196
Liu RH (2004) Potential synergy of phytochemicals in cancer prevention: mechanism of action.
Supplement to the international research conference on food, nutrition, and cancer. J Nutr
134:3479S–3485S
Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD (2002) Boswellic acids trigger
apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand
interaction in colon cancer HT-29 cells. Carcinogenesis 23:2087–2093
Majumdar AP, Banerjee S, Nautiyal J, Patel BB, Patel V, Du J, Yu Y, Elliott AA, Levi E, Sarkar FH
(2009) Curcumin synergizes with resveratrol to inhibit colon cancer. Nutr Cancer 61:544–553
Mangal M, Sagar P, Singh H, Raghava GPS, Agarwal SM (2013) NPACT: naturally occurring
plant-based anti-cancer compound-activity-target database. Nucleic Acids Res 41(Database
issue):D1124–D1129
Mans DRA, Da Rocha A, Schwartsmann G (2000) Anti-cancer drug discovery and development
in Brazil: targeted plant collection as a rational strategy to acquire candidate anti-cancer compounds. Oncologist 5:185–198
Massi P, Solinas M, Cinquina V, Parolaro D (2012) Cannabidiol as potential anticancer drug. Br
J Clin Pharmacol 75:303–312
McGowan AT, Fox BW (1990) Differential cytotoxicity of the combretastatins A1 and A4 in two
daunorubicin P388 resistant cell lines. Cancer Chemother Pharmacol 26:79–81
Mi Q, Lantvit D, Reyes-Lim E, Chai H, Phifer SS, Wani MC, Wall ME, Tan GT, Cordell GA,
Farnsworth NR, Douglas KA, Pezzuto JM (2005) Apoptotic anticancer effect of alvaradoin E
isolated from Alvaradoa Haitiensis. Anticancer Res 2005:779–787
Mishra A, Sharma AK, Kumar S, Ajit KS, Abhay KP (2013) Bauhinia variegata Leaf extracts
exhibit considerable antibacterial, antioxidant, and anticancer activities. Biomed Res Int
2013:1–10
Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB (2001) Curcumin
downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene
20:7597–7609
Naik GH, Priyadarshini KI, Bhagirathi RG et al (2005) In vitro antioxidant studies and free
radical reactions of triphala, an ayurvedic formulation and its constituents. Phytother Res
19:582–586
Nam NH (2003) Combretastatin A-4 analogues as antimitotic antitumor agents. Curr Med Chem
10:1697–1722
Neeta, Dureja H (2014) Role of Boswellic acids in cancer treatment. J Med Sci 14:261–269
Newman DJ, Cragg GM, Snader KM (2003) Natural products as sources of new drugs over the
period 1981-2002. J Nat Prod 66:1022–1037
Ohsumi K, Nakagawa R, Fukuda Y, Hatanaka T, Morinaga Y, Nihei Y, Ohishi K, Suga Y, Akiyama
Y, Tsuji T (1998) Novel combretastatin analogues effective against murine solid tumors: design
and structure-activity relationships. J Med Chem 41:3022–3032
Pan L, Chai HB, Kinghorn AD (2012) Discovery of new anticancer agents from higher plants.
Front Biosci 4:142–156
Park B, Sung B, Yadav VR, Cho SG, Liu M, Aggarwal BB (2011) Acetyl-11-keto-β-Boswellic
acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4
chemokine receptor expression. Int J Cancer 129:23–33
Patel VB, Misra S, Patel BB, Majumdar APN (2010) Colorectal cancer: Chemopreventive role of
curcumin and resveratrol. Nutr Cancer 62:958–967
Pecere T, Gazzola MV, Micignat C, Parolin C, Vecchia FD, Cavaggioni A, Basso G, Diaspro A,
Salvato B, Carli M, Palù G (2000) Aloe-emodin is a new type of anticancer agent with selective
activity against neuro-ectodermal tumors. Cancer Res 60:2800–2804
Pettit GR (1995) The scientific contributions of Jonathan L. Hartwell, PH.D. J Nat Prod 58:359–364
Pettit GR, Singh SB, Niven ML, Hamel E, Schmidt JM (1987) Isolation, structure, and synthesis
of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from
Combretum Caffrum. J Nat Prod 50:119–131
A. Augustine and G.S. Pillai
Liu RH (2004) Potential synergy of phytochemicals in cancer prevention: mechanism of action.
Supplement to the international research conference on food, nutrition, and cancer. J Nutr
134:3479S–3485S
Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD (2002) Boswellic acids trigger
apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand
interaction in colon cancer HT-29 cells. Carcinogenesis 23:2087–2093
Majumdar AP, Banerjee S, Nautiyal J, Patel BB, Patel V, Du J, Yu Y, Elliott AA, Levi E, Sarkar FH
(2009) Curcumin synergizes with resveratrol to inhibit colon cancer. Nutr Cancer 61:544–553
Mangal M, Sagar P, Singh H, Raghava GPS, Agarwal SM (2013) NPACT: naturally occurring
plant-based anti-cancer compound-activity-target database. Nucleic Acids Res 41(Database
issue):D1124–D1129
Mans DRA, Da Rocha A, Schwartsmann G (2000) Anti-cancer drug discovery and development
in Brazil: targeted plant collection as a rational strategy to acquire candidate anti-cancer compounds. Oncologist 5:185–198
Massi P, Solinas M, Cinquina V, Parolaro D (2012) Cannabidiol as potential anticancer drug. Br
J Clin Pharmacol 75:303–312
McGowan AT, Fox BW (1990) Differential cytotoxicity of the combretastatins A1 and A4 in two
daunorubicin P388 resistant cell lines. Cancer Chemother Pharmacol 26:79–81
Mi Q, Lantvit D, Reyes-Lim E, Chai H, Phifer SS, Wani MC, Wall ME, Tan GT, Cordell GA,
Farnsworth NR, Douglas KA, Pezzuto JM (2005) Apoptotic anticancer effect of alvaradoin E
isolated from Alvaradoa Haitiensis. Anticancer Res 2005:779–787
Mishra A, Sharma AK, Kumar S, Ajit KS, Abhay KP (2013) Bauhinia variegata Leaf extracts
exhibit considerable antibacterial, antioxidant, and anticancer activities. Biomed Res Int
2013:1–10
Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB (2001) Curcumin
downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene
20:7597–7609
Naik GH, Priyadarshini KI, Bhagirathi RG et al (2005) In vitro antioxidant studies and free
radical reactions of triphala, an ayurvedic formulation and its constituents. Phytother Res
19:582–586
Nam NH (2003) Combretastatin A-4 analogues as antimitotic antitumor agents. Curr Med Chem
10:1697–1722
Neeta, Dureja H (2014) Role of Boswellic acids in cancer treatment. J Med Sci 14:261–269
Newman DJ, Cragg GM, Snader KM (2003) Natural products as sources of new drugs over the
period 1981-2002. J Nat Prod 66:1022–1037
Ohsumi K, Nakagawa R, Fukuda Y, Hatanaka T, Morinaga Y, Nihei Y, Ohishi K, Suga Y, Akiyama
Y, Tsuji T (1998) Novel combretastatin analogues effective against murine solid tumors: design
and structure-activity relationships. J Med Chem 41:3022–3032
Pan L, Chai HB, Kinghorn AD (2012) Discovery of new anticancer agents from higher plants.
Front Biosci 4:142–156
Park B, Sung B, Yadav VR, Cho SG, Liu M, Aggarwal BB (2011) Acetyl-11-keto-β-Boswellic
acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4
chemokine receptor expression. Int J Cancer 129:23–33
Patel VB, Misra S, Patel BB, Majumdar APN (2010) Colorectal cancer: Chemopreventive role of
curcumin and resveratrol. Nutr Cancer 62:958–967
Pecere T, Gazzola MV, Micignat C, Parolin C, Vecchia FD, Cavaggioni A, Basso G, Diaspro A,
Salvato B, Carli M, Palù G (2000) Aloe-emodin is a new type of anticancer agent with selective
activity against neuro-ectodermal tumors. Cancer Res 60:2800–2804
Pettit GR (1995) The scientific contributions of Jonathan L. Hartwell, PH.D. J Nat Prod 58:359–364
Pettit GR, Singh SB, Niven ML, Hamel E, Schmidt JM (1987) Isolation, structure, and synthesis
of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from
Combretum Caffrum. J Nat Prod 50:119–131
A. Augustine and G.S. Pillai