22
G. Jansen et al.
gpa-1 •
I . . .
,
••• ,
gpa-2 •
••• If ••
gpa-3 • .,.," ,
gpa-4, ••• • • ••
,
gpa-5, ••••• ~ • •
gpa-6 •••••
•••
gpa-7 iL. ______ ...I ..... L..J. __ ..... ---, , . . . . . .
L----...J
gpa-8 T ........ .
,
I
gpa-9 ~I'.' ....
,
gpa,10 •• ••• "", •
gpa-11 _ _ ~, =='~I~_~,:-.
• i ,
gpa-12 '," ••••
gpa-13, I •• • • • • •
gpa-14 I •
• • •
• •• ,
gpa-15 • 'L..!, .' •••
gpa-16 I
•
•
... • •
,
odr-3 i. • • • •
goa-1 • •
'"
I I
•• •
gsa-1
• • • ••• •
•
eg/-30 •
• ••• • • •
Fig. 4. Predicted gene structure and mutant alleles of the G protein a subunit
genes of C. elegans. Exons are represented by black boxes. For some genes
transposon Tel insertion alleles have been isolated, indicated with triangles.
Brackets show the regions deleted in the knockout alleles. The gene structure
and mutant alleles of several Ga genes have been reported previously: gpa-2
and -3 (Zwaal et al. 1997); odr-3 (Roayaie et al. 1998), the position of the nonsense mutation present in allele n1605 is indicated with an arrow; goa-l (Lochrie et al. 1991), the Tcl insertion in allele pk62 is indicated (Mendel et al.
1995); gsa-l (Park et al. 1997), the deletion present in allele pk75 is given
(Korswagen et al. 1997); egl-30 (Brundage et al. 1996), many different alleles
exist. none of these are indicated