Protein Structure and Dynamics by NMR in Solution
115
Haon S, Auge S, Tropis M, Milon A, Lindley ND (1993) Low cost production of perdeuterated biomass
using methylotrophic yeast. J Lab Comp Radiopharm 33: 1053-1063.
Hernandez JF, Bersch B, Petillot Y, Gagnon J, Arlaud GJ (1997) Chemical synthesis and characterization ofthe epidermal growth factor-like module of human complement protease C1r. J Pept Res 49:
221-231.
Hore PJ (1989) Solvent suppression. Meth Enzymol176: 64-77.
Katz JJ, Crespi HL (1966) Deuterated organisms: cultivation and uses. Science 151: 1187-1194.
Kohno T, Kusunoki H, Sato K, Wakamatsu K. (1998) A new general approach for the biosynthesis of stable isotope-enriched peptides using a decahistidine-tagged ubiquitin fusion system: an application to
the production of mastoparan-X uniformly enriched with l5N and l5N/l3e. J Biomol NMR 12: 109-121.
Lee AL, Volkman BF, Robertson SA, Rudner DZ, Barbash DA, Cline TW, Kanaar R, Rio DC, Wemmer
DE (1997) Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sexlethal. Biochemistry 36: 14306-14317.
LeMaster DM (1990) Deuterium labelling in NMR structural analysis of larger proteins. Q Rev Biophys 23: l33 -74.
Lipari G, Szabo A (1982). Model-free approach to the interpretation of nuclear magnetic-resonance
relaxation in macromolecules 1. theory and range of validity. J Am Chern Soc 104: 4546-4559.
Marion D, Kay LE, Sparks SW, Torchia DA, Bax A (1989) 3-Dimensional Heteronuclear NMR of I5N
Labeled Proteins. J Am Chern Soc 111: 1515-1517.
McIntosh LP, Dahlquist FW. (1990) Biosynthetic incorporation of lsN and 13C for assignment and
interpretation of nuclear magnetic resonance spectra. Q Rev Biophys 23: 1-38.
McKay RT, Pearlstone JR, Corson DC, Gagne SM, Smillie LB, Sykes BD (1998) Structure and interaction site of the regulatory domain of troponin-c when complexed with the 96-148 region of
troponin-I. Biochemistry 37: 12419-12430.
Meissner A, Duus JO, S0rensen OW (1997) Spin-state-selective excitation. Application for E. COSYtype measurement of JHH coupling constants. J. Magn. Res. 128: 92-97.
Mierke DF, Kessler H (1992) Combined use of homo- and heteronuclear coupling constants as
restraints in molecular dynamics simulations. Biopolymers 32: 1277-1282.
Neuhaus D, Willamson M. (1989) The nuclear Overhauser effect in structural and conformational
analysis, VCH publishers, New-York.
Northrup SH, Bowles JO, Reynolds JC (1988) Brownian dynamics of cytochrome c and cytochrome c
peroxidase association. Science 241: 67 -70.
Oldfield E (1995) Chemical shifts and three-dimensional protein structure. J Biomol NMR 5: 217 -225.
Ottiger M, Tjandra N, Bax A (1997) Magnetic field dependent amide lsN chemical shifts in a proteinDNA complex resulting from magnetic ordering in solution. J Am Chern Soc 119: 9825-9830.
Peng JW, Wagner G (1992) Mapping of the spectral densities of N-H bond motions in eglin c using
heteronuclear relaxation experiments. Biochemistry 31: 8571-86.
Persson KEM, Astermark J, Bjork I, Stenflo J (1998) Calcium binding to the first EGF-like module of
human factor IX in a recombinant fragment containing residue 1-85. FEBS Lett. 421: 100-104.
Pervushin K, Riek R, Wider G, Wuthrich K (1997) Attenuated T2 relaxation by mutual cancellation of
dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of
very large biological macromolecules in solution. Proc Nat! Acad Sci USA 94: 12366-71.
Pettigrew GW, Moore GR (1987). Cytochromes c: biological aspects. Springer-Verlag, Berlin, Heidelberg, New-York.
Piotto M, Saudek V, Sklenar V (1992) Gradient-tailored excitation for single-quantum NMR spectroscopy in aqueous solutions. J Biomol NMR 2: 661-665.
Prosser RS, Losonczi JA, Shiyanovskaya IV (1998) Use of a novel aqueous liquid crystalline medium
for high-resolution NMR of macromolecules in solution. J Am Chern Soc 120: 11010-11011.
Qin J, Clore GM, Kennedy WM, Huth JR, Gronenborn AM (1995) Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF-KB. Structure 1995 3: 289-297.
Rajagopal P, Waygood EB, Reizer J, Saier MH Jr, KIevit RE (1997) Demonstration of protein-protein
interaction specificity by NMR chemical shift mapping. Protein Sci 6: 2624-2627.
Rao Z, Handford PA, Mayhew M, Knott V, Brownlee GG, Stuart D (1995) The structure of a Ca 2 +_
binding epidermal growth factor-like domain: its role in protein-protein interactions. Cell 82:
l31-141.
Reif B, Hennig M, Griesinger C (1997) Direct measurement of angles between bond vectors in highresolution NMR. Science 276: 1230-1233.
Rosen MK, Gardner KH, Willis RC, Parris WE, Pawson T, Kay LE. (1996) Selective methyl group protonation of perdeuterated proteins. J Mol BioI 263: 627-36.
Sanders CR., Prosser, RS. (1998) Bicelles: a model membrane system for all seasons? Structure 6:
1227 -1234.
115
Haon S, Auge S, Tropis M, Milon A, Lindley ND (1993) Low cost production of perdeuterated biomass
using methylotrophic yeast. J Lab Comp Radiopharm 33: 1053-1063.
Hernandez JF, Bersch B, Petillot Y, Gagnon J, Arlaud GJ (1997) Chemical synthesis and characterization ofthe epidermal growth factor-like module of human complement protease C1r. J Pept Res 49:
221-231.
Hore PJ (1989) Solvent suppression. Meth Enzymol176: 64-77.
Katz JJ, Crespi HL (1966) Deuterated organisms: cultivation and uses. Science 151: 1187-1194.
Kohno T, Kusunoki H, Sato K, Wakamatsu K. (1998) A new general approach for the biosynthesis of stable isotope-enriched peptides using a decahistidine-tagged ubiquitin fusion system: an application to
the production of mastoparan-X uniformly enriched with l5N and l5N/l3e. J Biomol NMR 12: 109-121.
Lee AL, Volkman BF, Robertson SA, Rudner DZ, Barbash DA, Cline TW, Kanaar R, Rio DC, Wemmer
DE (1997) Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sexlethal. Biochemistry 36: 14306-14317.
LeMaster DM (1990) Deuterium labelling in NMR structural analysis of larger proteins. Q Rev Biophys 23: l33 -74.
Lipari G, Szabo A (1982). Model-free approach to the interpretation of nuclear magnetic-resonance
relaxation in macromolecules 1. theory and range of validity. J Am Chern Soc 104: 4546-4559.
Marion D, Kay LE, Sparks SW, Torchia DA, Bax A (1989) 3-Dimensional Heteronuclear NMR of I5N
Labeled Proteins. J Am Chern Soc 111: 1515-1517.
McIntosh LP, Dahlquist FW. (1990) Biosynthetic incorporation of lsN and 13C for assignment and
interpretation of nuclear magnetic resonance spectra. Q Rev Biophys 23: 1-38.
McKay RT, Pearlstone JR, Corson DC, Gagne SM, Smillie LB, Sykes BD (1998) Structure and interaction site of the regulatory domain of troponin-c when complexed with the 96-148 region of
troponin-I. Biochemistry 37: 12419-12430.
Meissner A, Duus JO, S0rensen OW (1997) Spin-state-selective excitation. Application for E. COSYtype measurement of JHH coupling constants. J. Magn. Res. 128: 92-97.
Mierke DF, Kessler H (1992) Combined use of homo- and heteronuclear coupling constants as
restraints in molecular dynamics simulations. Biopolymers 32: 1277-1282.
Neuhaus D, Willamson M. (1989) The nuclear Overhauser effect in structural and conformational
analysis, VCH publishers, New-York.
Northrup SH, Bowles JO, Reynolds JC (1988) Brownian dynamics of cytochrome c and cytochrome c
peroxidase association. Science 241: 67 -70.
Oldfield E (1995) Chemical shifts and three-dimensional protein structure. J Biomol NMR 5: 217 -225.
Ottiger M, Tjandra N, Bax A (1997) Magnetic field dependent amide lsN chemical shifts in a proteinDNA complex resulting from magnetic ordering in solution. J Am Chern Soc 119: 9825-9830.
Peng JW, Wagner G (1992) Mapping of the spectral densities of N-H bond motions in eglin c using
heteronuclear relaxation experiments. Biochemistry 31: 8571-86.
Persson KEM, Astermark J, Bjork I, Stenflo J (1998) Calcium binding to the first EGF-like module of
human factor IX in a recombinant fragment containing residue 1-85. FEBS Lett. 421: 100-104.
Pervushin K, Riek R, Wider G, Wuthrich K (1997) Attenuated T2 relaxation by mutual cancellation of
dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of
very large biological macromolecules in solution. Proc Nat! Acad Sci USA 94: 12366-71.
Pettigrew GW, Moore GR (1987). Cytochromes c: biological aspects. Springer-Verlag, Berlin, Heidelberg, New-York.
Piotto M, Saudek V, Sklenar V (1992) Gradient-tailored excitation for single-quantum NMR spectroscopy in aqueous solutions. J Biomol NMR 2: 661-665.
Prosser RS, Losonczi JA, Shiyanovskaya IV (1998) Use of a novel aqueous liquid crystalline medium
for high-resolution NMR of macromolecules in solution. J Am Chern Soc 120: 11010-11011.
Qin J, Clore GM, Kennedy WM, Huth JR, Gronenborn AM (1995) Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF-KB. Structure 1995 3: 289-297.
Rajagopal P, Waygood EB, Reizer J, Saier MH Jr, KIevit RE (1997) Demonstration of protein-protein
interaction specificity by NMR chemical shift mapping. Protein Sci 6: 2624-2627.
Rao Z, Handford PA, Mayhew M, Knott V, Brownlee GG, Stuart D (1995) The structure of a Ca 2 +_
binding epidermal growth factor-like domain: its role in protein-protein interactions. Cell 82:
l31-141.
Reif B, Hennig M, Griesinger C (1997) Direct measurement of angles between bond vectors in highresolution NMR. Science 276: 1230-1233.
Rosen MK, Gardner KH, Willis RC, Parris WE, Pawson T, Kay LE. (1996) Selective methyl group protonation of perdeuterated proteins. J Mol BioI 263: 627-36.
Sanders CR., Prosser, RS. (1998) Bicelles: a model membrane system for all seasons? Structure 6:
1227 -1234.