198
Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters
from Erythroxylum pervillei. J Nat Prod 64:1514–1520
Singh RH (2002) An assessment of the ayurvedic concept of cancer and a new paradigm of anticancer treatment in Ayurveda. J Altern Complement Med 8:609–614
Siwak DR, Shishodia S, Aggarwal BB, Kurzrock R (2005) Curcumin-induced antiproliferative
and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase
and nuclear factor kappaB activity and are independent of the B-Raf/mitogen activated/extracellular signal-regulated protein kinase pathway and the Akt pathway. Cancer 104:879–890
Soumya B, Andre P, Brahim M, Jean L (2011) Antioxidant, anti-inflammatory, anticancer and
antibacterial activities of extracts from Nigella sativa (Black Cumin) plant parts. J Food Chem
36:539–546
Srivastava V, Negi AS, Kumar JK, Gupta MM, Khanuja SPS (2005) Plant-based anticancer
molecules: a chemical and biological profile of some important leads. Bioorg Med Chem
13:5892–5908
Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB Jr, Stewart L (2002) The mechanism of topoisomerase I poisoning by a camptothecin analog. Proc Natl Acad Sci U S A
99:15387–15392
Susruta (700 BC) Susruta Samhita. Chaukhamba Surbharati Publications. Varanasi
The wealth of India (1985) A dictionary of Indian raw materials and industrial products vol –I
(A-B). Council of Scientific & Industrial Research, New Delhi, p 29
Tozer GM, Prise VE, Wilson J, Locke RJ, Vojnovic B, Stratford MR, Dennis MF, Chaplin DJ
(1999) Combretastatin A-4 phosphate as a tumour vascular-targeting agent: early effects in
tumours and normal tissues. Cancer Res 59:626–634
Tron GC, Pirali T, Sorba G, Pagliai F, Busacca S, Genazzani AA (2006) Medicinal chemistry of
combretastatin A4: present and future directions. J Med Chem 49:3033–3044
Tsubura A, Lai YC, Kuwata M, Uehara N, Yoshizawa K (2011) Anticancer effects of garlic
and garlic- derived compounds for breast cancer control. Anti Cancer Agents Med Chem
11:249–253
Tyler V (1994) Herbs of choice: the therapeutic use of phytomedicinals. Haworth Press, New York,
pp 32–33
Usami Y, Nakagawa GK, Lang JY, Kim Y, Lai CY, Goto M, Sakurai N, Taniguchi M, Akiyama
T, Morris NSL, Bastow KF, Cragg G, Newman DJ, Fujitakeo M, Takeya K, Hung MC, Lee
EYHP, Lee KH (2010) Antitumor agents. 282. 2′-(R)-O-acetylglaucarubinone, a quassinoid
from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent. J Nat
Prod 73:1553–1558
Vetrivel U, Subramanian N, Pilla K (2009) InPACdb Indian plant anticancer compounds database.
Bioinformation 4:71–74
Vyas AR, Singh SV (2014) Molecular targets and mechanisms of cancer prevention and treatment
by withaferin a, a naturally occurring steroidal lactone. Am Ass Pharm Sci J 16:1–10
Wall ME (1998) Camptothecin and taxol: discovery to clinic. Med Res Rev 18:299–314
Wall ME, Wani MC, Cook CE, Palmer KH, McPhail AI, Sim GA (1966) Plant antitumor agents
I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor
from Camptotheca acuminata. J Am Chem Soc 88:3888–3890
Winking M, Sarikaya S, Rahmanian A, Jodicke A, Boker DK (2000) Boswellic acids inhibit glioma growth: a new treatment option? J Neuro-Oncol 46:97–103
Xu Y, Tian F, Li R, Liu Z (2009) Tanshinone II-A inhibits invasion and metastasis of human hepatocellular carcinoma cells in vitro and in vivo. Tumori 95:789–795
Yadav VR, Prasad S, Sung B, Gelovani JG, Guha S, Krishnan S, Aggarwal BB (2012) Boswellic
acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by
down regulating inflammatory, proliferative, invasive, and angiogenic biomarkers. Int J Cancer
J Int Du Cancer 130:2176–2184
Yan C, Jamaluddin MS, Aggarwal B, Myers J, Boyd DD (2005) Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin. Mol Cancer Ther 4:233–241
A. Augustine and G.S. Pillai
Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters
from Erythroxylum pervillei. J Nat Prod 64:1514–1520
Singh RH (2002) An assessment of the ayurvedic concept of cancer and a new paradigm of anticancer treatment in Ayurveda. J Altern Complement Med 8:609–614
Siwak DR, Shishodia S, Aggarwal BB, Kurzrock R (2005) Curcumin-induced antiproliferative
and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase
and nuclear factor kappaB activity and are independent of the B-Raf/mitogen activated/extracellular signal-regulated protein kinase pathway and the Akt pathway. Cancer 104:879–890
Soumya B, Andre P, Brahim M, Jean L (2011) Antioxidant, anti-inflammatory, anticancer and
antibacterial activities of extracts from Nigella sativa (Black Cumin) plant parts. J Food Chem
36:539–546
Srivastava V, Negi AS, Kumar JK, Gupta MM, Khanuja SPS (2005) Plant-based anticancer
molecules: a chemical and biological profile of some important leads. Bioorg Med Chem
13:5892–5908
Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB Jr, Stewart L (2002) The mechanism of topoisomerase I poisoning by a camptothecin analog. Proc Natl Acad Sci U S A
99:15387–15392
Susruta (700 BC) Susruta Samhita. Chaukhamba Surbharati Publications. Varanasi
The wealth of India (1985) A dictionary of Indian raw materials and industrial products vol –I
(A-B). Council of Scientific & Industrial Research, New Delhi, p 29
Tozer GM, Prise VE, Wilson J, Locke RJ, Vojnovic B, Stratford MR, Dennis MF, Chaplin DJ
(1999) Combretastatin A-4 phosphate as a tumour vascular-targeting agent: early effects in
tumours and normal tissues. Cancer Res 59:626–634
Tron GC, Pirali T, Sorba G, Pagliai F, Busacca S, Genazzani AA (2006) Medicinal chemistry of
combretastatin A4: present and future directions. J Med Chem 49:3033–3044
Tsubura A, Lai YC, Kuwata M, Uehara N, Yoshizawa K (2011) Anticancer effects of garlic
and garlic- derived compounds for breast cancer control. Anti Cancer Agents Med Chem
11:249–253
Tyler V (1994) Herbs of choice: the therapeutic use of phytomedicinals. Haworth Press, New York,
pp 32–33
Usami Y, Nakagawa GK, Lang JY, Kim Y, Lai CY, Goto M, Sakurai N, Taniguchi M, Akiyama
T, Morris NSL, Bastow KF, Cragg G, Newman DJ, Fujitakeo M, Takeya K, Hung MC, Lee
EYHP, Lee KH (2010) Antitumor agents. 282. 2′-(R)-O-acetylglaucarubinone, a quassinoid
from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent. J Nat
Prod 73:1553–1558
Vetrivel U, Subramanian N, Pilla K (2009) InPACdb Indian plant anticancer compounds database.
Bioinformation 4:71–74
Vyas AR, Singh SV (2014) Molecular targets and mechanisms of cancer prevention and treatment
by withaferin a, a naturally occurring steroidal lactone. Am Ass Pharm Sci J 16:1–10
Wall ME (1998) Camptothecin and taxol: discovery to clinic. Med Res Rev 18:299–314
Wall ME, Wani MC, Cook CE, Palmer KH, McPhail AI, Sim GA (1966) Plant antitumor agents
I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor
from Camptotheca acuminata. J Am Chem Soc 88:3888–3890
Winking M, Sarikaya S, Rahmanian A, Jodicke A, Boker DK (2000) Boswellic acids inhibit glioma growth: a new treatment option? J Neuro-Oncol 46:97–103
Xu Y, Tian F, Li R, Liu Z (2009) Tanshinone II-A inhibits invasion and metastasis of human hepatocellular carcinoma cells in vitro and in vivo. Tumori 95:789–795
Yadav VR, Prasad S, Sung B, Gelovani JG, Guha S, Krishnan S, Aggarwal BB (2012) Boswellic
acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by
down regulating inflammatory, proliferative, invasive, and angiogenic biomarkers. Int J Cancer
J Int Du Cancer 130:2176–2184
Yan C, Jamaluddin MS, Aggarwal B, Myers J, Boyd DD (2005) Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin. Mol Cancer Ther 4:233–241
A. Augustine and G.S. Pillai