Oaki Y, Imai H (2005) The hierarchical architecture of nacre and its mimetic material. Angew
Chem Int Ed Engl 44:6571–6575
Patthy L (1999) Genome evolution and the evolution of exon-shuffling – a review. Gene
238:103–114
Pereira-Mouries L, Almeida MJ, Ribeiro C, Peduzzi J, Barthelemy M, Milet C, Lopez E (2002)
Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima. Eur J
Biochem 269:4994–5003
Rousseau M, Lopez E, Coute A, Mascarel G, Smith DC, Naslain R, Bourrat X (2005a) Sheet nacre
growth mechanism: a Voronoi model. J Struct Biol 149:149–157
Rousseau M, Lopez E, Stempfle P, Brendle M, Franke L, Guette A, Naslain R, Bourrat X (2005b)
Multiscale structure of sheet nacre. Biomaterials 26:6254–6262
Samata T (1990) Ca-binding glycoproteins in molluscan shells with different types of ultrastructure. Veliger 33:190–201
Samata T (2004) Recent advances in studies on nacreous layer biomineralization: molecular and
cellular aspects. Thalassas 20:25–44
Samata T, Hayashi N, Kono M, Hasegawa K, Horita C, Akera S (1999) A new matrix protein
family related to the nacreous layer formation of Pinctada fucata. FEBS Lett 462:225–229
Sarikaya M, Aksay I (1992) Nacre of abalone shell: a natural multifunctional nanolaminated
ceramic-polymer composite material. In: Case ST (ed) Results and problems in cell differentiation, vol 19. Springer, Berlin/London, pp 1–25
Saruwatari K, Matsui T, Mukai H, Nagasawa H, Kogure T (2009) Nucleation and growth of
aragonite crystals at the growth front of nacres in pearl oyster, Pinctada fucata. Biomaterials
30:3028–3034
Schaffer TE, IonescuZanetti C, Proksch R, Fritz M, Walters DA, Almqvist N, Zaremba CM,
Belcher AM, Smith BL, Stucky GD, Morse DE, Hansma PK (1997) Does abalone nacre form
by heteroepitaxial nucleation or by growth through mineral bridges? Chem Mater 9:1731–1740
Schonitzer V, Weiss IM (2007) The structure of mollusc larval shells formed in the presence of the
chitin synthase inhibitor Nikkomycin Z. BMC Struct Biol 7:71
Shen XY, Belcher AM, Hansma PK, Stucky GD, Morse DE (1997) Molecular cloning and
characterization of lustrin A, a matrix protein from shell and pearl nacre of Haliotis rufescens.
J Biol Chem 272:32472–32481
Simkiss K, Wilbur KM (1989) Biomineralization: cell biology and mineral deposition. Academic,
San Diego, pp 230–250
Song F, Zhang XH, Bai YL (2002) Microstructure and characteristics in the organic matrix layers
of nacre. J Mater Res 17:1567–1570
Sudo S, Fujikawa T, Nagakura T, Ohkubo T, Sakaguchi K, Tanaka M, Nakashima K, Takahashi T
(1997) Structures of mollusc shell framework proteins. Nature 387:563–564
Suzuki M, Sakuda S, Nagasawa H (2007) Identification of chitin in the prismatic layer of the shell
and a chitin synthase gene from the Japanese pearl oyster, Pinctada fucata. Biosci Biotech
Biochem 71:1735–1744
Suzuki M, Saruwatari K, Kogure T, Yamamoto Y, Nishimura T, Kato T, Nagasawa H (2009) An
acidic matrix protein, Pif, is a key macromolecule for nacre formation. Science 325:1388–1390
Takakura D, Norizuki M, Ishikawa F, Samata T (2008) Isolation and characterization of the Nlinked oligosaccharides in nacrein from Pinctada fucata. Mar Biotechnol 10:290–296
Takeuchi T, Endo K (2006) Biphasic and dually coordinated expression of the genes encoding
major shell matrix proteins in the pearl oyster Pinctada fucata. Mar Biotechnol 8:52–61
Treccani L, Mann K, Heinemann F, Fritz M (2006) Perlwapin, an abalone nacre protein with three
four-disulfide core (whey acidic protein) domains, inhibits the growth of calcium carbonate
crystals. Biophys J 91(7):2601–2608
Wang N, Kinoshita S, Riho C, Maeyama K, Nagai K, Watabe S (2009) Quantitative expression
analysis of nacreous shell matrix protein genes in the process of pearl biogenesis. Comp
Biochem Phys B 154:346–350
12 Molecular Approaches to Understand Biomineralization of Shell Nacreous Layer
351
Chem Int Ed Engl 44:6571–6575
Patthy L (1999) Genome evolution and the evolution of exon-shuffling – a review. Gene
238:103–114
Pereira-Mouries L, Almeida MJ, Ribeiro C, Peduzzi J, Barthelemy M, Milet C, Lopez E (2002)
Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima. Eur J
Biochem 269:4994–5003
Rousseau M, Lopez E, Coute A, Mascarel G, Smith DC, Naslain R, Bourrat X (2005a) Sheet nacre
growth mechanism: a Voronoi model. J Struct Biol 149:149–157
Rousseau M, Lopez E, Stempfle P, Brendle M, Franke L, Guette A, Naslain R, Bourrat X (2005b)
Multiscale structure of sheet nacre. Biomaterials 26:6254–6262
Samata T (1990) Ca-binding glycoproteins in molluscan shells with different types of ultrastructure. Veliger 33:190–201
Samata T (2004) Recent advances in studies on nacreous layer biomineralization: molecular and
cellular aspects. Thalassas 20:25–44
Samata T, Hayashi N, Kono M, Hasegawa K, Horita C, Akera S (1999) A new matrix protein
family related to the nacreous layer formation of Pinctada fucata. FEBS Lett 462:225–229
Sarikaya M, Aksay I (1992) Nacre of abalone shell: a natural multifunctional nanolaminated
ceramic-polymer composite material. In: Case ST (ed) Results and problems in cell differentiation, vol 19. Springer, Berlin/London, pp 1–25
Saruwatari K, Matsui T, Mukai H, Nagasawa H, Kogure T (2009) Nucleation and growth of
aragonite crystals at the growth front of nacres in pearl oyster, Pinctada fucata. Biomaterials
30:3028–3034
Schaffer TE, IonescuZanetti C, Proksch R, Fritz M, Walters DA, Almqvist N, Zaremba CM,
Belcher AM, Smith BL, Stucky GD, Morse DE, Hansma PK (1997) Does abalone nacre form
by heteroepitaxial nucleation or by growth through mineral bridges? Chem Mater 9:1731–1740
Schonitzer V, Weiss IM (2007) The structure of mollusc larval shells formed in the presence of the
chitin synthase inhibitor Nikkomycin Z. BMC Struct Biol 7:71
Shen XY, Belcher AM, Hansma PK, Stucky GD, Morse DE (1997) Molecular cloning and
characterization of lustrin A, a matrix protein from shell and pearl nacre of Haliotis rufescens.
J Biol Chem 272:32472–32481
Simkiss K, Wilbur KM (1989) Biomineralization: cell biology and mineral deposition. Academic,
San Diego, pp 230–250
Song F, Zhang XH, Bai YL (2002) Microstructure and characteristics in the organic matrix layers
of nacre. J Mater Res 17:1567–1570
Sudo S, Fujikawa T, Nagakura T, Ohkubo T, Sakaguchi K, Tanaka M, Nakashima K, Takahashi T
(1997) Structures of mollusc shell framework proteins. Nature 387:563–564
Suzuki M, Sakuda S, Nagasawa H (2007) Identification of chitin in the prismatic layer of the shell
and a chitin synthase gene from the Japanese pearl oyster, Pinctada fucata. Biosci Biotech
Biochem 71:1735–1744
Suzuki M, Saruwatari K, Kogure T, Yamamoto Y, Nishimura T, Kato T, Nagasawa H (2009) An
acidic matrix protein, Pif, is a key macromolecule for nacre formation. Science 325:1388–1390
Takakura D, Norizuki M, Ishikawa F, Samata T (2008) Isolation and characterization of the Nlinked oligosaccharides in nacrein from Pinctada fucata. Mar Biotechnol 10:290–296
Takeuchi T, Endo K (2006) Biphasic and dually coordinated expression of the genes encoding
major shell matrix proteins in the pearl oyster Pinctada fucata. Mar Biotechnol 8:52–61
Treccani L, Mann K, Heinemann F, Fritz M (2006) Perlwapin, an abalone nacre protein with three
four-disulfide core (whey acidic protein) domains, inhibits the growth of calcium carbonate
crystals. Biophys J 91(7):2601–2608
Wang N, Kinoshita S, Riho C, Maeyama K, Nagai K, Watabe S (2009) Quantitative expression
analysis of nacreous shell matrix protein genes in the process of pearl biogenesis. Comp
Biochem Phys B 154:346–350
12 Molecular Approaches to Understand Biomineralization of Shell Nacreous Layer
351