230
References
Aparna V, Dileep KV, Mandal PK, Karthe P, Sadasivan C, Haridas M (2012) Anti-inflammatory
property of n-hexadecanoic acid: structural evidence and kinetic assessment. Chem Biol Drug
Des 80:434–439. doi:10.1111/j.1747-0285.2012.01418
Ashley NT, Weil ZM, Nelson RJ (2012) Inflammation: mechanisms, costs, and natural variation.
Annu Rev Ecol Evol Syst 43:385–406. doi:10.1146/annurev-ecolsys-040212-092530
Batt DG (1992) 5-lipoxygenase inhibitors and their anti-inflammatory activities. Prog Med Chem
29:1–63
Brash AR (1999) Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate.
J Biol Chem 274:23679–23682. doi:10.1074/jbc.274.34.23679
Burke JE, Dennis EA (2009) Phospholipase A2 structure/function, mechanism, and signalling.
J Lipid Res 50:S237–S242. doi:10.1194/jlr.R800033-JLR200
Cao H, Yu R, Choi Y, Ma ZZ, Zhang H, Xiang W, Lee DY, Berman BM, Moudgil KD, Fong HH,
van Breemen RB (2010) Discovery of cyclooxygenase inhibitors from medicinal plants used to
treat inflammation. Pharmacol Res 61:519–524. doi:10.1016/j.phrs.2010.02
Chandra DN, Prasanth GK, Singh N, Kumar S, Jithesh O, Sadasivan C, Sharma S, Singh TP,
Haridas M (2011) Identification of a novel and potent inhibitor of phospholipase A2 in a medicinal plant: crystal structure at 1.93 Å and surface Plasmon resonance analysis of phospholipase
A2 complexed with berberine. Biochim et Biophys Acta (BBA) – Proteins and Proteomics
1814:657–663. doi:10.1016/j.bbapap.2011.03.002
Chandra DN, Preethidan DS, Sabu A, Haridas M, (2015) Traditional fermentation of ayurvedic
medicine yields higher proinflammatory enzyme inhibition compared to wine-model product.
Front in Life Sci 8(2): 160–164. doi: http://dx.doi.org/10.1080/21553769.2015.1005245
Chauret N, Yergey JA, Brideau C, Friesen RW, Mancini J, Riendeau D, Silva J, Styhler A, Trimble
LA, Nicoll-Griffith DA, (2001) In vitro metabolism considerations, including activity testing
of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663).
Bioorg Med Chem Lett 11: 1059–1062. doi: http://dx.doi.org/10.1016/S0960-894X(01)00135-4
Chi YS, Jong HG, Son KH, Chang HW, Kang SS, Kim HP (2001) Effects of naturally occurring
prenylated flavonoids on enzymes metabolizing arachidonic acid: cyclooxygenases and lipoxygenases. Biochem Pharmacol 62:1185–1191
Cholbi R, Ferrándiz ML, Terencio MC, De Rosa S, Alcaraz MJ, Payá M (1996) Inhibition of
phospholipase A2 activities and some inflammatory responses by the marine product ircinin.
Naunyn Schmiedeberg’s Arch Pharmacol 354(5):677–683
Davidson FF, Hajdu J, Dennis EA (1986) 1-stearyl,2-stearoylaminodeoxy phosphatidylcholine, a
potent reversible inhibitor of phospholipase A2. Biochem Biophys Res Commun 137:587–592
De Haas GH, van Oort MG, Dijkman R, Verger R (1989) Phospholipase A2 inhibitors: monoacyl,
monoacylamino-glycero-phosphocholines. Biochem Soc Trans 17:274–276
Dennis EA, Cao J, Hsu YH, Magrioti V, Kokotos G (2011) Phospholipase A2 enzymes: physical
structure, biological function, disease implication, chemical inhibition, and therapeutic intervention. Chem Rev 111:6130–6185
DeWitt DL (1999) Cox-2-selective inhibitors: the new super aspirins. Mol Pharmacol 55:625–631
Dhanjal JK, Sreenidhi AK, Bafna K, Katiyar SP, Goyal S, Grover A, Sundar D (2015) Computational
structure-based de novo design of hypothetical inhibitors against the anti-inflammatory target
COX-2. PLoS One 10:e0134691. doi:10.1371/journal.pone.0134691
Dileep KV, Tintu I, Sadasivan C (2011) Molecular docking studies of curcumin analogs with phospholipase A2. Interdiscip Sci: Comput Life Sci 3:189–197. doi:10.1007/s12539-011-0090-9
Dileep KV, Remya C, Tintu I, Haridas M, Sadasivan C (2013) Interactions of selected indole
derivatives with phospholipase A2: in silico and in vitro analysis. J Mol Model 19:1811–1817.
doi:10.1007/s00894-012-1741-4
C.S. Sharanya and M. Haridas
References
Aparna V, Dileep KV, Mandal PK, Karthe P, Sadasivan C, Haridas M (2012) Anti-inflammatory
property of n-hexadecanoic acid: structural evidence and kinetic assessment. Chem Biol Drug
Des 80:434–439. doi:10.1111/j.1747-0285.2012.01418
Ashley NT, Weil ZM, Nelson RJ (2012) Inflammation: mechanisms, costs, and natural variation.
Annu Rev Ecol Evol Syst 43:385–406. doi:10.1146/annurev-ecolsys-040212-092530
Batt DG (1992) 5-lipoxygenase inhibitors and their anti-inflammatory activities. Prog Med Chem
29:1–63
Brash AR (1999) Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate.
J Biol Chem 274:23679–23682. doi:10.1074/jbc.274.34.23679
Burke JE, Dennis EA (2009) Phospholipase A2 structure/function, mechanism, and signalling.
J Lipid Res 50:S237–S242. doi:10.1194/jlr.R800033-JLR200
Cao H, Yu R, Choi Y, Ma ZZ, Zhang H, Xiang W, Lee DY, Berman BM, Moudgil KD, Fong HH,
van Breemen RB (2010) Discovery of cyclooxygenase inhibitors from medicinal plants used to
treat inflammation. Pharmacol Res 61:519–524. doi:10.1016/j.phrs.2010.02
Chandra DN, Prasanth GK, Singh N, Kumar S, Jithesh O, Sadasivan C, Sharma S, Singh TP,
Haridas M (2011) Identification of a novel and potent inhibitor of phospholipase A2 in a medicinal plant: crystal structure at 1.93 Å and surface Plasmon resonance analysis of phospholipase
A2 complexed with berberine. Biochim et Biophys Acta (BBA) – Proteins and Proteomics
1814:657–663. doi:10.1016/j.bbapap.2011.03.002
Chandra DN, Preethidan DS, Sabu A, Haridas M, (2015) Traditional fermentation of ayurvedic
medicine yields higher proinflammatory enzyme inhibition compared to wine-model product.
Front in Life Sci 8(2): 160–164. doi: http://dx.doi.org/10.1080/21553769.2015.1005245
Chauret N, Yergey JA, Brideau C, Friesen RW, Mancini J, Riendeau D, Silva J, Styhler A, Trimble
LA, Nicoll-Griffith DA, (2001) In vitro metabolism considerations, including activity testing
of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663).
Bioorg Med Chem Lett 11: 1059–1062. doi: http://dx.doi.org/10.1016/S0960-894X(01)00135-4
Chi YS, Jong HG, Son KH, Chang HW, Kang SS, Kim HP (2001) Effects of naturally occurring
prenylated flavonoids on enzymes metabolizing arachidonic acid: cyclooxygenases and lipoxygenases. Biochem Pharmacol 62:1185–1191
Cholbi R, Ferrándiz ML, Terencio MC, De Rosa S, Alcaraz MJ, Payá M (1996) Inhibition of
phospholipase A2 activities and some inflammatory responses by the marine product ircinin.
Naunyn Schmiedeberg’s Arch Pharmacol 354(5):677–683
Davidson FF, Hajdu J, Dennis EA (1986) 1-stearyl,2-stearoylaminodeoxy phosphatidylcholine, a
potent reversible inhibitor of phospholipase A2. Biochem Biophys Res Commun 137:587–592
De Haas GH, van Oort MG, Dijkman R, Verger R (1989) Phospholipase A2 inhibitors: monoacyl,
monoacylamino-glycero-phosphocholines. Biochem Soc Trans 17:274–276
Dennis EA, Cao J, Hsu YH, Magrioti V, Kokotos G (2011) Phospholipase A2 enzymes: physical
structure, biological function, disease implication, chemical inhibition, and therapeutic intervention. Chem Rev 111:6130–6185
DeWitt DL (1999) Cox-2-selective inhibitors: the new super aspirins. Mol Pharmacol 55:625–631
Dhanjal JK, Sreenidhi AK, Bafna K, Katiyar SP, Goyal S, Grover A, Sundar D (2015) Computational
structure-based de novo design of hypothetical inhibitors against the anti-inflammatory target
COX-2. PLoS One 10:e0134691. doi:10.1371/journal.pone.0134691
Dileep KV, Tintu I, Sadasivan C (2011) Molecular docking studies of curcumin analogs with phospholipase A2. Interdiscip Sci: Comput Life Sci 3:189–197. doi:10.1007/s12539-011-0090-9
Dileep KV, Remya C, Tintu I, Haridas M, Sadasivan C (2013) Interactions of selected indole
derivatives with phospholipase A2: in silico and in vitro analysis. J Mol Model 19:1811–1817.
doi:10.1007/s00894-012-1741-4
C.S. Sharanya and M. Haridas