Parallel Genotyping of Different Genes: A Rapid Real-Time peR Approach R
7. Soria LF, Ludwig EH, Clarke HR, Vega GL, Grundy SM, McCarthy BJ (1989) Association
between a specific apolipoprotein B mutation and familial defective apolipoprotein B-lOO.
Proc Natl Acad Sci USA 86:587-591
8. Boren J, Ekstrom U, Agren B, Nilsson-Ehle P, Innerarity TL (2001) The molecular mechanism
for the genetic disorder familial defective apolipoprotein BIOO. J Bioi Chern 276:9214-918
9. Weisgraber KH, Rall SC Jr, Mahley RW (1981) Human E apoprotein heterogeneity. Cysteinearginine interchanges in the amino acid sequence of the apo-E isoforms. J Bioi Chern
256:9077 -9083
10. De Knijff P, van den Maagdenberg AM, Frants RR, Havekes LM (1994) Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels. Hum Mutat
4:178-194
11. Smit M, de Knijff P, van der Kooij-Meijs E, Groenendijk C, van den Maagdenberg AM, Gevers Leuven JA, Stalenhoef AF, Stuyt PM, Frants RR, Havekes LM (1990) Genetic heterogeneity in familial dysbetalipoproteinemia. The E2(lysI46-gln) variant results in a dominant
mode of inheritance. J Lipid Res 31:45-53
12. Smith JD (2000) Apolipoprotein E4: an allele associated with many diseases. Ann Med
32:118-127
13. Lay MJ, Wittwer CT (1997) Real-time fluorescence genotyping of factor V Leiden during rapid-cycle PCR. Clin Chern 43:2262-2267
14. Van den Bergh FA, van Oeveren-Dybicz AM, Bon MA (2000) Rapid single-tube genotyping
of the factor V Leiden and prothrombin mutations by real-time PCR using dual-color detection. Clin Chern 46:1191-1195
15. Parks SB, Popovich BW, Press RD (2001) Real-time polymerase chain reaction with fluorescent hybridization probes for the detection of prevalent mutations causing common thrombophilic and iron overload phenotypes. Am J Clin PathoII15:439-447
16. Ortiz-Pallardo ME, Zhou H, Fischer HP, Neuhaus T, Sachinidis A, Vetter H, Bruning T, Ko Y
(2000) Rapid analysis of alphal-antitrypsin PiZ genotype by a real-time PCR approach. J
Mol Med 78:212-216
7. Soria LF, Ludwig EH, Clarke HR, Vega GL, Grundy SM, McCarthy BJ (1989) Association
between a specific apolipoprotein B mutation and familial defective apolipoprotein B-lOO.
Proc Natl Acad Sci USA 86:587-591
8. Boren J, Ekstrom U, Agren B, Nilsson-Ehle P, Innerarity TL (2001) The molecular mechanism
for the genetic disorder familial defective apolipoprotein BIOO. J Bioi Chern 276:9214-918
9. Weisgraber KH, Rall SC Jr, Mahley RW (1981) Human E apoprotein heterogeneity. Cysteinearginine interchanges in the amino acid sequence of the apo-E isoforms. J Bioi Chern
256:9077 -9083
10. De Knijff P, van den Maagdenberg AM, Frants RR, Havekes LM (1994) Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels. Hum Mutat
4:178-194
11. Smit M, de Knijff P, van der Kooij-Meijs E, Groenendijk C, van den Maagdenberg AM, Gevers Leuven JA, Stalenhoef AF, Stuyt PM, Frants RR, Havekes LM (1990) Genetic heterogeneity in familial dysbetalipoproteinemia. The E2(lysI46-gln) variant results in a dominant
mode of inheritance. J Lipid Res 31:45-53
12. Smith JD (2000) Apolipoprotein E4: an allele associated with many diseases. Ann Med
32:118-127
13. Lay MJ, Wittwer CT (1997) Real-time fluorescence genotyping of factor V Leiden during rapid-cycle PCR. Clin Chern 43:2262-2267
14. Van den Bergh FA, van Oeveren-Dybicz AM, Bon MA (2000) Rapid single-tube genotyping
of the factor V Leiden and prothrombin mutations by real-time PCR using dual-color detection. Clin Chern 46:1191-1195
15. Parks SB, Popovich BW, Press RD (2001) Real-time polymerase chain reaction with fluorescent hybridization probes for the detection of prevalent mutations causing common thrombophilic and iron overload phenotypes. Am J Clin PathoII15:439-447
16. Ortiz-Pallardo ME, Zhou H, Fischer HP, Neuhaus T, Sachinidis A, Vetter H, Bruning T, Ko Y
(2000) Rapid analysis of alphal-antitrypsin PiZ genotype by a real-time PCR approach. J
Mol Med 78:212-216