Levi-Kalisman Y, Falini G, Addadi L, Weiner S (2001) Structure of the nacreous organic matrix of
a bivalve mollusk shell examined in the hydrated state using Cryo-TEM. J Struct Biol
135:8–17
Lin AYM, Chen PY, Meyers MA (2008) The growth of nacre in the abalone shell. Acta Biomater
4:131–138
Lowenstam HA, Weiner S (1989) On biomineralization. Oxford University Press, New York/
Oxford, pp 99–110
Ma ZJ, Huang J, Sun J, Wang GN, Li CZ, Xie LP, Zhang RQ (2007) A novel extrapallial fluid
protein controls the morphology of nacre lamellae in the pearl oyster, Pinctada fucata. J Biol
Chem 282:23253–23263
Mann S (1993) Molecular tectonics in biomineralization and biomimetic materials chemistry.
Nature 365:499–505
Mann S (2001) Biomineralization: principles and concepts in bioinorganic materials chemistry.
Oxford University Press, Oxford, pp 8, 78, 103–106
Mann K, Weiss IM, Andre S, Gabius HJ, Fritz M (2000) The amino-acid sequence of the abalone
(Haliotis laevigata) nacre protein perlucin – Detection of a functional C-type lectin domain
with galactose/mannose specificity. Eur J Biochem 267:5257–5264
Mann K, Siedler F, Treccani L, Heinemann F, Fritz M (2007) Perlinhibin, a cysteine-, histidine-,
and arginine-rich miniprotein from abalone (Haliotis laevigata) nacre, inhibits in vitro calcium
carbonate crystallization. Biophys J 93:1246–1254
Marin F, Luquet G (2004) Molluscan shell proteins. CR Palevol 3:469–492
Marin F, Luquet G, Marie B, Medakovic D (2008) Molluscan shell proteins: primary structure,
origin, and evolution. Curr Top Dev Biol 80:209–276
Matsushiro A, Miyashita T, Miyamoto H, Morimoto K, Tonomura B, Tanaka A, Sato K (2003)
Presence of protein complex is prerequisite for aragonite crystallization in the nacreous layer.
Mar Biotechnol 5:37–44
Meyers MA, Lin AYM, Chen PY, Muyco J (2008) Mechanical strength of abalone nacre: role of
the soft organic layer. J Mech Behav Biomed 1:76–85
Michenfelder M, Fu G, Lawrence C, Weaver JC, Wustman BA, Taranto L, Evans JS, Morse DE
(2003) Characterization of two molluscan crystal-modulating biomineralization proteins and
identification of putative mineral binding domains. Biopolymers 70:522–533
Miyamoto H, Miyashita T, Okushima M, Nakano S, Morita T, Matsushiro A (1996) A carbonic
anhydrase from the nacreous layer in oyster pearls. Proc Natl Acad Sci USA 93:9657–9660
Miyamoto H, Miyoshi F, Kohno J (2005) The carbonic anhydrase domain protein nacrein is
expressed in the epithelial cells of the mantle and acts as a negative regulator in calcification in
the mollusc Pinctada fucata. Zool Sci 22:311–315
Miyashita T, Takagi R, Okushima M, Nakano S, Miyamoto H, Nishikawa E, Matsushiro A (2000)
Complementary DNA cloning and characterization of pearlin, a new class of matrix protein in
the nacreous layer of oyster pearls. Mar Biotechnol 2:409–418
Miyazaki Y, Nishida T, Aoki H, Samata T (2010) Expression of genes responsible for biomineralization of Pinctada fucata during development. Comp Biochem Phys B 155:241–248
Nakahara H (1981) The Formation and Fine Structure of the Organic Phase of the Nacreous Layer
in Mollusc Shell. In: Mollusk Research (Collection of Assays Contributed in Celebration of
Professor Masae Omori’s 60th Birthday), pp 21–27
Nudelman F, Gotliv BA, Addadi L, Weiner S (2006) Mollusk shell formation: mapping the
distribution of organic matrix components underlying a single aragonitic tablet in nacre.
J Struct Biol 153:176–187
Nudelman F, Chen HH, Goldberg HA, Weiner S, Addadi L (2007) Spiers memorial lecture:
lessons from biomineralization: comparing the growth strategies of mollusc shell prismatic and
nacreous layers in Atrina rigida. Faraday Discuss 136:9–25
Nudelman F, Shimoni E, Klein E, Rousseau M, Bourrat X, Lopez E, Addadi L, Weiner S (2008)
Forming nacreous layer of the shells of the bivalves Atrina rigida and Pinctada margaritifera:
an environmental- and cryo-scanning electron microscopy study. J Struct Biol 162:290–300
350
L.-p. Xie et al.
a bivalve mollusk shell examined in the hydrated state using Cryo-TEM. J Struct Biol
135:8–17
Lin AYM, Chen PY, Meyers MA (2008) The growth of nacre in the abalone shell. Acta Biomater
4:131–138
Lowenstam HA, Weiner S (1989) On biomineralization. Oxford University Press, New York/
Oxford, pp 99–110
Ma ZJ, Huang J, Sun J, Wang GN, Li CZ, Xie LP, Zhang RQ (2007) A novel extrapallial fluid
protein controls the morphology of nacre lamellae in the pearl oyster, Pinctada fucata. J Biol
Chem 282:23253–23263
Mann S (1993) Molecular tectonics in biomineralization and biomimetic materials chemistry.
Nature 365:499–505
Mann S (2001) Biomineralization: principles and concepts in bioinorganic materials chemistry.
Oxford University Press, Oxford, pp 8, 78, 103–106
Mann K, Weiss IM, Andre S, Gabius HJ, Fritz M (2000) The amino-acid sequence of the abalone
(Haliotis laevigata) nacre protein perlucin – Detection of a functional C-type lectin domain
with galactose/mannose specificity. Eur J Biochem 267:5257–5264
Mann K, Siedler F, Treccani L, Heinemann F, Fritz M (2007) Perlinhibin, a cysteine-, histidine-,
and arginine-rich miniprotein from abalone (Haliotis laevigata) nacre, inhibits in vitro calcium
carbonate crystallization. Biophys J 93:1246–1254
Marin F, Luquet G (2004) Molluscan shell proteins. CR Palevol 3:469–492
Marin F, Luquet G, Marie B, Medakovic D (2008) Molluscan shell proteins: primary structure,
origin, and evolution. Curr Top Dev Biol 80:209–276
Matsushiro A, Miyashita T, Miyamoto H, Morimoto K, Tonomura B, Tanaka A, Sato K (2003)
Presence of protein complex is prerequisite for aragonite crystallization in the nacreous layer.
Mar Biotechnol 5:37–44
Meyers MA, Lin AYM, Chen PY, Muyco J (2008) Mechanical strength of abalone nacre: role of
the soft organic layer. J Mech Behav Biomed 1:76–85
Michenfelder M, Fu G, Lawrence C, Weaver JC, Wustman BA, Taranto L, Evans JS, Morse DE
(2003) Characterization of two molluscan crystal-modulating biomineralization proteins and
identification of putative mineral binding domains. Biopolymers 70:522–533
Miyamoto H, Miyashita T, Okushima M, Nakano S, Morita T, Matsushiro A (1996) A carbonic
anhydrase from the nacreous layer in oyster pearls. Proc Natl Acad Sci USA 93:9657–9660
Miyamoto H, Miyoshi F, Kohno J (2005) The carbonic anhydrase domain protein nacrein is
expressed in the epithelial cells of the mantle and acts as a negative regulator in calcification in
the mollusc Pinctada fucata. Zool Sci 22:311–315
Miyashita T, Takagi R, Okushima M, Nakano S, Miyamoto H, Nishikawa E, Matsushiro A (2000)
Complementary DNA cloning and characterization of pearlin, a new class of matrix protein in
the nacreous layer of oyster pearls. Mar Biotechnol 2:409–418
Miyazaki Y, Nishida T, Aoki H, Samata T (2010) Expression of genes responsible for biomineralization of Pinctada fucata during development. Comp Biochem Phys B 155:241–248
Nakahara H (1981) The Formation and Fine Structure of the Organic Phase of the Nacreous Layer
in Mollusc Shell. In: Mollusk Research (Collection of Assays Contributed in Celebration of
Professor Masae Omori’s 60th Birthday), pp 21–27
Nudelman F, Gotliv BA, Addadi L, Weiner S (2006) Mollusk shell formation: mapping the
distribution of organic matrix components underlying a single aragonitic tablet in nacre.
J Struct Biol 153:176–187
Nudelman F, Chen HH, Goldberg HA, Weiner S, Addadi L (2007) Spiers memorial lecture:
lessons from biomineralization: comparing the growth strategies of mollusc shell prismatic and
nacreous layers in Atrina rigida. Faraday Discuss 136:9–25
Nudelman F, Shimoni E, Klein E, Rousseau M, Bourrat X, Lopez E, Addadi L, Weiner S (2008)
Forming nacreous layer of the shells of the bivalves Atrina rigida and Pinctada margaritifera:
an environmental- and cryo-scanning electron microscopy study. J Struct Biol 162:290–300
350
L.-p. Xie et al.