203
Hasler-Sheetal H, Fragner L, Holmer M, Weckwerth W (2015) Diurnal effects of anoxia on the
metabolome of the seagrass Zostera marina. Metabolomics 11(5):1208–1218
Haznedaroglu MZ, Zeybek U (2007) HPLC determination of chicoric acid in leaves of Posidonia
oceanica. Pharm Biol 45(10):745–748
Kawasaki W, Matsui K, Akakabe Y, Itai N, Kajiwara T (1998) Volatiles from Zostera marina.
Phytochemistry 47(1):27–29
Kim JH, Cho YH, Park SM, Lee KE, Lee JJ, Lee BC et al (2004) Antioxidants and inhibitor
of matrix metalloproteinase-1 expression from leaves of Zostera marina L. Arch Pharm Res
27(2):177–183
Kumar M, Kuzhiumparambil U, Pernice M, Jiang Z, Ralph PJ (2016) Metabolomics: an emerging
frontier of systems biology in marine macrophytes. Algal Res 16:76–92
Laabir M, Grignon-Dubois M, Masseret E, Rezzonico B, Soteras G, Rouquette M et al (2013)
Algicidal effects of Zostera marina L. and Zostera noltii Hornem. Extracts on the neuro-toxic
bloom-forming dinoflagellate Alexandrium catenella. Aquat Bot 111:16–25
Orth RJ, Carruthers TJB, Dennison WC, Duarte CM, Fourqurean JW, Heck KL et al (1976) A
global crisis for seagrass ecosystems. Bioscience 56(12):987–996
Papenbrock J (2012) Highlights in seagrasses phylogeny, physiology, and metabolism: what makes
them special? ISRN Botany 2012:15.17
Quackenbush RC, Bunn D, Lingren W (1986) HPLC determination of phenolic acids in the watersoluble extract of Zostera marina L. (eelgrass). Aquat Bot 24(1):83–89
Ribeiro PR, Fernandez LG, de Castro RD, Ligterink W, Hilhorst HW (2014) Physiological and
biochemical responses of Ricinus communis seedlings to different temperatures: a metabolomics approach. BMC Plant Biol 14(1):223
Subhashini P, Dilipan E, Thangaradjou T, Papenbrock J (2013) Bioactive natural products from
marine angiosperms: abundance and functions. Nat Prod and Bioprospect 3(4):129–136
Taamalli A, Arráez-Román D, Abaza L, Iswaldi I, Fernández-Gutiérrez A, Zarrouk M et al (2015)
LC-MS-based metabolite profiling of methanolic extracts from the medicinal and aromatic
species Mentha pulegium and Origanum majorana. Phytochem Anal 26(5):320–330
Todd JS, Zimmerman RC, Crews P, Alberte RS (1993) The antifouling activity of natural and
synthetic phenol acid sulphate esters. Phytochemistry 34(2):401–404
Vaclavik L, Lacina O, Hajslova J, Zweigenbaum J (2011) The use of high performance liquid
chromatography–quadrupole time-of-flight mass spectrometry coupled to advanced data mining and chemometric tools for discrimination and classification of red wines according to their
variety. Anal Chim Acta 685(1):45–51
Vergeer LHT, Develi A (1997) Phenolic acids in healthy and infected leaves of Zostera marina and
their growth-limiting properties towards Labyrinthula zosterae. Aquat Bot 58(1):65–72
Wang J, Pan X, Han Y, Guo D, Guo Q, Li R (2012) Rosmarinic acid from eelgrass shows nematicidal and antibacterial activities against pine wood nematode and its carrying bacteria. Mar
Drugs 10(12):2729–2740
Zidorn C (2016) Secondary metabolites of seagrasses (Alismatales and Potamogetonales;
Alismatidae): chemical diversity, bioactivity, and ecological function. Phytochemistry
124:5–28
9 Gas and Liquid Chromatography-Mass Spectrometry-Based Metabolic Profiling…
Hasler-Sheetal H, Fragner L, Holmer M, Weckwerth W (2015) Diurnal effects of anoxia on the
metabolome of the seagrass Zostera marina. Metabolomics 11(5):1208–1218
Haznedaroglu MZ, Zeybek U (2007) HPLC determination of chicoric acid in leaves of Posidonia
oceanica. Pharm Biol 45(10):745–748
Kawasaki W, Matsui K, Akakabe Y, Itai N, Kajiwara T (1998) Volatiles from Zostera marina.
Phytochemistry 47(1):27–29
Kim JH, Cho YH, Park SM, Lee KE, Lee JJ, Lee BC et al (2004) Antioxidants and inhibitor
of matrix metalloproteinase-1 expression from leaves of Zostera marina L. Arch Pharm Res
27(2):177–183
Kumar M, Kuzhiumparambil U, Pernice M, Jiang Z, Ralph PJ (2016) Metabolomics: an emerging
frontier of systems biology in marine macrophytes. Algal Res 16:76–92
Laabir M, Grignon-Dubois M, Masseret E, Rezzonico B, Soteras G, Rouquette M et al (2013)
Algicidal effects of Zostera marina L. and Zostera noltii Hornem. Extracts on the neuro-toxic
bloom-forming dinoflagellate Alexandrium catenella. Aquat Bot 111:16–25
Orth RJ, Carruthers TJB, Dennison WC, Duarte CM, Fourqurean JW, Heck KL et al (1976) A
global crisis for seagrass ecosystems. Bioscience 56(12):987–996
Papenbrock J (2012) Highlights in seagrasses phylogeny, physiology, and metabolism: what makes
them special? ISRN Botany 2012:15.17
Quackenbush RC, Bunn D, Lingren W (1986) HPLC determination of phenolic acids in the watersoluble extract of Zostera marina L. (eelgrass). Aquat Bot 24(1):83–89
Ribeiro PR, Fernandez LG, de Castro RD, Ligterink W, Hilhorst HW (2014) Physiological and
biochemical responses of Ricinus communis seedlings to different temperatures: a metabolomics approach. BMC Plant Biol 14(1):223
Subhashini P, Dilipan E, Thangaradjou T, Papenbrock J (2013) Bioactive natural products from
marine angiosperms: abundance and functions. Nat Prod and Bioprospect 3(4):129–136
Taamalli A, Arráez-Román D, Abaza L, Iswaldi I, Fernández-Gutiérrez A, Zarrouk M et al (2015)
LC-MS-based metabolite profiling of methanolic extracts from the medicinal and aromatic
species Mentha pulegium and Origanum majorana. Phytochem Anal 26(5):320–330
Todd JS, Zimmerman RC, Crews P, Alberte RS (1993) The antifouling activity of natural and
synthetic phenol acid sulphate esters. Phytochemistry 34(2):401–404
Vaclavik L, Lacina O, Hajslova J, Zweigenbaum J (2011) The use of high performance liquid
chromatography–quadrupole time-of-flight mass spectrometry coupled to advanced data mining and chemometric tools for discrimination and classification of red wines according to their
variety. Anal Chim Acta 685(1):45–51
Vergeer LHT, Develi A (1997) Phenolic acids in healthy and infected leaves of Zostera marina and
their growth-limiting properties towards Labyrinthula zosterae. Aquat Bot 58(1):65–72
Wang J, Pan X, Han Y, Guo D, Guo Q, Li R (2012) Rosmarinic acid from eelgrass shows nematicidal and antibacterial activities against pine wood nematode and its carrying bacteria. Mar
Drugs 10(12):2729–2740
Zidorn C (2016) Secondary metabolites of seagrasses (Alismatales and Potamogetonales;
Alismatidae): chemical diversity, bioactivity, and ecological function. Phytochemistry
124:5–28
9 Gas and Liquid Chromatography-Mass Spectrometry-Based Metabolic Profiling…