234
E. C. Bailey et al.
Rosenthal A (1996) The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384:129-134
Tabata T, Eaton S, Kornberg TB (1992) The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes Dev 6:2635-2645
Takabatake T, Ogawa M, Takahashi TC, Mizuno M, Okamoto M, Takeshima K
(1997) Hedgehog and patched gene expression in adult ocular tissues.
FEBS Lett 410:485-489
Tashiro S, Michiue T, Higashijima S, Zenno S, Ishimaru S, Takahashi F, Orihara M, Kojima T, Saigo K (1993) Structure and expression of hedgehog,
a Drosophila segment-polarity gene required for cell-cell communication.
Gene 124:183-189
Taylor AM, Nakano Y, Mohler J, Ingham PW (1993) Contrasting distributions
of patched and hedgehog proteins in the Drosophila embryo. Mech Dev
42:89-96
Theodosiou NA, Zhang S, Wang WY, Xu T (1998) slimb coordinates wg and
dpp expression in the dorsal-ventral and anterior-posterior axes during limb
development. Development 125:3411-3416
Valentini RP, Brookhiser WT, Park J, Yang T, Briggs J, Dressler G, Holzman
LB (1997) Post-translational processing and renal expression of mouse Indian hedgehog. J BioI Chern 272:8466-8473
van den Heuvel M, Ingham PW (1996) smoothened encodes a receptor-like
serpentine protein required for hedgehog signalling. Nature 382:547-551
Vorechovsky I, Tingby 0, Hartman M, Stromberg B, Nister M, Collins VP,
Toftgard R (1997) Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours. Oncogene 15:361-366
Vorechovsky I, Unden AB, Sandstedt B, Toftgard R, Stahle-Backdahl M
(1997) Trichoepitheliomas contain somatic mutations in the overexpressed
PTCH gene: support for a gatekeeper mechanism in skin tumorigenesis.
Cancer Res 57:4677-4681
Vortkamp A, Gessler M, Grzeschik KH (1991) GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families. Nature 352:539-540
Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ (1996)
Regulation of rate of cartilage differentiation by Indian hedgehog and PTHrelated protein. Science 273:613-622
Wicking C, Shanley S, Smyth I, Gillies S, Negus K, Graham S, Suthers G,
Haites N, Edwards M, Wainwright B, Chenevix-Trench G (1997) Most
germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a
premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. Am J Hum Genet 60:21-26
E. C. Bailey et al.
Rosenthal A (1996) The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384:129-134
Tabata T, Eaton S, Kornberg TB (1992) The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes Dev 6:2635-2645
Takabatake T, Ogawa M, Takahashi TC, Mizuno M, Okamoto M, Takeshima K
(1997) Hedgehog and patched gene expression in adult ocular tissues.
FEBS Lett 410:485-489
Tashiro S, Michiue T, Higashijima S, Zenno S, Ishimaru S, Takahashi F, Orihara M, Kojima T, Saigo K (1993) Structure and expression of hedgehog,
a Drosophila segment-polarity gene required for cell-cell communication.
Gene 124:183-189
Taylor AM, Nakano Y, Mohler J, Ingham PW (1993) Contrasting distributions
of patched and hedgehog proteins in the Drosophila embryo. Mech Dev
42:89-96
Theodosiou NA, Zhang S, Wang WY, Xu T (1998) slimb coordinates wg and
dpp expression in the dorsal-ventral and anterior-posterior axes during limb
development. Development 125:3411-3416
Valentini RP, Brookhiser WT, Park J, Yang T, Briggs J, Dressler G, Holzman
LB (1997) Post-translational processing and renal expression of mouse Indian hedgehog. J BioI Chern 272:8466-8473
van den Heuvel M, Ingham PW (1996) smoothened encodes a receptor-like
serpentine protein required for hedgehog signalling. Nature 382:547-551
Vorechovsky I, Tingby 0, Hartman M, Stromberg B, Nister M, Collins VP,
Toftgard R (1997) Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours. Oncogene 15:361-366
Vorechovsky I, Unden AB, Sandstedt B, Toftgard R, Stahle-Backdahl M
(1997) Trichoepitheliomas contain somatic mutations in the overexpressed
PTCH gene: support for a gatekeeper mechanism in skin tumorigenesis.
Cancer Res 57:4677-4681
Vortkamp A, Gessler M, Grzeschik KH (1991) GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families. Nature 352:539-540
Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ (1996)
Regulation of rate of cartilage differentiation by Indian hedgehog and PTHrelated protein. Science 273:613-622
Wicking C, Shanley S, Smyth I, Gillies S, Negus K, Graham S, Suthers G,
Haites N, Edwards M, Wainwright B, Chenevix-Trench G (1997) Most
germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a
premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident. Am J Hum Genet 60:21-26