240
G. BiiLDT et al.: Structure, Dynamics and Function of the Proton Pump Bacteriorhodopsin
Rammelsberg R, HeEling B, Chorongiewski H, Gerwert K (1997) Molecular Reaction Mechanism of
Proteins Monitored by Nanosecond Step-Scan FT-IR Difference Spectroscopy. Appl.Spectrosc.
51:558-562.
R6dig C, Chizhov I, Weidlich 0, Siebert F (1999) Time-Resolved Step-Scan Fourier Transform Infrared Spectroscopy Reveals Differences between Early and Late M Intermediates of Bacteriorhodopsin. Biophys] 76:2687-2701.
Schertler G F X, Bartunik H D, Michel H, Oesterhelt D (1993) Orthorhombic crystal form of bacteriorhodopsin nucleated on benzamidine diffracting to 3.6 A. J. Mol. BioI. 234, 156-164
Siebert F (1990) Resonance Raman and infrared difference spectroscopy of retinal proteins. Methods
EnzymoI189:123-136.
Takeda K, Sato H, Hino T, Kono M, Fukuda K, Sakurai I, Okada T, Kouyama T (1998) A Novel Threedimensional Crystal of Bacteriorhodopsin Obtained by Successive Fusion of the Vesicular Assemblies. J. Mol. BioI. 283,463-474
Thiedemann G, Heberle J, Dencher N A (1992) Structures and Functions of Retinal Proteins. Colloque
ENSERM/John Libbey Eurotext Ltd, Vol. 221, 217
Trewhella J, Popot J L, Zaccai G, Engelman D M (1986) Localization of two chymotryptic fragments
in the structure of renatured Bacteriorhodopsin by neutron diffraction. EMBO J. 5, 3045-3049
Trewhella J, Anderson S, Fox R, Gogol E, Khan S, Engelman D, Zaccai G. (1983) Assignment of Segments of the Bacteriorhodopsin to Positions in the Structural Map. Biophys. J. 42, 233-241
Unwin P N T, Henderson R J (1975) Molecular Structure Determination by Electron Microscopy of
Unstained Crystalline Specimens. J. Mol. BioI. 94, 425-440
Varo G, Lanyi J (1990) Pathways of the rise and decay of the M photointermediate(s) of bacteriorhodopsin. Biochemistry 29,2241-2250
Weidlich 0, Siebert F (1993) Time Resolved Step-Scan FTIR Investigations of the Transition from KL
to L in the Bacteriorhodpsin Photocycle: Identification of Chromophore Twists by Assigning
Hydrogen-Out-Of-Plane (HOOP) Bending Vibrations. Appl.Spectrosc. 47:1394-1400.
Zaccai G, Gilmore D J (1979) Areas ofhydration,)n the purple membrane of Halobacterium halobium:
a neutron diffraction study. J. Mol. BioI. 132, 181-191
Zscherp C, Heberle J (1997) Infrared difference spectra of the intermediates L, M, N, and 0 of the bacteriorhodopsin photoreaction obtained by time-resolved attenuated total reflection spectroscopy.
].Phys.Chem.B 101:10542-10547.
Zscherp C, Schlesinger R, Tittor J, Oesterhelt D, Heberle J (1999) In situ determination of transient
pKa changes of internal amino acids of bacteriorhodopsin by using time-resolved attenuated total
reflection Fourier-transform infrared spectroscopy. Proc Natl Acad Sci USA 96:5498-5503.
G. BiiLDT et al.: Structure, Dynamics and Function of the Proton Pump Bacteriorhodopsin
Rammelsberg R, HeEling B, Chorongiewski H, Gerwert K (1997) Molecular Reaction Mechanism of
Proteins Monitored by Nanosecond Step-Scan FT-IR Difference Spectroscopy. Appl.Spectrosc.
51:558-562.
R6dig C, Chizhov I, Weidlich 0, Siebert F (1999) Time-Resolved Step-Scan Fourier Transform Infrared Spectroscopy Reveals Differences between Early and Late M Intermediates of Bacteriorhodopsin. Biophys] 76:2687-2701.
Schertler G F X, Bartunik H D, Michel H, Oesterhelt D (1993) Orthorhombic crystal form of bacteriorhodopsin nucleated on benzamidine diffracting to 3.6 A. J. Mol. BioI. 234, 156-164
Siebert F (1990) Resonance Raman and infrared difference spectroscopy of retinal proteins. Methods
EnzymoI189:123-136.
Takeda K, Sato H, Hino T, Kono M, Fukuda K, Sakurai I, Okada T, Kouyama T (1998) A Novel Threedimensional Crystal of Bacteriorhodopsin Obtained by Successive Fusion of the Vesicular Assemblies. J. Mol. BioI. 283,463-474
Thiedemann G, Heberle J, Dencher N A (1992) Structures and Functions of Retinal Proteins. Colloque
ENSERM/John Libbey Eurotext Ltd, Vol. 221, 217
Trewhella J, Popot J L, Zaccai G, Engelman D M (1986) Localization of two chymotryptic fragments
in the structure of renatured Bacteriorhodopsin by neutron diffraction. EMBO J. 5, 3045-3049
Trewhella J, Anderson S, Fox R, Gogol E, Khan S, Engelman D, Zaccai G. (1983) Assignment of Segments of the Bacteriorhodopsin to Positions in the Structural Map. Biophys. J. 42, 233-241
Unwin P N T, Henderson R J (1975) Molecular Structure Determination by Electron Microscopy of
Unstained Crystalline Specimens. J. Mol. BioI. 94, 425-440
Varo G, Lanyi J (1990) Pathways of the rise and decay of the M photointermediate(s) of bacteriorhodopsin. Biochemistry 29,2241-2250
Weidlich 0, Siebert F (1993) Time Resolved Step-Scan FTIR Investigations of the Transition from KL
to L in the Bacteriorhodpsin Photocycle: Identification of Chromophore Twists by Assigning
Hydrogen-Out-Of-Plane (HOOP) Bending Vibrations. Appl.Spectrosc. 47:1394-1400.
Zaccai G, Gilmore D J (1979) Areas ofhydration,)n the purple membrane of Halobacterium halobium:
a neutron diffraction study. J. Mol. BioI. 132, 181-191
Zscherp C, Heberle J (1997) Infrared difference spectra of the intermediates L, M, N, and 0 of the bacteriorhodopsin photoreaction obtained by time-resolved attenuated total reflection spectroscopy.
].Phys.Chem.B 101:10542-10547.
Zscherp C, Schlesinger R, Tittor J, Oesterhelt D, Heberle J (1999) In situ determination of transient
pKa changes of internal amino acids of bacteriorhodopsin by using time-resolved attenuated total
reflection Fourier-transform infrared spectroscopy. Proc Natl Acad Sci USA 96:5498-5503.