1987) Ferritin: structure, gene regulation, and cellular function in animals, plants, and
microorganisms. Annu Rev Biochem 56:289–315
Theil EC, Goss DJ (2009) Living with iron (and oxygen): questions and answers about iron
homeostasis. Chem Rev 109:4568–4579
Theil EC, Liu XS, Tosha T (2008) Gated pores in the ferritin protein nanocage, Inorg Chim Acta
361:868–874
Tosha T, Hasan MR, Theil EC (2008) The ferritin Fe2 site at the diiron catalytic center controls
the reaction with O 2 in the rapid mineralization pathway. Proc Natl Acad Sci USA
105:18182–18187
Toussaint L, Bertrand L, Hue L, Crichton RR, Declercq JP (2007) High-resolution X-ray
structures of human apoferritin H-chain mutants correlated with their activity and metalbinding sites. J Mol Biol 365:440–452
Treffry A, Zhao Z, Quail MA, Guest JR, Harrison PM (1998) How the presence of three iron
binding sites affects the iron storage function of the ferritin (EcFtnA) of Escherichia coli.
FEBS Lett 432:213–218
Trikha J, Theil EC, Allewell NM (1995) High resolution crystal structures of amphibian red-cell L
ferritin: potential roles for structural plasticity and solvation in function. J Mol Biol
248:949–967
Turano P, Lalli D, Felli I, Theil E, Bertini I (2010) NMR reveals pathway for ferric mineral
precursors to the central cavity of ferritin. Proc Natl Acad Sci USA 107:545–550
Wade VJ, Treffry A, Laulhere J-P, Bauminger ER, Cleton MI, Mann S, Briat J-F, Harrison PM
(1993) Structure and composition of ferritin cores from pea seed (Pisum sativum). Biochim
Biophys Acta 1161:91–96
Waldo GS, Wright E, Whang ZH, Briat JF, Theil EC, Sayers DE (1995) Formation of the ferritin
iron mineral occurs in plastids. Plant Physiol 109:797–802
Yamashita M, Ojima N, Sakamoto T (1996) Molecular cloning and cold-inducible gene expression of ferritin H subunit isoforms in rainbow trout cells. J Biol Chem 271:26908–26913
2 Maxi- and Mini-Ferritins: Minerals and Protein Nanocages
47