m Applications in Oncology
human renal cell carcinoma: candidates for T-cell-based immunotherapies. Cancer Res
58:4090-4095
6. Van Baren N, Chambost H, Ferrant A, Michaux L, Ikeda H, Millard I, Olive D, Boon T, Coulie
PG (1998) PRAME, a gene encoding an antigen recognized on a human melanoma by
cytolytic T cells, is expressed in acute leukaemia cells. Br J HaematoI102:1376-1379
7. Greiner J, Ringhoffer M, Simikopinko 0, Szmaragowska A, Maurer U, Bergmann L, Schmitt
M (2000) Simultaneous expression of different immunogenic antigens in acute myeloid
leukemia (AML). Exp J HeamatoI28:1413-1422
8. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium
thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156
9. Bieche I, Laurendeau I, Tozlu S, Olivi M, Vidaud D, Lidereau R, Vidaud M (1999) Quantitation
of MYC Gene Expression in Sporadic Breast Tumors with a Real-Time Reverse Transcription-PCR Assay. Cancer Res 59:2759-2765
10. Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove
J, Ullrich A, Press MF (1998) Studies of the HER-2/neu proto-oncogene in human breast and
ovarian cancer. Science 244:707-712
11. Czuczman MS, Grillo-Lopez AJ, White CA, Saleh M, Gordon L, LoBuglio AF, Jonas C, Klippenstein D, Dallaire B, Yarns C (1999) Treatment of patients with low-grade B-celllymphoma
with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy. J Clin OncoI17:268-276
12. Kessler JH, Beekman NJ, Bres-Vloemans SA, Verdijk P, Veelen van PA, Kloostermann-Joosten AM, Vissers DCJ, Bosch GJA, Kester MGD, Sijts A, Drijthout JW, Ossendorp F, Offringa R,
Melief CJM (2001) Efficient identification of novel HLA-A 0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated
digestion analysis. J Exp Med 193:73-88
13. Bergmann L, Miething C, Maurer U, Brieger J, Karakas T, Weidmann E, Hoelzer D (1997)
High levels of Wilms' tumor gene (wtl) mRNA in acute myeloid leukemias are associated
with a worse long-term outcome. Blood 90(3):1217-25
14. Maurer U, Weidmann E, Karakas T, Hoelzer D, Bergmann L (1997) Wilms tumor gene (wtl)
mRNA is equally expressed in blast cells from acute myeloid leukemia and normal CD34+
progenitors. Blood 90:4230-4232
human renal cell carcinoma: candidates for T-cell-based immunotherapies. Cancer Res
58:4090-4095
6. Van Baren N, Chambost H, Ferrant A, Michaux L, Ikeda H, Millard I, Olive D, Boon T, Coulie
PG (1998) PRAME, a gene encoding an antigen recognized on a human melanoma by
cytolytic T cells, is expressed in acute leukaemia cells. Br J HaematoI102:1376-1379
7. Greiner J, Ringhoffer M, Simikopinko 0, Szmaragowska A, Maurer U, Bergmann L, Schmitt
M (2000) Simultaneous expression of different immunogenic antigens in acute myeloid
leukemia (AML). Exp J HeamatoI28:1413-1422
8. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium
thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156
9. Bieche I, Laurendeau I, Tozlu S, Olivi M, Vidaud D, Lidereau R, Vidaud M (1999) Quantitation
of MYC Gene Expression in Sporadic Breast Tumors with a Real-Time Reverse Transcription-PCR Assay. Cancer Res 59:2759-2765
10. Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove
J, Ullrich A, Press MF (1998) Studies of the HER-2/neu proto-oncogene in human breast and
ovarian cancer. Science 244:707-712
11. Czuczman MS, Grillo-Lopez AJ, White CA, Saleh M, Gordon L, LoBuglio AF, Jonas C, Klippenstein D, Dallaire B, Yarns C (1999) Treatment of patients with low-grade B-celllymphoma
with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy. J Clin OncoI17:268-276
12. Kessler JH, Beekman NJ, Bres-Vloemans SA, Verdijk P, Veelen van PA, Kloostermann-Joosten AM, Vissers DCJ, Bosch GJA, Kester MGD, Sijts A, Drijthout JW, Ossendorp F, Offringa R,
Melief CJM (2001) Efficient identification of novel HLA-A 0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated
digestion analysis. J Exp Med 193:73-88
13. Bergmann L, Miething C, Maurer U, Brieger J, Karakas T, Weidmann E, Hoelzer D (1997)
High levels of Wilms' tumor gene (wtl) mRNA in acute myeloid leukemias are associated
with a worse long-term outcome. Blood 90(3):1217-25
14. Maurer U, Weidmann E, Karakas T, Hoelzer D, Bergmann L (1997) Wilms tumor gene (wtl)
mRNA is equally expressed in blast cells from acute myeloid leukemia and normal CD34+
progenitors. Blood 90:4230-4232