224
FRIEDHELM HILDEBRANDT AND IVA SINGH-SAWHNEY
27. Loh EY, Elliott JF, Cwirla S, Lanier LL, Davis MM (1989) Polymerase chain reaction
with single-sided specifieity:analysis ofT cell receptor d chain. Science 243:217-220
28. Frohman MA, Dush MK, Martin GR (1988) Rapid production offull-length cDNAs
from rare transcripts: amplifacation using a single gene-specific loigonucleotide
primer. Proc Natl Acad Sei U.S.A. 85:8998-9002
29. Lee C.C. et al. (1988) Generation of cDNA probes directed by amino acid sequence:
cloning of urate oxidase. Science 239:1288-1291
30. Varadi A, Gilmore-Hebert M, Benz EJ (1989) Amplification ofthe phosphorylation
site- ATP-binding site cDNA fragment of the Na+, K+ -ATPase and the Ca 2 + -ATPase
of Drosophila melanogaster by polymerase chain reaction. FEBS let 258:203-207
31. Rappolee DA, Mark D, Banda M, W erb Z (1988) Wound macrophages express TGFa and other growth factors in vivo: analysis by mRNA phenotyping. Seience 241:708712
32. Tecott LH, Barchas JD, Eberwine JH (1988) In situ transcription: specific synthesis of
complementary DNA in fixed tissue sections. Seience 240:1661-1664
33. Vigilant L, Pennington R, Harpending H, Kocher T, Wilson AC (1989) Mitochondrial DNA sequences in single hairs from a southern African population. Proc Natl
Acad Sei U.S.A. 86:9350-9354
34. Williams SD, Kwok S {1991) In: Lenette EH (ed) Laboratory diagnosis ofviral infections. Dekker, New York, pp 147-173
35. Goodenow Met al. (1989) HIV -1 isolates are rapidly evolving quasispecies: evidence
for viral mixtures and preferred nucleotide substitutions. J Acquired Immune Def
Syndr 2:344-352
36. Lathe R (1985) Synthetic oligonucleotide probes deduced from amino acid sequence
data. J Mol Biol183:1-12
37. Scharf SJ, Horn GT, Erlich HA {1986) Direct cloning and sequence analysis of enzymatically amplified genomic sequences. Science 233:10761078
38. Higuchi R (1989) In: Erlich H (ed) PCR technology: principles and applications for
DNA Amplification. Stockton, New York, pp 61-70
39. Sakar G, Sommer SS (1989) Access to a messenger RNA sequence or its protein
product is not limited by tissue or species specificity. Science 244:331-334
40. Martin et al. (1990) The GAP-related domain of the neurofibromatiosis type 1 gene
product interacts with ras p21. Cell 63:843-849
41. Erlich H {1991) Recent advances in the polymerase chain reaction. Science 252:16431651
42. Gyllenstein UB, Erlich HA {1988) Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA
locus. Proc Natl Acad Sei U.S.A. 85:7652-7656
43. Saiki RK, Bugawan TL, Horn GT, Mullis KB, Erlich HA (1986) Analysis of enzymatically amplified ß-globin and HLA-DQa DNA with allele-speeific oligonucleotide
probes. Nature 324:163-166
44. Wong C, et al. (1986) Characterization of ß-thalassaemia mutations using direct
genomic sequencing of amplified single copy DNA. Nature 330:384-386
45. Saiki RK et al. (1988) Diagnosis of sickle call anemia and ß-thalassemia with enzymatically amplified DNA and nonradioactive allele.speeific oligonucleotide probes.
N Engl J Med 319:537-541
46. Conner BJ et al. (1983) Detection of sickle cell b 5 -globin allele by hybridization with
synthetic oligonucleotides. Proc Natl Acad Sei U.S.A. 80:278-282
FRIEDHELM HILDEBRANDT AND IVA SINGH-SAWHNEY
27. Loh EY, Elliott JF, Cwirla S, Lanier LL, Davis MM (1989) Polymerase chain reaction
with single-sided specifieity:analysis ofT cell receptor d chain. Science 243:217-220
28. Frohman MA, Dush MK, Martin GR (1988) Rapid production offull-length cDNAs
from rare transcripts: amplifacation using a single gene-specific loigonucleotide
primer. Proc Natl Acad Sei U.S.A. 85:8998-9002
29. Lee C.C. et al. (1988) Generation of cDNA probes directed by amino acid sequence:
cloning of urate oxidase. Science 239:1288-1291
30. Varadi A, Gilmore-Hebert M, Benz EJ (1989) Amplification ofthe phosphorylation
site- ATP-binding site cDNA fragment of the Na+, K+ -ATPase and the Ca 2 + -ATPase
of Drosophila melanogaster by polymerase chain reaction. FEBS let 258:203-207
31. Rappolee DA, Mark D, Banda M, W erb Z (1988) Wound macrophages express TGFa and other growth factors in vivo: analysis by mRNA phenotyping. Seience 241:708712
32. Tecott LH, Barchas JD, Eberwine JH (1988) In situ transcription: specific synthesis of
complementary DNA in fixed tissue sections. Seience 240:1661-1664
33. Vigilant L, Pennington R, Harpending H, Kocher T, Wilson AC (1989) Mitochondrial DNA sequences in single hairs from a southern African population. Proc Natl
Acad Sei U.S.A. 86:9350-9354
34. Williams SD, Kwok S {1991) In: Lenette EH (ed) Laboratory diagnosis ofviral infections. Dekker, New York, pp 147-173
35. Goodenow Met al. (1989) HIV -1 isolates are rapidly evolving quasispecies: evidence
for viral mixtures and preferred nucleotide substitutions. J Acquired Immune Def
Syndr 2:344-352
36. Lathe R (1985) Synthetic oligonucleotide probes deduced from amino acid sequence
data. J Mol Biol183:1-12
37. Scharf SJ, Horn GT, Erlich HA {1986) Direct cloning and sequence analysis of enzymatically amplified genomic sequences. Science 233:10761078
38. Higuchi R (1989) In: Erlich H (ed) PCR technology: principles and applications for
DNA Amplification. Stockton, New York, pp 61-70
39. Sakar G, Sommer SS (1989) Access to a messenger RNA sequence or its protein
product is not limited by tissue or species specificity. Science 244:331-334
40. Martin et al. (1990) The GAP-related domain of the neurofibromatiosis type 1 gene
product interacts with ras p21. Cell 63:843-849
41. Erlich H {1991) Recent advances in the polymerase chain reaction. Science 252:16431651
42. Gyllenstein UB, Erlich HA {1988) Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA
locus. Proc Natl Acad Sei U.S.A. 85:7652-7656
43. Saiki RK, Bugawan TL, Horn GT, Mullis KB, Erlich HA (1986) Analysis of enzymatically amplified ß-globin and HLA-DQa DNA with allele-speeific oligonucleotide
probes. Nature 324:163-166
44. Wong C, et al. (1986) Characterization of ß-thalassaemia mutations using direct
genomic sequencing of amplified single copy DNA. Nature 330:384-386
45. Saiki RK et al. (1988) Diagnosis of sickle call anemia and ß-thalassemia with enzymatically amplified DNA and nonradioactive allele.speeific oligonucleotide probes.
N Engl J Med 319:537-541
46. Conner BJ et al. (1983) Detection of sickle cell b 5 -globin allele by hybridization with
synthetic oligonucleotides. Proc Natl Acad Sei U.S.A. 80:278-282